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4  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SNP25_HUMAN (P60880)

Summary

This is the summary of UniProt entry SNP25_HUMAN (P60880).

Description: Synaptosomal-associated protein 25
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 206 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 24
coiled_coil n/a 4 31
disorder n/a 27 34
disorder n/a 47 48
coiled_coil n/a 50 77
disorder n/a 55 73
Pfam SNAP-25 91 141
disorder n/a 106 108
disorder n/a 112 121
disorder n/a 132 138
disorder n/a 140 153
disorder n/a 168 169
disorder n/a 171 206
coiled_coil n/a 178 198

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P60880. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAEDADMRNE LEEMQRRADQ LADESLESTR RMLQLVEESK DAGIRTLVML
50
51
DEQGEQLERI EEGMDQINKD MKEAEKNLTD LGKFCGLCVC PCNKLKSSDA
100
101
YKKAWGNNQD GVVASQPARV VDEREQMAIS GGFIRRVTND ARENEMDENL
150
151
EQVSGIIGNL RHMALDMGNE IDTQNRQIDR IMEKADSNKT RIDEANQRAT
200
201
KMLGSG                                                
206
 

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Checksums:
CRC64:FBED2B082A4CB6A6
MD5:bf9c69f64b0a1f741fcc0cbd0c262d49

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
SNAP-25 111 - 120 5W7I B 1 - 10 Jmol OpenAstexViewer
D 1 - 10 Jmol OpenAstexViewer
5W7J B 1 - 10 Jmol OpenAstexViewer
D 1 - 10 Jmol OpenAstexViewer
131 - 141 2N1T D 131 - 141 Jmol OpenAstexViewer
139 - 141 1KIL D 139 - 141 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.