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28  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RACK1_HUMAN (P63244)

Summary

This is the summary of UniProt entry RACK1_HUMAN (P63244).

Description: Receptor of activated protein C kinase 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 317 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam WD40 5 44
Pfam WD40 53 91
Pfam WD40 95 133
Pfam WD40 136 178
Pfam WD40 182 220
Pfam WD40 224 260
Pfam WD40 273 311

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P63244. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTEQMTLRGT LKGHNGWVTQ IATTPQFPDM ILSASRDKTI IMWKLTRDET
50
51
NYGIPQRALR GHSHFVSDVV ISSDGQFALS GSWDGTLRLW DLTTGTTTRR
100
101
FVGHTKDVLS VAFSSDNRQI VSGSRDKTIK LWNTLGVCKY TVQDESHSEW
150
151
VSCVRFSPNS SNPIIVSCGW DKLVKVWNLA NCKLKTNHIG HTGYLNTVTV
200
201
SPDGSLCASG GKDGQAMLWD LNEGKHLYTL DGGDIINALC FSPNRYWLCA
250
251
ATGPSIKIWD LEGKIIVDEL KQEVISTSSK AEPPQCTSLA WSADGQTLFA
300
301
GYTDNLVRVW QVTIGTR                                    
317
 

Show the unformatted sequence.

