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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CAC1D_HUMAN (Q01668)

Summary

This is the summary of UniProt entry CAC1D_HUMAN (Q01668).

Description: Voltage-dependent L-type calcium channel subunit alpha-1D
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 2161 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
low_complexity n/a 0 9
disorder n/a 1 49
low_complexity n/a 53 66
disorder n/a 64 95
Pfam Ion_trans 125 417
transmembrane n/a 130 147
transmembrane n/a 167 187
transmembrane n/a 199 218
transmembrane n/a 271 294
transmembrane n/a 350 371
transmembrane n/a 383 405
disorder n/a 449 480
low_complexity n/a 450 459
low_complexity n/a 502 516
Pfam Ion_trans 522 762
transmembrane n/a 523 541
transmembrane n/a 561 584
low_complexity n/a 634 645
low_complexity n/a 648 666
transmembrane n/a 653 672
transmembrane n/a 725 752
coiled_coil n/a 755 786
disorder n/a 761 848
low_complexity n/a 765 780
low_complexity n/a 818 839
disorder n/a 850 854
Pfam Ion_trans 885 1163
transmembrane n/a 887 905
transmembrane n/a 925 945
transmembrane n/a 957 983
low_complexity n/a 978 992
transmembrane n/a 1003 1033
low_complexity n/a 1127 1141
transmembrane n/a 1130 1155
Pfam Ion_trans 1204 1475
transmembrane n/a 1209 1227
transmembrane n/a 1239 1259
disorder n/a 1295 1303
transmembrane n/a 1349 1367
low_complexity n/a 1379 1387
transmembrane n/a 1441 1464
Pfam GPHH 1484 1537
Pfam Ca_chan_IQ 1547 1621
coiled_coil n/a 1559 1579
Pfam CAC1F_C 1642 1962
disorder n/a 1656 1812
low_complexity n/a 1663 1676
low_complexity n/a 1737 1743
disorder n/a 1817 1827
disorder n/a 1852 1853
disorder n/a 1863 1864
disorder n/a 1871 1893
disorder n/a 1895 1898
disorder n/a 1901 1915
low_complexity n/a 1901 1912
disorder n/a 1922 1925
disorder n/a 1936 1946
disorder n/a 1963 1985
Pfam CAC1F_C 1965 2160
disorder n/a 2008 2009
disorder n/a 2011 2012
disorder n/a 2019 2020
disorder n/a 2044 2055
disorder n/a 2058 2061
disorder n/a 2103 2154
low_complexity n/a 2138 2149

