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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: NHAP2_ECOLI (P76007)

Summary

This is the summary of UniProt entry NHAP2_ECOLI (P76007).

Description: K(+)/H(+) antiporter NhaP2 {ECO:0000255|HAMAP-Rule:MF_01075}
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
Length: 578 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
transmembrane n/a 6 23
Pfam Na_H_Exchanger 10 389
low_complexity n/a 11 32
transmembrane n/a 30 47
transmembrane n/a 59 76
transmembrane n/a 88 113
transmembrane n/a 119 141
transmembrane n/a 162 179
transmembrane n/a 191 210
low_complexity n/a 191 211
transmembrane n/a 217 237
low_complexity n/a 217 231
transmembrane n/a 243 261
transmembrane n/a 273 292
low_complexity n/a 292 307
transmembrane n/a 298 323
transmembrane n/a 335 357
transmembrane n/a 363 381
low_complexity n/a 363 378
low_complexity n/a 386 405
Pfam TrkA_C 417 484
Pfam CorC_HlyC 492 573

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P76007. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDATTIISLF ILGSILVTSS ILLSSFSSRL GIPILVIFLA IGMLAGVDGV
50
51
GGIPFDNYPF AYMVSNLALA IILLDGGMRT QASSFRVALG PALSLATLGV
100
101
LITSGLTGMM AAWLFNLDLI EGLLIGAIVG STDAAAVFSL LGGKGLNERV
150
151
GSTLEIESGS NDPMAVFLTI TLIAMIQHHE SNISWMFIVD ILQQFGLGIV
200
201
IGLGGGYLLL QMINRIALPA GLYPLLALSG GILIFSLTTA LEGSGILAVY
250
251
LCGFLLGNRP IRNRYGILQN FDGLAWLAQI AMFLVLGLLV NPSDLLPIAI
300
301
PALILSAWMI FFARPLSVFA GLLPFRGFNL RERVFISWVG LRGAVPIILA
350
351
VFPMMAGLEN ARLFFNVAFF VVLVSLLLQG TSLSWAAKKA KVVVPPVGRP
400
401
VSRVGLDIHP ENPWEQFVYQ LSADKWCVGA ALRDLHMPKE TRIAALFRDN
450
451
QLLHPTGSTR LREGDVLCVI GRERDLPALG KLFSQSPPVA LDQRFFGDFI
500
501
LEASAKYADV ALIYGLEDGR EYRDKQQTLG EIVQQLLGAA PVVGDQVEFA
550
551
GMIWTVAEKE DNEVLKIGVR VAEEEAES                        
578
 

Show the unformatted sequence.

Checksums:
CRC64:4637F874E527334A
MD5:00022ccf4f592481b9b6b360503916ec

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;