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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: LEU3_THETH (P61495)

Summary

This is the summary of UniProt entry LEU3_THETH (P61495).

Description: 3-isopropylmalate dehydrogenase EC=1.1.1.85
Source organism: Thermus thermophilus (NCBI taxonomy ID )
Length: 345 amino acids
Reference Proteome: x

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam Iso_dh 2 343

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P61495. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKVAVLPGDG IGPEVTEAAL KVLRALDEAE GLGLAYEVFP FGGAAIDAFG
50
51
EPFPEPTRKG VEEAEAVLLG SVGGPKWDGL PRKISPETGL LSLRKSQDLF
100
101
ANLRPAKVFP GLERLSPLKE EIARGVDVLI VRELTGGIYF GEPRGMSEAE
150
151
AWNTERYSKP EVERVARVAF EAARKRRKHV VSVDKANVLE VGEFWRKTVE
200
201
EVGRGYPDVA LEHQYVDAAA MHLVRSPARF DVVVTGNIFG DILSDLASVL
250
251
PGSLGLLPSA SLGRGTPVFE PVHGSAPDIA GKGIANPTAA ILSAAMMLEH
300
301
AFGLVELARK VEDAVAKALL ETPPPDLGGS AGTEAFTATV LRHLA     
345
 

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Checksums:
CRC64:3521F7363A0550C5
MD5:f4d8b2e5c7a3e88dbecf1035a74fe5b4

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Iso_dh 2 - 343 1WAL A 2 - 343 Jmol OpenAstexViewer