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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: COX1_MYCTU (P9WP71)

Summary

This is the summary of UniProt entry COX1_MYCTU (P9WP71).

Description: Probable cytochrome c oxidase subunit 1 EC=7.1.1.9
Source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (NCBI taxonomy ID 83332)
Length: 573 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam COX1 39 483
transmembrane n/a 40 62
transmembrane n/a 82 109
transmembrane n/a 121 141
transmembrane n/a 170 196
transmembrane n/a 208 234
transmembrane n/a 254 278
transmembrane n/a 290 311
transmembrane n/a 317 339
transmembrane n/a 360 380
low_complexity n/a 363 379
transmembrane n/a 400 418
transmembrane n/a 430 452
transmembrane n/a 472 493
disorder n/a 530 531
disorder n/a 565 573

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P9WP71. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTAEAPPLGE LEAIRPYPAR TGPKGSLVYK LITTTDHKMI GIMYCVACIS
50
51
FFFIGGLLAL LMRTELAAPG LQFLSNEQFN QLFTMHGTIM LLFYATPIVF
100
101
GFANLVLPLQ IGAPDVAFPR LNAFSFWLFV FGATIGAAGF ITPGGAADFG
150
151
WTAYTPLTDA IHSPGAGGDL WIMGLIVAGL GTILGAVNMI TTVVCMRAPG
200
201
MTMFRMPIFT WNIMVTSILI LIAFPLLTAA LFGLAADRHL GAHIYDAANG
250
251
GVLLWQHLFW FFGHPEVYII ALPFFGIVSE IFPVFSRKPI FGYTTLVYAT
300
301
LSIAALSVAV WAHHMFATGA VLLPFFSFMT YLIAVPTGIK FFNWIGTMWK
350
351
GQLTFETPML FSVGFMVTFL LGGLTGVLLA SPPLDFHVTD SYFVVAHFHY
400
401
VLFGTIVFAT FAGIYFWFPK MTGRLLDERL GKLHFWLTFI GFHTTFLVQH
450
451
WLGDEGMPRR YADYLPTDGF QGLNVVSTIG AFILGASMFP FVWNVFKSWR
500
501
YGEVVTVDDP WGYGNSLEWA TSCPPPRHNF TELPRIRSER PAFELHYPHM
550
551
VERLRAEAHV GRHHDEPAMV TSS                             
573
 

Show the unformatted sequence.

Checksums:
CRC64:9B0F91666F482BEE
MD5:8421535ba5dd0d592f5ebd6c615737c0

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;