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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ALKA_MYCTU (P9WJW3)

Summary

This is the summary of UniProt entry ALKA_MYCTU (P9WJW3).

Description: Probable bifunctional transcriptional activator/DNA repair enzyme AlkA Methylphosphotriester-DNA--protein-cysteine S-methyltransferase DNA-3-methyladenine glycosylase EC=2.1.1.n11 EC=3.2.2.21
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (NCBI taxonomy ID 83332)
Length: 496 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam Ada_Zn_binding 7 71
low_complexity n/a 180 197
Pfam AlkA_N 201 316
Pfam HhH-GPD 322 472
low_complexity n/a 442 453
disorder n/a 490 496

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P9WJW3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MHDDFERCYR AIQSKDARFD GWFVVAVLTT GVYCRPSCPV RPPFARNVRF
50
51
LPTAAAAQGE GFRACKRCRP DASPGSPEWN VRSDVVARAM RLIADGTVDR
100
101
DGVSGLAAQL GYTIRQLERL LQAVVGAGPL ALARAQRMQT ARVLIETTNL
150
151
PFGDVAFAAG FSSIRQFNDT VRLACDGTPT ALRARAAARF ESATASAGTV
200
201
SLRLPVRAPF AFEGVFGHLA ATAVPGCEEV RDGAYRRTLR LPWGNGIVSL
250
251
TPAPDHVRCL LVLDDFRDLM TATARCRRLL DLDADPEAIV EALGADPDLR
300
301
AVVGKAPGQR IPRTVDEAEF AVRAVLAQQV STKAASTHAG RLVAAYGRPV
350
351
HDRHGALTHT FPSIEQLAEI DPGHLAVPKA RQRTINALVA SLADKSLVLD
400
401
AGCDWQRARG QLLALPGVGP WTAEVIAMRG LGDPDAFPAS DLGLRLAAKK
450
451
LGLPAQRRAL TVHSARWRPW RSYATQHLWT TLEHPVNQWP PQEKIA    
496
 

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Checksums:
CRC64:CA1F52032181268F
MD5:2c41d8e623d85e02015e732cb0e7749e

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;