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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: PA1B2_HUMAN (P68402)

Summary

This is the summary of UniProt entry PA1B2_HUMAN (P68402).

Description: Platelet-activating factor acetylhydrolase IB subunit beta EC=3.1.1.47
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 229 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 19
Pfam Lipase_GDSL_2 44 204
disorder n/a 150 151
disorder n/a 224 229

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P68402. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSQGDSNPAA IPHAAEDIQG DDRWMSQHNR FVLDCKDKEP DVLFVGDSMV
50
51
QLMQQYEIWR ELFSPLHALN FGIGGDTTRH VLWRLKNGEL ENIKPKVIVV
100
101
WVGTNNHENT AEEVAGGIEA IVQLINTRQP QAKIIVLGLL PRGEKPNPLR
150
151
QKNAKVNQLL KVSLPKLANV QLLDTDGGFV HSDGAISCHD MFDFLHLTGG
200
201
GYAKICKPLH ELIMQLLEET PEEKQTTIA                       
229
 

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Checksums:
CRC64:14CF5D48621AA504
MD5:4b1a824cc45d5663861ab0e0542216cc

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Lipase_GDSL_2 44 - 204 1VYH A 44 - 204 Jmol OpenAstexViewer
B 44 - 204 Jmol OpenAstexViewer
E 44 - 204 Jmol OpenAstexViewer
F 44 - 204 Jmol OpenAstexViewer
I 44 - 204 Jmol OpenAstexViewer
J 44 - 204 Jmol OpenAstexViewer
M 44 - 204 Jmol OpenAstexViewer
N 44 - 204 Jmol OpenAstexViewer
Q 44 - 204 Jmol OpenAstexViewer
R 44 - 204 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.