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74  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RL40_HUMAN (P62987)

Summary

This is the summary of UniProt entry RL40_HUMAN (P62987).

Description: Ubiquitin-60S ribosomal protein L40
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 128 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam ubiquitin 3 74
disorder n/a 26 32
Pfam Ribosomal_L40e 78 127
disorder n/a 114 115
disorder n/a 119 128

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P62987. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MQIFVKTLTG KTITLEVEPS DTIENVKAKI QDKEGIPPDQ QRLIFAGKQL
50
51
EDGRTLSDYN IQKESTLHLV LRLRGGIIEP SLRQLAQKYN CDKMICRKCY
100
101
ARLHPRAVNC RKKKCGHTNN LRPKKKVK                        
128
 

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Checksums:
CRC64:7BCB602ABEFAD02A
MD5:76cfa4408c56f9d20a48509c5e71a79d

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Ribosomal_L40e 78 - 127 4UG0 Lm 78 - 127 Show 3D Structure View in InterPro
4V6X Cm 78 - 127 Show 3D Structure View in InterPro
5AJ0 Am 78 - 127 Show 3D Structure View in InterPro
5LKS Lm 78 - 127 Show 3D Structure View in InterPro
5T2C g 78 - 127 Show 3D Structure View in InterPro
6IP5 2g 78 - 127 Show 3D Structure View in InterPro
6IP6 2g 78 - 127 Show 3D Structure View in InterPro
6IP8 2g 78 - 127 Show 3D Structure View in InterPro
6OLE n 78 - 127 Show 3D Structure View in InterPro
6OLF n 78 - 127 Show 3D Structure View in InterPro
6OLG Am 78 - 127 Show 3D Structure View in InterPro
6OLI n 78 - 127 Show 3D Structure View in InterPro
6OLZ Am 78 - 127 Show 3D Structure View in InterPro
6OM0 n 78 - 127 Show 3D Structure View in InterPro
6OM7 n 78 - 127 Show 3D Structure View in InterPro
6QZP Lm 78 - 127 Show 3D Structure View in InterPro
6XA1 Lm 78 - 127 Show 3D Structure View in InterPro
6Y0G Lm 78 - 127 Show 3D Structure View in InterPro
6Y2L Lm 78 - 127 Show 3D Structure View in InterPro
6Y57 Lm 78 - 127 Show 3D Structure View in InterPro
6Y6X Lm 78 - 127 Show 3D Structure View in InterPro
6Z6L Lm 78 - 127 Show 3D Structure View in InterPro
6Z6M Lm 78 - 127 Show 3D Structure View in InterPro
6Z6N Lm 78 - 127 Show 3D Structure View in InterPro
6ZM7 Lm 78 - 127 Show 3D Structure View in InterPro
6ZME Lm 78 - 127 Show 3D Structure View in InterPro
6ZMI Lm 78 - 127 Show 3D Structure View in InterPro
6ZMO Lm 78 - 127 Show 3D Structure View in InterPro
7BHP Lm 78 - 127 Show 3D Structure View in InterPro
79 - 125 6LQM R 79 - 125 Show 3D Structure View in InterPro
ubiquitin 3 - 70 5JBY B 3 - 70 Show 3D Structure View in InterPro
D 3 - 70 Show 3D Structure View in InterPro
F 3 - 70 Show 3D Structure View in InterPro
3 - 71 4P4H S 3 - 71 Show 3D Structure View in InterPro
W 3 - 71 Show 3D Structure View in InterPro
5JBV B 3 - 71 Show 3D Structure View in InterPro
3 - 72 4P4H U 3 - 72 Show 3D Structure View in InterPro
4S1Z E 3 - 72 Show 3D Structure View in InterPro
3 - 73 4P4H T 3 - 73 Show 3D Structure View in InterPro
X 3 - 73 Show 3D Structure View in InterPro
4S1Z A 3 - 73 Show 3D Structure View in InterPro
B 3 - 73 Show 3D Structure View in InterPro
C 3 - 73 Show 3D Structure View in InterPro
5GO8 B 3 - 73 Show 3D Structure View in InterPro