Checksums:
CRC64:257F91E369ED2044
MD5:2301d151678d4606d30ba9e919ac4d2c

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
WD40 136 - 178 4AOW A 136 - 178 Jmol OpenAstexViewer
B 136 - 178 Jmol OpenAstexViewer
C 136 - 178 Jmol OpenAstexViewer
4UG0 Sg 136 - 178 Jmol OpenAstexViewer
4V6X Ag 136 - 178 Jmol OpenAstexViewer
5A2Q g 136 - 178 Jmol OpenAstexViewer
5AJ0 Bg 136 - 178 Jmol OpenAstexViewer
5FLX g 136 - 178 Jmol OpenAstexViewer
5LKS Sg 136 - 178 Jmol OpenAstexViewer
5OA3 g 136 - 178 Jmol OpenAstexViewer
5T2C AI 136 - 178 Jmol OpenAstexViewer
5VYC g1 136 - 178 Jmol OpenAstexViewer
g2 136 - 178 Jmol OpenAstexViewer
g3 136 - 178 Jmol OpenAstexViewer
g4 136 - 178 Jmol OpenAstexViewer
g5 136 - 178 Jmol OpenAstexViewer
g6 136 - 178 Jmol OpenAstexViewer
6EK0 Sg 136 - 178 Jmol OpenAstexViewer
6FEC m 136 - 178 Jmol OpenAstexViewer
6G18 g 136 - 178 Jmol OpenAstexViewer
6G51 g 136 - 178 Jmol OpenAstexViewer
6G53 g 136 - 178 Jmol OpenAstexViewer
6G5H g 136 - 178 Jmol OpenAstexViewer
6G5I g 136 - 178 Jmol OpenAstexViewer
6IP5 3F 136 - 178 Jmol OpenAstexViewer
6IP6 3F 136 - 178 Jmol OpenAstexViewer
6IP8 3F 136 - 178 Jmol OpenAstexViewer
6OLE Sg 136 - 178 Jmol OpenAstexViewer
6OLF Sg 136 - 178 Jmol OpenAstexViewer
6OLG Bg 136 - 178 Jmol OpenAstexViewer
6OLI Sg 136 - 178 Jmol OpenAstexViewer
6OLZ Bg 136 - 178 Jmol OpenAstexViewer
6OM0 Sg 136 - 178 Jmol OpenAstexViewer
6OM7 Sg 136 - 178 Jmol OpenAstexViewer
6QZP Sg 136 - 178 Jmol OpenAstexViewer
182 - 220 4AOW A 182 - 220 Jmol OpenAstexViewer
B 182 - 220 Jmol OpenAstexViewer
C 182 - 220 Jmol OpenAstexViewer
4UG0 Sg 182 - 220 Jmol OpenAstexViewer
4V6X Ag 182 - 220 Jmol OpenAstexViewer
5A2Q g 182 - 220 Jmol OpenAstexViewer
5AJ0 Bg 182 - 220 Jmol OpenAstexViewer
5FLX g 182 - 220 Jmol OpenAstexViewer
5LKS Sg 182 - 220 Jmol OpenAstexViewer
5OA3 g 182 - 220 Jmol OpenAstexViewer
5T2C AI 182 - 220 Jmol OpenAstexViewer
5VYC g1 182 - 220 Jmol OpenAstexViewer
g2 182 - 220 Jmol OpenAstexViewer
g3 182 - 220 Jmol OpenAstexViewer
g4 182 - 220 Jmol OpenAstexViewer
g5 182 - 220 Jmol OpenAstexViewer
g6 182 - 220 Jmol OpenAstexViewer
6EK0 Sg 182 - 220 Jmol OpenAstexViewer
6FEC m 182 - 220 Jmol OpenAstexViewer
6G18 g 182 - 220 Jmol OpenAstexViewer
6G51 g 182 - 220 Jmol OpenAstexViewer
6G53 g 182 - 220 Jmol OpenAstexViewer
6G5H g 182 - 220 Jmol OpenAstexViewer
6G5I g 182 - 220 Jmol OpenAstexViewer
6IP5 3F 182 - 220 Jmol OpenAstexViewer
6IP6 3F 182 - 220 Jmol OpenAstexViewer
6IP8 3F 182 - 220 Jmol OpenAstexViewer
6OLE Sg 182 - 220 Jmol OpenAstexViewer
6OLF Sg 182 - 220 Jmol OpenAstexViewer
6OLG Bg 182 - 220 Jmol OpenAstexViewer
6OLI Sg 182 - 220 Jmol OpenAstexViewer
6OLZ Bg 182 - 220 Jmol OpenAstexViewer
6OM0 Sg 182 - 220 Jmol OpenAstexViewer
6OM7 Sg 182 - 220 Jmol OpenAstexViewer
6QZP Sg 182 - 220 Jmol OpenAstexViewer
224 - 260 4AOW A 224 - 260 Jmol OpenAstexViewer
B 224 - 260 Jmol OpenAstexViewer
C 224 - 260 Jmol OpenAstexViewer
4UG0 Sg 224 - 260 Jmol OpenAstexViewer
4V6X Ag 224 - 260 Jmol OpenAstexViewer
5A2Q g 224 - 260 Jmol OpenAstexViewer
5AJ0 Bg 224 - 260 Jmol OpenAstexViewer
5FLX g 224 - 260 Jmol OpenAstexViewer
