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105  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: H4_HUMAN (P62805)

Summary

This is the summary of UniProt entry H4_HUMAN (P62805).

Description: Histone H4
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 103 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 18
low_complexity n/a 2 20
Pfam CENP-T_C 18 99
disorder n/a 22 23

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P62805. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSGRGKGGKG LGKGGAKRHR KVLRDNIQGI TKPAIRRLAR RGGVKRISGL
50
51
IYEETRGVLK VFLENVIRDA VTYTEHAKRK TVTAMDVVYA LKRQGRTLYG
100
101
FGG                                                   
103
 

Show the unformatted sequence.

Checksums:
CRC64:A9E5DFD3F8B97598
MD5:cd835bc39369079207f534a9e7ba6095

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
CENP-T_C 18 - 20 3QZT B 17 - 19 Jmol OpenAstexViewer
18 - 21 2KWO B 17 - 20 Jmol OpenAstexViewer
18 - 22 2QQS C 17 - 21 Jmol OpenAstexViewer
3QZS C 17 - 21 Jmol OpenAstexViewer
D 17 - 21 Jmol OpenAstexViewer
4N3W C 17 - 21 Jmol OpenAstexViewer
18 - 23 3F9Y E 17 - 22 Jmol OpenAstexViewer
3F9Z G 17 - 22 Jmol OpenAstexViewer
18 - 24 1ZKK E 17 - 23 Jmol OpenAstexViewer
2KWN B 17 - 23 Jmol OpenAstexViewer
2QQS D 17 - 23 Jmol OpenAstexViewer
3F9W F 17 - 23 Jmol OpenAstexViewer
H 17 - 23 Jmol OpenAstexViewer
3F9X F 17 - 23 Jmol OpenAstexViewer
H 17 - 23 Jmol OpenAstexViewer
3F9Y F 17 - 23 Jmol OpenAstexViewer
3F9Z F 17 - 23 Jmol OpenAstexViewer
H 17 - 23 Jmol OpenAstexViewer
3IJ1 B 17 - 23 Jmol OpenAstexViewer
5TEG D 17 - 23 Jmol OpenAstexViewer
E 17 - 23 Jmol OpenAstexViewer
18 - 25 1ZKK F 17 - 24 Jmol OpenAstexViewer
G 17 - 24 Jmol OpenAstexViewer
3F9W E 17 - 24 Jmol OpenAstexViewer
G 17 - 24 Jmol OpenAstexViewer
3F9X E 17 - 24 Jmol OpenAstexViewer
G 17 - 24 Jmol OpenAstexViewer
3F9Z E 17 - 24 Jmol OpenAstexViewer
3UVY B 17 - 24 Jmol OpenAstexViewer
18 - 28 2LVM B 17 - 27 Jmol OpenAstexViewer
2RNY B 17 - 27 Jmol OpenAstexViewer
18 - 99 3AZL F 17 - 98 Jmol OpenAstexViewer
3X1T F 17 - 98 Jmol OpenAstexViewer
3X1U F 17 - 98 Jmol OpenAstexViewer
3X1V F 17 - 98 Jmol OpenAstexViewer
4YM5 F 17 - 98 Jmol OpenAstexViewer
5AV5 F 17 - 98 Jmol OpenAstexViewer
5AV6 F 17 - 98 Jmol OpenAstexViewer
5AV8 F 17 - 98 Jmol OpenAstexViewer
5AV9 F 17 - 98 Jmol OpenAstexViewer
5AVB F 17 - 98 Jmol OpenAstexViewer
5AVC F 17 - 98 Jmol OpenAstexViewer
5BNX B 17 - 98 Jmol OpenAstexViewer
5BO0 B 17 - 98 Jmol OpenAstexViewer
5GSU F 17 - 98 Jmol OpenAstexViewer
5GT0 F 17 - 98 Jmol OpenAstexViewer
5GTC F 17 - 98 Jmol OpenAstexViewer
5JA4 B 17 - 98 Jmol OpenAstexViewer
5JRG F 17 - 98 Jmol OpenAstexViewer
5X7X F 17 - 98 Jmol OpenAstexViewer
5XF3 F 17 - 98 Jmol OpenAstexViewer