5GOC D 3 - 73 Show 3D Structure View in InterPro
5GOG B 3 - 73 Show 3D Structure View in InterPro
5GOH D 3 - 73 Show 3D Structure View in InterPro
5HPS B 3 - 73 Show 3D Structure View in InterPro
3 - 74 2KOX A 3 - 74 Show 3D Structure View in InterPro
2LJ5 A 3 - 74 Show 3D Structure View in InterPro
2MBH A 3 - 74 Show 3D Structure View in InterPro
2MJB A 3 - 74 Show 3D Structure View in InterPro
2MUR B 103 - 174 Show 3D Structure View in InterPro
2N3U B 3 - 74 Show 3D Structure View in InterPro
C 3 - 74 Show 3D Structure View in InterPro
2N3V B 3 - 74 Show 3D Structure View in InterPro
C 3 - 74 Show 3D Structure View in InterPro
2N3W B 3 - 74 Show 3D Structure View in InterPro
C 3 - 74 Show 3D Structure View in InterPro
2NBD A 3 - 74 Show 3D Structure View in InterPro
2NBE A 3 - 74 Show 3D Structure View in InterPro
2RSU A 3 - 74 Show 3D Structure View in InterPro
3I3T B 3 - 74 Show 3D Structure View in InterPro
D 3 - 74 Show 3D Structure View in InterPro
F 3 - 74 Show 3D Structure View in InterPro
H 3 - 74 Show 3D Structure View in InterPro
3VDZ A 103 - 174 Show 3D Structure View in InterPro
B 103 - 174 Show 3D Structure View in InterPro
4HJK A 3 - 74 Show 3D Structure View in InterPro
4JIO U 3 - 74 Show 3D Structure View in InterPro
4PIG A 3 - 74 Show 3D Structure View in InterPro
B 3 - 74 Show 3D Structure View in InterPro
C 3 - 74 Show 3D Structure View in InterPro
D 3 - 74 Show 3D Structure View in InterPro
4PIH A 3 - 74 Show 3D Structure View in InterPro
B 3 - 74 Show 3D Structure View in InterPro
4PIJ A 3 - 74 Show 3D Structure View in InterPro
B 3 - 74 Show 3D Structure View in InterPro
4RF0 B 3 - 74 Show 3D Structure View in InterPro
4RF1 B 3 - 74 Show 3D Structure View in InterPro
4S1Z D 3 - 74 Show 3D Structure View in InterPro
4XKL A 3 - 74 Show 3D Structure View in InterPro
C 3 - 74 Show 3D Structure View in InterPro
5A5B 9 3 - 74 Show 3D Structure View in InterPro
5GO7 B 3 - 74 Show 3D Structure View in InterPro
5GOB B 3 - 74 Show 3D Structure View in InterPro
5GOD C 3 - 74 Show 3D Structure View in InterPro
D 3 - 74 Show 3D Structure View in InterPro
5GOI C 3 - 74 Show 3D Structure View in InterPro
D 3 - 74 Show 3D Structure View in InterPro
5GOJ B 3 - 74 Show 3D Structure View in InterPro
5GOK B 3 - 74 Show 3D Structure View in InterPro
5HPK B 3 - 74 Show 3D Structure View in InterPro
5HPL C 3 - 74 Show 3D Structure View in InterPro
D 3 - 74 Show 3D Structure View in InterPro
5HPT B 3 - 74 Show 3D Structure View in InterPro
E 3 - 74 Show 3D Structure View in InterPro
H 3 - 74 Show 3D Structure View in InterPro
5J26 B 3 - 74 Show 3D Structure View in InterPro
5J8P A 3 - 74 Show 3D Structure View in InterPro
B 3 - 74 Show 3D Structure View in InterPro
5JBV A 3 - 74 Show 3D Structure View in InterPro
5JBY A 3 - 74 Show 3D Structure View in InterPro
C 3 - 74 Show 3D Structure View in InterPro
E 3 - 74 Show 3D Structure View in InterPro
7AY1 C 3 - 74 Show 3D Structure View in InterPro
7M3Q B 3 - 74 Show 3D Structure View in InterPro
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The parts of the structure corresponding to the Pfam family are highlighted in blue.

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TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;