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4  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: NU107_HUMAN (P57740)

Summary

This is the summary of UniProt entry NU107_HUMAN (P57740).

Description: Nuclear pore complex protein Nup107
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 925 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 2
disorder n/a 4 22
disorder n/a 24 66
disorder n/a 82 83
disorder n/a 134 137
Pfam Nup84_Nup100 209 908
disorder n/a 331 332
low_complexity n/a 334 346
disorder n/a 394 395
disorder n/a 654 658
disorder n/a 730 738
disorder n/a 781 783
low_complexity n/a 892 908

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P57740. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDRSGFGEIS SPVIREAEVT RTARKQSAQK RVLLQASQDE NFGNTTPRNQ
50
51
VIPRTPSSFR QPFTPTSRSL LRQPDISCIL GTGGKSPRLT QSSGFFGNLS
100
101
MVTNLDDSNW AAAFSSQRSG LFTNTEPHSI TEDVTISAVM LREDDPGEAA
150
151
SMSMFSDFLQ SFLKHSSSTV FDLVEEYENI CGSQVNILSK IVSRATPGLQ
200
201
KFSKTASMLW LLQQEMVTWR LLASLYRDRI QSALEEESVF AVTAVNASEK
250
251
TVVEALFQRD SLVRQSQLVV DWLESIAKDE IGEFSDNIEF YAKSVYWENT
300
301
LHTLKQRQLT SYVGSVRPLV TELDPDAPIR QKMPLDDLDR EDEVRLLKYL
350
351
FTLIRAGMTE EAQRLCKRCG QAWRAATLEG WKLYHDPNVN GGTELEPVEG
400
401
NPYRRIWKIS CWRMAEDELF NRYERAIYAA LSGNLKQLLP VCDTWEDTVW
450
451
AYFRVMVDSL VEQEIQTSVA TLDETEELPR EYLGANWTLE KVFEELQATD
500
501
KKRVLEENQE HYHIVQKFLI LGDIDGLMDE FSKWLSKSRN NLPGHLLRFM
550
551
THLILFFRTL GLQTKEEVSI EVLKTYIQLL IREKHTNLIA FYTCHLPQDL
600
601
AVAQYALFLE SVTEFEQRHH CLELAKEADL DVATITKTVV ENIRKKDNGE
650
651
FSHHDLAPAL DTGTTEEDRL KIDVIDWLVF DPAQRAEALK QGNAIMRKFL
700
701
ASKKHEAAKE VFVKIPQDSI AEIYNQCEEQ GMESPLPAED DNAIREHLCI
750
751
RAYLEAHETF NEWFKHMNSV PQKPALIPQP TFTEKVAHEH KEKKYEMDFG
800
801
IWKGHLDALT ADVKEKMYNV LLFVDGGWMV DVREDAKEDH ERTHQMVLLR
850
851
KLCLPMLCFL LHTILHSTGQ YQECLQLADM VSSERHKLYL VFSKEELRKL
900
901
LQKLRESSLM LLDQGLDPLG YEIQL                           
925
 

Show the unformatted sequence.

Checksums:
CRC64:CE1E4DA6C832A5A5
MD5:3746f69ca2e8f5de558acad6b35f4f0f

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Nup84_Nup100 209 - 908 5A9Q 4 209 - 908 Jmol OpenAstexViewer
D 209 - 908 Jmol OpenAstexViewer
M 209 - 908 Jmol OpenAstexViewer
V 209 - 908 Jmol OpenAstexViewer
666 - 908 3CQG A 666 - 908 Jmol OpenAstexViewer
667 - 908 3CQC A 667 - 908 Jmol OpenAstexViewer
3I4R A 667 - 908 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.