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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RAB14_HUMAN (P61106)

Summary

This is the summary of UniProt entry RAB14_HUMAN (P61106).

Description: Ras-related protein Rab-14
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 215 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam Ras 13 174
coiled_coil n/a 125 145
disorder n/a 183 215

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P61106. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MATAPYNYSY IFKYIIIGDM GVGKSCLLHQ FTEKKFMADC PHTIGVEFGT
50
51
RIIEVSGQKI KLQIWDTAGQ ERFRAVTRSY YRGAAGALMV YDITRRSTYN
100
101
HLSSWLTDAR NLTNPNTVII LIGNKADLEA QRDVTYEEAK QFAEENGLLF
150
151
LEASAKTGEN VEDAFLEAAK KIYQNIQDGS LDLNAAESGV QHKPSAPQGG
200
201
RLTSEPQPQR EGCGC                                      
215
 

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Checksums:
CRC64:BC8A8B98FB9944AC
MD5:dc482aca2ecc21b2f4115b9c9173994a

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Ras 13 - 173 1Z0F A 13 - 173 Jmol OpenAstexViewer
13 - 174 4D0G A 13 - 174 Jmol OpenAstexViewer
4DRZ A 13 - 174 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.