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q01668. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MMMMMMMKKM QHQRQQQADH ANEANYARGT RLPLSGEGPT SQPNSSKQTV
50
51
LSWQAAIDAA RQAKAAQTMS TSAPPPVGSL SQRKRQQYAK SKKQGNSSNS
100
101
RPARALFCLS LNNPIRRACI SIVEWKPFDI FILLAIFANC VALAIYIPFP
150
151
EDDSNSTNHN LEKVEYAFLI IFTVETFLKI IAYGLLLHPN AYVRNGWNLL
200
201
DFVIVIVGLF SVILEQLTKE TEGGNHSSGK SGGFDVKALR AFRVLRPLRL
250
251
VSGVPSLQVV LNSIIKAMVP LLHIALLVLF VIIIYAIIGL ELFIGKMHKT
300
301
CFFADSDIVA EEDPAPCAFS GNGRQCTANG TECRSGWVGP NGGITNFDNF
350
351
AFAMLTVFQC ITMEGWTDVL YWMNDAMGFE LPWVYFVSLV IFGSFFVLNL
400
401
VLGVLSGEFS KEREKAKARG DFQKLREKQQ LEEDLKGYLD WITQAEDIDP
450
451
ENEEEGGEEG KRNTSMPTSE TESVNTENVS GEGENRGCCG SLCQAISKSK
500
501
LSRRWRRWNR FNRRRCRAAV KSVTFYWLVI VLVFLNTLTI SSEHYNQPDW
550
551
LTQIQDIANK VLLALFTCEM LVKMYSLGLQ AYFVSLFNRF DCFVVCGGIT
600
601
ETILVELEIM SPLGISVFRC VRLLRIFKVT RHWTSLSNLV ASLLNSMKSI
650
651
ASLLLLLFLF IIIFSLLGMQ LFGGKFNFDE TQTKRSTFDN FPQALLTVFQ
700
701
ILTGEDWNAV MYDGIMAYGG PSSSGMIVCI YFIILFICGN YILLNVFLAI
750
751
AVDNLADAES LNTAQKEEAE EKERKKIARK ESLENKKNNK PEVNQIANSD
800
801
NKVTIDDYRE EDEDKDPYPP CDVPVGEEEE EEEEDEPEVP AGPRPRRISE
850
851
LNMKEKIAPI PEGSAFFILS KTNPIRVGCH KLINHHIFTN LILVFIMLSS
900
901
AALAAEDPIR SHSFRNTILG YFDYAFTAIF TVEILLKMTT FGAFLHKGAF
950
951
CRNYFNLLDM LVVGVSLVSF GIQSSAISVV KILRVLRVLR PLRAINRAKG
1000
1001
LKHVVQCVFV AIRTIGNIMI VTTLLQFMFA CIGVQLFKGK FYRCTDEAKS
1050
1051
NPEECRGLFI LYKDGDVDSP VVRERIWQNS DFNFDNVLSA MMALFTVSTF
1100
1101
EGWPALLYKA IDSNGENIGP IYNHRVEISI FFIIYIIIVA FFMMNIFVGF
1150
1151
VIVTFQEQGE KEYKNCELDK NQRQCVEYAL KARPLRRYIP KNPYQYKFWY
1200
1201
VVNSSPFEYM MFVLIMLNTL CLAMQHYEQS KMFNDAMDIL NMVFTGVFTV
1250
1251
EMVLKVIAFK PKGYFSDAWN TFDSLIVIGS IIDVALSEAD PTESENVPVP
1300
1301
TATPGNSEES NRISITFFRL FRVMRLVKLL SRGEGIRTLL WTFIKSFQAL
1350
1351
PYVALLIAML FFIYAVIGMQ MFGKVAMRDN NQINRNNNFQ TFPQAVLLLF
1400
1401
RCATGEAWQE IMLACLPGKL CDPESDYNPG EEYTCGSNFA IVYFISFYML
1450
1451
CAFLIINLFV AVIMDNFDYL TRDWSILGPH HLDEFKRIWS EYDPEAKGRI
1500
1501
KHLDVVTLLR RIQPPLGFGK LCPHRVACKR LVAMNMPLNS DGTVMFNATL
1550
1551
FALVRTALKI KTEGNLEQAN EELRAVIKKI WKKTSMKLLD QVVPPAGDDE
1600
1601
VTVGKFYATF LIQDYFRKFK KRKEQGLVGK YPAKNTTIAL QAGLRTLHDI
1650
1651
GPEIRRAISC DLQDDEPEET KREEEDDVFK RNGALLGNHV NHVNSDRRDS
1700
1701
LQQTNTTHRP LHVQRPSIPP ASDTEKPLFP PAGNSVCHNH HNHNSIGKQV
1750
1751
PTSTNANLNN ANMSKAAHGK RPSIGNLEHV SENGHHSSHK HDREPQRRSS
1800
1801
VKRTRYYETY IRSDSGDEQL PTICREDPEI HGYFRDPHCL GEQEYFSSEE
1850
1851
CYEDDSSPTW SRQNYGYYSR YPGRNIDSER PRGYHHPQGF LEDDDSPVCY
1900
1901
DSRRSPRRRL LPPTPASHRR SSFNFECLRR QSSQEEVPSS PIFPHRTALP
1950
1951
LHLMQQQIMA VAGLDSSKAQ KYSPSHSTRS WATPPATPPY RDWTPCYTPL
2000
2001
IQVEQSEALD QVNGSLPSLH RSSWYTDEPD ISYRTFTPAS LTVPSSFRNK
2050
2051
NSDKQRSADS LVEAVLISEG LGRYARDPKF VSATKHEIAD ACDLTIDEME
2100
2101
SAASTLLNGN VRPRANGDVG PLSHRQDYEL QDFGPGYSDE EPDPGRDEED
2150
2151
LADEMICITT L                                          
2161
 

Show the unformatted sequence.

Checksums:
CRC64:31B0ADFCDB30B575
MD5:6fe656fa31d6b665f84f69074699f390

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.