Summary
This is the summary of UniProt entry RACK1_HUMAN (P63244).
Description: | Receptor of activated protein C kinase 1 |
Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
|
Length: | 317 amino acids |
Reference Proteome: |
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Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
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Source | Domain | Start | End |
---|---|---|---|
Pfam | WD40 | 5 | 44 |
Pfam | WD40 | 53 | 91 |
Pfam | WD40 | 95 | 133 |
Pfam | WD40 | 136 | 178 |
Pfam | WD40 | 182 | 220 |
Pfam | WD40 | 224 | 260 |
Pfam | WD40 | 273 | 311 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P63244. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
Sequence: | 1
MTEQMTLRGT LKGHNGWVTQ IATTPQFPDM ILSASRDKTI IMWKLTRDET
50 51
NYGIPQRALR GHSHFVSDVV ISSDGQFALS GSWDGTLRLW DLTTGTTTRR
100 101
FVGHTKDVLS VAFSSDNRQI VSGSRDKTIK LWNTLGVCKY TVQDESHSEW
150 151
VSCVRFSPNS SNPIIVSCGW DKLVKVWNLA NCKLKTNHIG HTGYLNTVTV
200 201
SPDGSLCASG GKDGQAMLWD LNEGKHLYTL DGGDIINALC FSPNRYWLCA
250 251
ATGPSIKIWD LEGKIIVDEL KQEVISTSSK AEPPQCTSLA WSADGQTLFA
300 301
GYTDNLVRVW QVTIGTR
317
Show the unformatted sequence. |
Checksums: |
CRC64:257F91E369ED2044
MD5:2301d151678d4606d30ba9e919ac4d2c
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.