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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: REL_HUMAN (Q04864)

Summary

This is the summary of UniProt entry REL_HUMAN (Q04864).

Description: Proto-oncogene c-Rel
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 619 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam RHD_DNA_bind 10 178
disorder n/a 32 44
disorder n/a 76 77
Pfam RHD_dimer 187 283
disorder n/a 261 265
disorder n/a 274 276
low_complexity n/a 290 305
disorder n/a 315 330
disorder n/a 332 348
disorder n/a 351 355
disorder n/a 371 375
disorder n/a 378 393
low_complexity n/a 386 399
disorder n/a 398 402
low_complexity n/a 402 420
disorder n/a 407 437
disorder n/a 442 449
disorder n/a 477 478
disorder n/a 481 482
disorder n/a 494 522
disorder n/a 526 544
low_complexity n/a 539 553
disorder n/a 547 550
disorder n/a 567 600
disorder n/a 602 604

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q04864. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MASGAYNPYI EIIEQPRQRG MRFRYKCEGR SAGSIPGEHS TDNNRTYPSI
50
51
QIMNYYGKGK VRITLVTKND PYKPHPHDLV GKDCRDGYYE AEFGQERRPL
100
101
FFQNLGIRCV KKKEVKEAII TRIKAGINPF NVPEKQLNDI EDCDLNVVRL
150
151
CFQVFLPDEH GNLTTALPPV VSNPIYDNRA PNTAELRICR VNKNCGSVRG
200
201
GDEIFLLCDK VQKDDIEVRF VLNDWEAKGI FSQADVHRQV AIVFKTPPYC
250
251
KAITEPVTVK MQLRRPSDQE VSESMDFRYL PDEKDTYGNK AKKQKTTLLF
300
301
QKLCQDHVET GFRHVDQDGL ELLTSGDPPT LASQSAGITV NFPERPRPGL
350
351
LGSIGEGRYF KKEPNLFSHD AVVREMPTGV SSQAESYYPS PGPISSGLSH
400
401
HASMAPLPSS SWSSVAHPTP RSGNTNPLSS FSTRTLPSNS QGIPPFLRIP
450
451
VGNDLNASNA CIYNNADDIV GMEASSMPSA DLYGISDPNM LSNCSVNMMT
500
501
TSSDSMGETD NPRLLSMNLE NPSCNSVLDP RDLRQLHQMS SSSMSAGANS
550
551
NTTVFVSQSD AFEGSDFSCA DNSMINESGP SNSTNPNSHG FVQDSQYSGI
600
601
GSMQNEQLSD SFPYEFFQV                                  
619
 

Show the unformatted sequence.

Checksums:
CRC64:03E1033BDF7B1B30
MD5:f9722b5390360f4bfa652764ce5cdf89

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;