5XF4 F 17 - 98 Jmol OpenAstexViewer
5XF5 F 17 - 98 Jmol OpenAstexViewer
6ETX N 17 - 98 Jmol OpenAstexViewer
19 - 21 3QBY H 18 - 20 Jmol OpenAstexViewer
19 - 24 3JPX B 18 - 23 Jmol OpenAstexViewer
19 - 26 2RJE Q 18 - 25 Jmol OpenAstexViewer
19 - 99 2CV5 F 18 - 98 Jmol OpenAstexViewer
3AZE F 18 - 98 Jmol OpenAstexViewer
3AZH F 18 - 98 Jmol OpenAstexViewer
3WTP F 18 - 98 Jmol OpenAstexViewer
5B2I F 18 - 98 Jmol OpenAstexViewer
5B2J F 18 - 98 Jmol OpenAstexViewer
5GT3 F 18 - 98 Jmol OpenAstexViewer
20 - 21 2IG0 B 19 - 20 Jmol OpenAstexViewer
20 - 98 5BNV B 19 - 97 Jmol OpenAstexViewer
20 - 99 3A6N F 19 - 98 Jmol OpenAstexViewer
3AFA F 19 - 98 Jmol OpenAstexViewer
3AV1 F 19 - 98 Jmol OpenAstexViewer
3AV2 F 19 - 98 Jmol OpenAstexViewer
3AYW F 19 - 98 Jmol OpenAstexViewer
3AZF F 19 - 98 Jmol OpenAstexViewer
3AZG F 19 - 98 Jmol OpenAstexViewer
3AZI F 19 - 98 Jmol OpenAstexViewer
3AZJ F 19 - 98 Jmol OpenAstexViewer
3AZK F 19 - 98 Jmol OpenAstexViewer
3AZM F 19 - 98 Jmol OpenAstexViewer
3AZN F 19 - 98 Jmol OpenAstexViewer
3W97 F 19 - 98 Jmol OpenAstexViewer
3W98 F 19 - 98 Jmol OpenAstexViewer
3W99 F 19 - 98 Jmol OpenAstexViewer
3WA9 F 19 - 98 Jmol OpenAstexViewer
3WAA F 19 - 98 Jmol OpenAstexViewer
3WKJ F 19 - 98 Jmol OpenAstexViewer
3X1S F 19 - 98 Jmol OpenAstexViewer
4YM6 F 19 - 98 Jmol OpenAstexViewer
5B0Y F 19 - 98 Jmol OpenAstexViewer
5B24 F 19 - 98 Jmol OpenAstexViewer
5B31 F 19 - 98 Jmol OpenAstexViewer
5B32 F 19 - 98 Jmol OpenAstexViewer
5B33 F 19 - 98 Jmol OpenAstexViewer
5CPI F 19 - 98 Jmol OpenAstexViewer
5CPJ F 19 - 98 Jmol OpenAstexViewer
5CPK F 19 - 98 Jmol OpenAstexViewer
5GXQ F 19 - 98 Jmol OpenAstexViewer
21 - 99 3W96 F 20 - 98 Jmol OpenAstexViewer
3X1U B 20 - 98 Jmol OpenAstexViewer
4H9N B 20 - 98 Jmol OpenAstexViewer
4H9O B 20 - 98 Jmol OpenAstexViewer
4H9P B 20 - 98 Jmol OpenAstexViewer
4H9Q B 20 - 98 Jmol OpenAstexViewer
4H9R B 20 - 98 Jmol OpenAstexViewer
4Z5T B 20 - 98 Jmol OpenAstexViewer
5B0Z F 20 - 98 Jmol OpenAstexViewer
22 - 99 5AV5 B 21 - 98 Jmol OpenAstexViewer
5AV6 B 21 - 98 Jmol OpenAstexViewer
5AV8 B 21 - 98 Jmol OpenAstexViewer
5AV9 B 21 - 98 Jmol OpenAstexViewer
5AVB B 21 - 98 Jmol OpenAstexViewer
5AVC B 21 - 98 Jmol OpenAstexViewer
5B2I B 21 - 98 Jmol OpenAstexViewer
5B2J B 21 - 98 Jmol OpenAstexViewer
5GSE B 21 - 98 Jmol OpenAstexViewer
P 21 - 98 Jmol OpenAstexViewer
5XF3 B 21 - 98 Jmol OpenAstexViewer
5XF4 B 21 - 98 Jmol OpenAstexViewer
5XF5 B 21 - 98 Jmol OpenAstexViewer
6ETX J 21 - 98 Jmol OpenAstexViewer
6FML R 21 - 98 Jmol OpenAstexViewer
23 - 99 3A6N B 22 - 98 Jmol OpenAstexViewer
3X1T B 22 - 98 Jmol OpenAstexViewer
5B40 F 22 - 98 Jmol OpenAstexViewer
5GT3 B 22 - 98 Jmol OpenAstexViewer
24 - 94 4Z2M H 23 - 93 Jmol OpenAstexViewer
