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9  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RAB8A_HUMAN (P61006)

Summary

This is the summary of UniProt entry RAB8A_HUMAN (P61006).

Description: Ras-related protein Rab-8A
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 207 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam Ras 10 171
disorder n/a 174 192

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P61006. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAKTYDYLFK LLLIGDSGVG KTCVLFRFSE DAFNSTFIST IGIDFKIRTI
50
51
ELDGKRIKLQ IWDTAGQERF RTITTAYYRG AMGIMLVYDI TNEKSFDNIR
100
101
NWIRNIEEHA SADVEKMILG NKCDVNDKRQ VSKERGEKLA LDYGIKFMET
150
151
SAKANINVEN AFFTLARDIK AKMDKKLEGN SPQGSNQGVK ITPDQQKRSS
200
201
FFRCVLL                                               
207
 

Show the unformatted sequence.

Checksums:
CRC64:AA52DBF54A2CD056
MD5:f128dbfbade37b68cd77254a8fe70e1f

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Ras 10 - 171 3QBT A 10 - 171 Jmol OpenAstexViewer
C 10 - 171 Jmol OpenAstexViewer
E 10 - 171 Jmol OpenAstexViewer
G 10 - 171 Jmol OpenAstexViewer
3TNF A 10 - 171 Jmol OpenAstexViewer
4LHV A 10 - 171 Jmol OpenAstexViewer
B 10 - 171 Jmol OpenAstexViewer
C 10 - 171 Jmol OpenAstexViewer
D 10 - 171 Jmol OpenAstexViewer
E 10 - 171 Jmol OpenAstexViewer
4LHW A 10 - 171 Jmol OpenAstexViewer
B 10 - 171 Jmol OpenAstexViewer
C 10 - 171 Jmol OpenAstexViewer
D 10 - 171 Jmol OpenAstexViewer
E 10 - 171 Jmol OpenAstexViewer
4LHX A 10 - 171 Jmol OpenAstexViewer
B 10 - 171 Jmol OpenAstexViewer
4LHY A 10 - 171 Jmol OpenAstexViewer
B 10 - 171 Jmol OpenAstexViewer
4LHZ A 10 - 171 Jmol OpenAstexViewer
B 10 - 171 Jmol OpenAstexViewer
4LI0 A 10 - 171 Jmol OpenAstexViewer
B 10 - 171 Jmol OpenAstexViewer
5SZI A 10 - 171 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.