5LKS Sg 224 - 260 Jmol OpenAstexViewer
5OA3 g 224 - 260 Jmol OpenAstexViewer
5T2C AI 224 - 260 Jmol OpenAstexViewer
5VYC g1 224 - 260 Jmol OpenAstexViewer
g2 224 - 260 Jmol OpenAstexViewer
g3 224 - 260 Jmol OpenAstexViewer
g4 224 - 260 Jmol OpenAstexViewer
g5 224 - 260 Jmol OpenAstexViewer
g6 224 - 260 Jmol OpenAstexViewer
6EK0 Sg 224 - 260 Jmol OpenAstexViewer
6FEC m 224 - 260 Jmol OpenAstexViewer
6G18 g 224 - 260 Jmol OpenAstexViewer
6G51 g 224 - 260 Jmol OpenAstexViewer
6G53 g 224 - 260 Jmol OpenAstexViewer
6G5H g 224 - 260 Jmol OpenAstexViewer
6G5I g 224 - 260 Jmol OpenAstexViewer
6IP5 3F 224 - 260 Jmol OpenAstexViewer
6IP6 3F 224 - 260 Jmol OpenAstexViewer
6IP8 3F 224 - 260 Jmol OpenAstexViewer
6OLE Sg 224 - 260 Jmol OpenAstexViewer
6OLF Sg 224 - 260 Jmol OpenAstexViewer
6OLG Bg 224 - 260 Jmol OpenAstexViewer
6OLI Sg 224 - 260 Jmol OpenAstexViewer
6OLZ Bg 224 - 260 Jmol OpenAstexViewer
6OM0 Sg 224 - 260 Jmol OpenAstexViewer
6OM7 Sg 224 - 260 Jmol OpenAstexViewer
6QZP Sg 224 - 260 Jmol OpenAstexViewer
273 - 311 4AOW A 273 - 311 Jmol OpenAstexViewer
C 273 - 311 Jmol OpenAstexViewer
4UG0 Sg 273 - 311 Jmol OpenAstexViewer
4V6X Ag 273 - 311 Jmol OpenAstexViewer
5A2Q g 273 - 311 Jmol OpenAstexViewer
5AJ0 Bg 273 - 311 Jmol OpenAstexViewer
5FLX g 273 - 311 Jmol OpenAstexViewer
5LKS Sg 273 - 311 Jmol OpenAstexViewer
5OA3 g 273 - 311 Jmol OpenAstexViewer
5T2C AI 273 - 311 Jmol OpenAstexViewer
5VYC g1 273 - 311 Jmol OpenAstexViewer
g2 273 - 311 Jmol OpenAstexViewer
g3 273 - 311 Jmol OpenAstexViewer
g4 273 - 311 Jmol OpenAstexViewer
g5 273 - 311 Jmol OpenAstexViewer
g6 273 - 311 Jmol OpenAstexViewer
6EK0 Sg 273 - 311 Jmol OpenAstexViewer
6FEC m 273 - 311 Jmol OpenAstexViewer
6G18 g 273 - 311 Jmol OpenAstexViewer
6G51 g 273 - 311 Jmol OpenAstexViewer
6G53 g 273 - 311 Jmol OpenAstexViewer
6G5H g 273 - 311 Jmol OpenAstexViewer
6G5I g 273 - 311 Jmol OpenAstexViewer
6IP5 3F 273 - 311 Jmol OpenAstexViewer
6IP6 3F 273 - 311 Jmol OpenAstexViewer
6IP8 3F 273 - 311 Jmol OpenAstexViewer
6OLE Sg 273 - 311 Jmol OpenAstexViewer
6OLF Sg 273 - 311 Jmol OpenAstexViewer
6OLG Bg 273 - 311 Jmol OpenAstexViewer
6OLI Sg 273 - 311 Jmol OpenAstexViewer
6OLZ Bg 273 - 311 Jmol OpenAstexViewer
6OM0 Sg 273 - 311 Jmol OpenAstexViewer
6OM7 Sg 273 - 311 Jmol OpenAstexViewer
6QZP Sg 273 - 311 Jmol OpenAstexViewer
283 - 311 4AOW B 283 - 311 Jmol OpenAstexViewer
5 - 44 4AOW A 5 - 44 Jmol OpenAstexViewer
B 5 - 44 Jmol OpenAstexViewer
C 5 - 44 Jmol OpenAstexViewer
4UG0 Sg 5 - 44 Jmol OpenAstexViewer
4V6X Ag 5 - 44 Jmol OpenAstexViewer
5A2Q g 5 - 44 Jmol OpenAstexViewer
5AJ0 Bg 5 - 44 Jmol OpenAstexViewer
5FLX g 5 - 44 Jmol OpenAstexViewer
5LKS Sg 5 - 44 Jmol OpenAstexViewer
5OA3 g 5 - 44 Jmol OpenAstexViewer
5T2C AI 5 - 44 Jmol OpenAstexViewer
5VYC g1 5 - 44 Jmol OpenAstexViewer
g2 5 - 44 Jmol OpenAstexViewer
g3 5 - 44 Jmol OpenAstexViewer
g4 5 - 44 Jmol OpenAstexViewer
g5 5 - 44 Jmol OpenAstexViewer
g6 5 - 44 Jmol OpenAstexViewer
6EK0 Sg 5 - 44 Jmol OpenAstexViewer
6FEC m 5 - 44 Jmol OpenAstexViewer
6G18 g 5 - 44 Jmol OpenAstexViewer
6G51 g 5 - 44 Jmol OpenAstexViewer
