Summary
This is the summary of UniProt entry RGS8_HUMAN (P57771).
Description: | Regulator of G-protein signaling 8 |
Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
|
Length: | 180 amino acids |
Reference Proteome: |
![]() |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
Download the data used to generate the domain graphic in JSON format.
Show or hide the data used to generate the graphic in JSON format.
Source | Domain | Start | End |
---|---|---|---|
Pfam | RGS | 56 | 171 |
disorder | n/a | 127 | 128 |
low_complexity | n/a | 170 | 179 |
Show or hide domain scores.
Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P57771. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
Sequence: | 1
MAALLMPRRN KGMRTRLGCL SHKSDSCSDF TAILPDKPNR ALKRLSTEEA
50 51
TRWADSFDVL LSHKYGVAAF RAFLKTEFSE ENLEFWLACE EFKKTRSTAK
100 101
LVSKAHRIFE EFVDVQAPRE VNIDFQTREA TRKNLQEPSL TCFDQAQGKV
150 151
HSLMEKDSYP RFLRSKMYLD LLSQSQRRLS
180
Show the unformatted sequence. |
Checksums: |
CRC64:198965B4C27F64C9
MD5:99f470573d930af52f035c7b1f23d029
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
---|---|---|---|---|---|
RGS | 56 - 171 | 2IHD | A | 56 - 171 | Jmol OpenAstexViewer |
2ODE | B | 56 - 171 | Jmol OpenAstexViewer | ||
D | 56 - 171 | Jmol OpenAstexViewer | |||
5DO9 | B | 56 - 171 | Jmol OpenAstexViewer | ||
D | 56 - 171 | Jmol OpenAstexViewer | |||
F | 56 - 171 | Jmol OpenAstexViewer |
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.