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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SESN3_HUMAN (P58005)

Summary

This is the summary of UniProt entry SESN3_HUMAN (P58005).

Description: Sestrin-3 {ECO:0000305}
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 492 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 3
Pfam PA26 39 491
low_complexity n/a 189 203
coiled_coil n/a 255 289
disorder n/a 269 288
low_complexity n/a 273 284

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P58005. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MNRGGGSPSA AANYLLCTNC RKVLRKDKRI RVSQPLTRGP SAFIPEKEVV
50
51
QANTVDERTN FLVEEYSTSG RLDNITQVMS LHTQYLESFL RSQFYMLRMD
100
101
GPLPLPYRHY IAIMAAARHQ CSYLINMHVD EFLKTGGIAE WLNGLEYVPQ
150
151
RLKNLNEINK LLAHRPWLIT KEHIQKLVKT GENNWSLPEL VHAVVLLAHY
200
201
HALASFVFGS GINPERDPEI SNGFRLISVN NFCVCDLAND NNIENASLSG
250
251
SNFGIVDSLS ELEALMERMK RLQEEREDEE ASQEEMSTRF EKEKKESLFV
300
301
VSGDTFHSFP HSDFEDDMII TSDVSRYIED PGFGYEDFAR RGEEHLPTFR
350
351
AQDYTWENHG FSLVNRLYSD IGHLLDEKFR MVYNLTYNTM ATHEDVDTTM
400
401
LRRALFNYVH CMFGIRYDDY DYGEVNQLLE RSLKVYIKTV TCYPERTTKR
450
451
MYDSYWRQFK HSEKVHVNLL LMEARMQAEL LYALRAITRH LT        
492
 

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Checksums:
CRC64:0B165C6BAE5A49CF
MD5:b7e14ceed1275fecce433b5687ba4045

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.