6G53 g 5 - 44 Jmol OpenAstexViewer
6G5H g 5 - 44 Jmol OpenAstexViewer
6G5I g 5 - 44 Jmol OpenAstexViewer
6IP5 3F 5 - 44 Jmol OpenAstexViewer
6IP6 3F 5 - 44 Jmol OpenAstexViewer
6IP8 3F 5 - 44 Jmol OpenAstexViewer
6OLE Sg 5 - 44 Jmol OpenAstexViewer
6OLF Sg 5 - 44 Jmol OpenAstexViewer
6OLG Bg 5 - 44 Jmol OpenAstexViewer
6OLI Sg 5 - 44 Jmol OpenAstexViewer
6OLZ Bg 5 - 44 Jmol OpenAstexViewer
6OM0 Sg 5 - 44 Jmol OpenAstexViewer
6OM7 Sg 5 - 44 Jmol OpenAstexViewer
6QZP Sg 5 - 44 Jmol OpenAstexViewer
53 - 91 4AOW A 53 - 91 Jmol OpenAstexViewer
B 53 - 91 Jmol OpenAstexViewer
C 53 - 91 Jmol OpenAstexViewer
4UG0 Sg 53 - 91 Jmol OpenAstexViewer
4V6X Ag 53 - 91 Jmol OpenAstexViewer
5A2Q g 53 - 91 Jmol OpenAstexViewer
5AJ0 Bg 53 - 91 Jmol OpenAstexViewer
5FLX g 53 - 91 Jmol OpenAstexViewer
5LKS Sg 53 - 91 Jmol OpenAstexViewer
5OA3 g 53 - 91 Jmol OpenAstexViewer
5T2C AI 53 - 91 Jmol OpenAstexViewer
5VYC g1 53 - 91 Jmol OpenAstexViewer
g2 53 - 91 Jmol OpenAstexViewer
g3 53 - 91 Jmol OpenAstexViewer
g4 53 - 91 Jmol OpenAstexViewer
g5 53 - 91 Jmol OpenAstexViewer
g6 53 - 91 Jmol OpenAstexViewer
6EK0 Sg 53 - 91 Jmol OpenAstexViewer
6FEC m 53 - 91 Jmol OpenAstexViewer
6G18 g 53 - 91 Jmol OpenAstexViewer
6G51 g 53 - 91 Jmol OpenAstexViewer
6G53 g 53 - 91 Jmol OpenAstexViewer
6G5H g 53 - 91 Jmol OpenAstexViewer
6G5I g 53 - 91 Jmol OpenAstexViewer
6IP5 3F 53 - 91 Jmol OpenAstexViewer
6IP6 3F 53 - 91 Jmol OpenAstexViewer
6IP8 3F 53 - 91 Jmol OpenAstexViewer
6OLE Sg 53 - 91 Jmol OpenAstexViewer
6OLF Sg 53 - 91 Jmol OpenAstexViewer
6OLG Bg 53 - 91 Jmol OpenAstexViewer
6OLI Sg 53 - 91 Jmol OpenAstexViewer
6OLZ Bg 53 - 91 Jmol OpenAstexViewer
6OM0 Sg 53 - 91 Jmol OpenAstexViewer
6OM7 Sg 53 - 91 Jmol OpenAstexViewer
6QZP Sg 53 - 91 Jmol OpenAstexViewer
95 - 133 4AOW A 95 - 133 Jmol OpenAstexViewer
B 95 - 133 Jmol OpenAstexViewer
C 95 - 133 Jmol OpenAstexViewer
4UG0 Sg 95 - 133 Jmol OpenAstexViewer
4V6X Ag 95 - 133 Jmol OpenAstexViewer
5A2Q g 95 - 133 Jmol OpenAstexViewer
5AJ0 Bg 95 - 133 Jmol OpenAstexViewer
5FLX g 95 - 133 Jmol OpenAstexViewer
5LKS Sg 95 - 133 Jmol OpenAstexViewer
5OA3 g 95 - 133 Jmol OpenAstexViewer
5T2C AI 95 - 133 Jmol OpenAstexViewer
5VYC g1 95 - 133 Jmol OpenAstexViewer
g2 95 - 133 Jmol OpenAstexViewer
g3 95 - 133 Jmol OpenAstexViewer
g4 95 - 133 Jmol OpenAstexViewer
g5 95 - 133 Jmol OpenAstexViewer
g6 95 - 133 Jmol OpenAstexViewer
6EK0 Sg 95 - 133 Jmol OpenAstexViewer
6FEC m 95 - 133 Jmol OpenAstexViewer
6G18 g 95 - 133 Jmol OpenAstexViewer
6G51 g 95 - 133 Jmol OpenAstexViewer
6G53 g 95 - 133 Jmol OpenAstexViewer
6G5H g 95 - 133 Jmol OpenAstexViewer
6G5I g 95 - 133 Jmol OpenAstexViewer
6IP5 3F 95 - 133 Jmol OpenAstexViewer
6IP6 3F 95 - 133 Jmol OpenAstexViewer
6IP8 3F 95 - 133 Jmol OpenAstexViewer
6OLE Sg 95 - 133 Jmol OpenAstexViewer
6OLF Sg 95 - 133 Jmol OpenAstexViewer
6OLG Bg 95 - 133 Jmol OpenAstexViewer
6OLI Sg 95 - 133 Jmol OpenAstexViewer
6OLZ Bg 95 - 133 Jmol OpenAstexViewer
6OM0 Sg 95 - 133 Jmol OpenAstexViewer
6OM7 Sg 95 - 133 Jmol OpenAstexViewer
6QZP Sg 95 - 133 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.