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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: GFRA1_HUMAN (P56159)

Summary

This is the summary of UniProt entry GFRA1_HUMAN (P56159).

Description: GDNF family receptor alpha-1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 465 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 18
low_complexity n/a 2 18
Pfam GDNF 29 110
Pfam GDNF 154 233
Pfam GDNF 243 337
low_complexity n/a 361 369
disorder n/a 371 380
disorder n/a 382 386
disorder n/a 428 431
transmembrane n/a 443 461
low_complexity n/a 443 461

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P56159. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MFLATLYFAL PLLDLLLSAE VSGGDRLDCV KASDQCLKEQ SCSTKYRTLR
50
51
QCVAGKETNF SLASGLEAKD ECRSAMEALK QKSLYNCRCK RGMKKEKNCL
100
101
RIYWSMYQSL QGNDLLEDSP YEPVNSRLSD IFRVVPFISD VFQQVEHIPK
150
151
GNNCLDAAKA CNLDDICKKY RSAYITPCTT SVSNDVCNRR KCHKALRQFF
200
201
DKVPAKHSYG MLFCSCRDIA CTERRRQTIV PVCSYEEREK PNCLNLQDSC
250
251
KTNYICRSRL ADFFTNCQPE SRSVSSCLKE NYADCLLAYS GLIGTVMTPN
300
301
YIDSSSLSVA PWCDCSNSGN DLEECLKFLN FFKDNTCLKN AIQAFGNGSD
350
351
VTVWQPAFPV QTTTATTTTA LRVKNKPLGP AGSENEIPTH VLPPCANLQA
400
401
QKLKSNVSGN THLCISNGNY EKEGLGASSH ITTKSMAAPP SCGLSPLLVL
450
451
VVTALSTLLS LTETS                                      
465
 

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Checksums:
CRC64:91A550D06A6777BD
MD5:0a2fda3680b9bece9691a49d09c7b8d8

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.