24 - 97 3R45 B 23 - 96 Jmol OpenAstexViewer
24 - 99 5GSE F 23 - 98 Jmol OpenAstexViewer
6BUZ B 24 - 99 Jmol OpenAstexViewer
F 24 - 99 Jmol OpenAstexViewer
6C0W B 23 - 98 Jmol OpenAstexViewer
25 - 42 3CFV E 24 - 41 Jmol OpenAstexViewer
25 - 93 3NQJ B 24 - 92 Jmol OpenAstexViewer
25 - 94 4Z2M J 24 - 93 Jmol OpenAstexViewer
25 - 99 3AN2 F 24 - 98 Jmol OpenAstexViewer
3AZJ B 24 - 98 Jmol OpenAstexViewer
3X1V B 24 - 98 Jmol OpenAstexViewer
4YM5 B 24 - 98 Jmol OpenAstexViewer
4Z5T F 24 - 98 Jmol OpenAstexViewer
5AY8 F 24 - 98 Jmol OpenAstexViewer
5C3I C 24 - 98 Jmol OpenAstexViewer
G 24 - 98 Jmol OpenAstexViewer
O 24 - 98 Jmol OpenAstexViewer
S 24 - 98 Jmol OpenAstexViewer
W 24 - 98 Jmol OpenAstexViewer
5CPK B 24 - 98 Jmol OpenAstexViewer
5GSU B 24 - 98 Jmol OpenAstexViewer
5GT0 B 24 - 98 Jmol OpenAstexViewer
6C0W F 24 - 98 Jmol OpenAstexViewer
6FML N 24 - 98 Jmol OpenAstexViewer
26 - 92 3NQU B 25 - 91 Jmol OpenAstexViewer
26 - 94 5GSE L 25 - 93 Jmol OpenAstexViewer
26 - 99 2CV5 B 25 - 98 Jmol OpenAstexViewer
3AFA B 25 - 98 Jmol OpenAstexViewer
3AN2 B 25 - 98 Jmol OpenAstexViewer
3AV1 B 25 - 98 Jmol OpenAstexViewer
3AV2 B 25 - 98 Jmol OpenAstexViewer
3AYW B 25 - 98 Jmol OpenAstexViewer
3AZE B 25 - 98 Jmol OpenAstexViewer
3AZF B 25 - 98 Jmol OpenAstexViewer
3AZG B 25 - 98 Jmol OpenAstexViewer
3AZH B 25 - 98 Jmol OpenAstexViewer
3AZI B 25 - 98 Jmol OpenAstexViewer
3AZK B 25 - 98 Jmol OpenAstexViewer
3AZL B 25 - 98 Jmol OpenAstexViewer
3AZM B 25 - 98 Jmol OpenAstexViewer
3AZN B 25 - 98 Jmol OpenAstexViewer
3W97 B 25 - 98 Jmol OpenAstexViewer
3W98 B 25 - 98 Jmol OpenAstexViewer
3W99 B 25 - 98 Jmol OpenAstexViewer
3WA9 B 25 - 98 Jmol OpenAstexViewer
3WAA B 25 - 98 Jmol OpenAstexViewer
3WKJ B 25 - 98 Jmol OpenAstexViewer
3WTP B 25 - 98 Jmol OpenAstexViewer
3X1S B 25 - 98 Jmol OpenAstexViewer
4YM6 B 25 - 98 Jmol OpenAstexViewer
5AY8 B 25 - 98 Jmol OpenAstexViewer
5B0Y B 25 - 98 Jmol OpenAstexViewer
5B0Z B 25 - 98 Jmol OpenAstexViewer
5B24 B 25 - 98 Jmol OpenAstexViewer
5B31 B 25 - 98 Jmol OpenAstexViewer
5B32 B 25 - 98 Jmol OpenAstexViewer
5B33 B 25 - 98 Jmol OpenAstexViewer
5B40 B 25 - 98 Jmol OpenAstexViewer
5CPI B 25 - 98 Jmol OpenAstexViewer
5CPJ B 25 - 98 Jmol OpenAstexViewer
5GTC B 25 - 98 Jmol OpenAstexViewer
5GXQ B 25 - 98 Jmol OpenAstexViewer
5JRG B 25 - 98 Jmol OpenAstexViewer
5X7X B 25 - 98 Jmol OpenAstexViewer
27 - 95 5BNV E 26 - 94 Jmol OpenAstexViewer
27 - 99 3W96 B 26 - 98 Jmol OpenAstexViewer
5C3I K 26 - 98 Jmol OpenAstexViewer
5KDM B 26 - 98 Jmol OpenAstexViewer
28 - 42 3CFS E 27 - 41 Jmol OpenAstexViewer
28 - 99 4H9S C 27 - 98 Jmol OpenAstexViewer
D 27 - 98 Jmol OpenAstexViewer
4HGA C 27 - 98 Jmol OpenAstexViewer
29 - 42 3CFV F 28 - 41 Jmol OpenAstexViewer