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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PAOA_ECOLI (P77165)

Summary

This is the summary of UniProt entry PAOA_ECOLI (P77165).

Description: Aldehyde oxidoreductase iron-sulfur-binding subunit PaoA {ECO:0000305}
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
Length: 229 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 21
low_complexity n/a 33 41
disorder n/a 60 62
disorder n/a 64 66
Pfam Fer2 65 126
disorder n/a 77 78
low_complexity n/a 77 87
Pfam Fer2_2 133 221
disorder n/a 135 137

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P77165. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSNQGEYPED NRVGKHEPHD LSLTRRDLIK VSAATAATAV VYPHSTLAAS
50
51
VPAATPAPEI MPLTLKVNGK TEQLEVDTRT TLLDTLRENL HLIGTKKGCD
100
101
HGQCGACTVL VNGRRLNACL TLAVMHQGAE ITTIEGLGSP DNLHPMQAAF
150
151
IKHDGFQCGY CTSGQICSSV AVLKEIQDGI PSHVTVDLVS APETTADEIR
200
201
ERMSGNICRC GAYANILAAI EDAAGEIKS                       
229
 

Show the unformatted sequence.

Checksums:
CRC64:216961D7BD21836C
MD5:5cc5ee9665ec3b972d55c960e92d608d

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Fer2 65 - 126 5G5G A 65 - 126 Show 3D Structure View in InterPro
5G5H A 65 - 126 Show 3D Structure View in InterPro
Fer2_2 133 - 221 5G5G A 133 - 221 Show 3D Structure View in InterPro
5G5H A 133 - 221 Show 3D Structure View in InterPro
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The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;