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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ZBT16_HUMAN (Q05516)

Summary

This is the summary of UniProt entry ZBT16_HUMAN (Q05516).

Description: Zinc finger and BTB domain-containing protein 16
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 673 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam BTB 24 126
low_complexity n/a 101 115
disorder n/a 129 145
disorder n/a 168 195
disorder n/a 204 336
disorder n/a 344 350
Pfam zf-C2H2_6 460 485
disorder n/a 477 479
Pfam zf-C2H2 491 512
Pfam zf-C2H2_6 517 542
Pfam zf-C2H2 546 568
Pfam zf-C2H2 574 596
disorder n/a 650 651
disorder n/a 653 655

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q05516. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDLTKMGMIQ LQNPSHPTGL LCKANQMRLA GTLCDVVIMV DSQEFHAHRT
50
51
VLACTSKMFE ILFHRNSQHY TLDFLSPKTF QQILEYAYTA TLQAKAEDLD
100
101
DLLYAAEILE IEYLEEQCLK MLETIQASDD NDTEATMADG GAEEEEDRKA
150
151
RYLKNIFISK HSSEESGYAS VAGQSLPGPM VDQSPSVSTS FGLSAMSPTK
200
201
AAVDSLMTIG QSLLQGTLQP PAGPEEPTLA GGGRHPGVAE VKTEMMQVDE
250
251
VPSQDSPGAA ESSISGGMGD KVEERGKEGP GTPTRSSVIT SARELHYGRE
300
301
ESAEQVPPPA EAGQAPTGRP EHPAPPPEKH LGIYSVLPNH KADAVLSMPS
350
351
SVTSGLHVQP ALAVSMDFST YGGLLPQGFI QRELFSKLGE LAVGMKSESR
400
401
TIGEQCSVCG VELPDNEAVE QHRKLHSGMK TYGCELCGKR FLDSLRLRMH
450
451
LLAHSAGAKA FVCDQCGAQF SKEDALETHR QTHTGTDMAV FCLLCGKRFQ
500
501
AQSALQQHME VHAGVRSYIC SECNRTFPSH TALKRHLRSH TGDHPYECEF
550
551
CGSCFRDEST LKSHKRIHTG EKPYECNGCG KKFSLKHQLE THYRVHTGEK
600
601
PFECKLCHQR SRDYSAMIKH LRTHNGASPY QCTICTEYCP SLSSMQKHMK
650
651
GHKPEEIPPD WRIEKTYLYL CYV                             
673
 

Show the unformatted sequence.

Checksums:
CRC64:51F8E361FA31239E
MD5:e729dc8a8f9de1b0f12caedb44f0f828

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
BTB 24 - 122 1CS3 A 24 - 122 Jmol OpenAstexViewer
24 - 126 1BUO A 24 - 126 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.