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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SUH_HUMAN (Q06330)

Summary

This is the summary of UniProt entry SUH_HUMAN (Q06330).

Description: Recombining binding protein suppressor of hairless
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 500 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 38
low_complexity n/a 4 19
Pfam LAG1-DNAbind 48 178
disorder n/a 85 91
Pfam BTD 179 328
low_complexity n/a 345 356
disorder n/a 447 448
disorder n/a 453 499
low_complexity n/a 481 499

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q06330. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDHTEGSPAE EPPAHAPSPG KFGERPPPKR LTREAMRNYL KERGDQTVLI
50
51
LHAKVAQKSY GNEKRFFCPP PCVYLMGSGW KKKKEQMERD GCSEQESQPC
100
101
AFIGIGNSDQ EMQQLNLEGK NYCTAKTLYI SDSDKRKHFM LSVKMFYGNS
150
151
DDIGVFLSKR IKVISKPSKK KQSLKNADLC IASGTKVALF NRLRSQTVST
200
201
RYLHVEGGNF HASSQQWGAF FIHLLDDDES EGEEFTVRDG YIHYGQTVKL
250
251
VCSVTGMALP RLIIRKVDKQ TALLDADDPV SQLHKCAFYL KDTERMYLCL
300
301
SQERIIQFQA TPCPKEPNKE MINDGASWTI ISTDKAEYTF YEGMGPVLAP
350
351
VTPVPVVESL QLNGGGDVAM LELTGQNFTP NLRVWFGDVE AETMYRCGES
400
401
MLCVVPDISA FREGWRWVRQ PVQVPVTLVR NDGIIYSTSL TFTYTPEPGP
450
451
RPHCSAAGAI LRANSSQVPP NESNTNSEGS YTNASTNSTS VTSSTATVVS
500
501
                                                      
500
 

Show the unformatted sequence.

Checksums:
CRC64:91E50D2DE9087EDA
MD5:a212fd7779d0a8a990af36e8319ace36

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
BTD 179 - 328 2F8X C 165 - 314 Jmol OpenAstexViewer
3NBN A 165 - 314 Jmol OpenAstexViewer
D 165 - 314 Jmol OpenAstexViewer
3V79 C 165 - 314 Jmol OpenAstexViewer
LAG1-DNAbind 48 - 178 2F8X C 34 - 164 Jmol OpenAstexViewer
3NBN A 34 - 164 Jmol OpenAstexViewer
D 34 - 164 Jmol OpenAstexViewer
3V79 C 34 - 164 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.