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67  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: B2CL1_HUMAN (Q07817)

Summary

This is the summary of UniProt entry B2CL1_HUMAN (Q07817).

Description: Bcl-2-like protein 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 233 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam BH4 1 26
disorder n/a 27 58
disorder n/a 60 63
Pfam Bcl-2 90 188
transmembrane n/a 213 231

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q07817. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSQSNRELVV DFLSYKLSQK GYSWSQFSDV EENRTEAPEG TESEMETPSA
50
51
INGNPSWHLA DSPAVNGATG HSSSLDAREV IPMAAVKQAL REAGDEFELR
100
101
YRRAFSDLTS QLHITPGTAY QSFEQVVNEL FRDGVNWGRI VAFFSFGGAL
150
151
CVESVDKEMQ VLVSRIAAWM ATYLNDHLEP WIQENGGWDT FVELYGNNAA
200
201
AESRKGQERF NRWFLTGMTV AGVVLLGSLF SRK                  
233
 

Show the unformatted sequence.

Checksums:
CRC64:E09D3CDD851AE9BE
MD5:f72151617ea1b327823c13fe9e86af8d

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Bcl-2 168 - 188 5C3G A 168 - 188 Jmol OpenAstexViewer
90 - 101 4CIN D 12 - 23 Jmol OpenAstexViewer
90 - 102 4CIN C 12 - 24 Jmol OpenAstexViewer
90 - 188 1BXL A 90 - 188 Jmol OpenAstexViewer
1G5J A 94 - 192 Jmol OpenAstexViewer
1LXL A 90 - 188 Jmol OpenAstexViewer
1MAZ A 90 - 188 Jmol OpenAstexViewer
1R2D A 90 - 188 Jmol OpenAstexViewer
1R2E A 90 - 188 Jmol OpenAstexViewer
1R2G A 90 - 188 Jmol OpenAstexViewer
1R2H A 90 - 188 Jmol OpenAstexViewer
1R2I A 90 - 188 Jmol OpenAstexViewer
1YSG A 94 - 192 Jmol OpenAstexViewer
1YSI A 94 - 192 Jmol OpenAstexViewer
1YSN A 94 - 192 Jmol OpenAstexViewer
2B48 A 90 - 188 Jmol OpenAstexViewer
2LP8 A 50 - 148 Jmol OpenAstexViewer
2LPC A 50 - 148 Jmol OpenAstexViewer
2M03 A 54 - 152 Jmol OpenAstexViewer
2M04 A 90 - 188 Jmol OpenAstexViewer
2ME8 A 93 - 191 Jmol OpenAstexViewer
2ME9 A 93 - 191 Jmol OpenAstexViewer
2MEJ A 93 - 191 Jmol OpenAstexViewer
2O1Y A 94 - 192 Jmol OpenAstexViewer
2O2M A 94 - 192 Jmol OpenAstexViewer
2O2N A 94 - 192 Jmol OpenAstexViewer
2P1L A 90 - 188 Jmol OpenAstexViewer
C 90 - 188 Jmol OpenAstexViewer
E 90 - 188 Jmol OpenAstexViewer
G 90 - 188 Jmol OpenAstexViewer
2PON B 106 - 204 Jmol OpenAstexViewer
2YJ1 A 90 - 188 Jmol OpenAstexViewer
C 90 - 188 Jmol OpenAstexViewer
2YQ6 A 90 - 188 Jmol OpenAstexViewer
2YQ7 A 90 - 188 Jmol OpenAstexViewer
2YXJ A 90 - 188 Jmol OpenAstexViewer
B 90 - 188 Jmol OpenAstexViewer
3CVA X 90 - 188 Jmol OpenAstexViewer
3FDL A 90 - 188 Jmol OpenAstexViewer
3FDM A 90 - 188 Jmol OpenAstexViewer
B 90 - 188 Jmol OpenAstexViewer
C 90 - 188 Jmol OpenAstexViewer
3INQ A 90 - 188 Jmol OpenAstexViewer
B 90 - 188 Jmol OpenAstexViewer
3IO8 A 90 - 188 Jmol OpenAstexViewer
C 90 - 188 Jmol OpenAstexViewer
3PL7 A 90 - 188 Jmol OpenAstexViewer
B 90 - 188 Jmol OpenAstexViewer
3QKD A 90 - 188 Jmol OpenAstexViewer
B 90 - 188 Jmol OpenAstexViewer
3R85 A 90 - 188 Jmol OpenAstexViewer
B 90 - 188 Jmol OpenAstexViewer
C 90 - 188 Jmol OpenAstexViewer
D 90 - 188 Jmol OpenAstexViewer
3SP7 A 90 - 188 Jmol OpenAstexViewer
3SPF A 90 - 188 Jmol OpenAstexViewer
3WIZ A 90 - 188 Jmol OpenAstexViewer
B 90 - 188 Jmol OpenAstexViewer
3ZK6 A 90 - 188 Jmol OpenAstexViewer
B 90 - 188 Jmol OpenAstexViewer
3ZLN A 90 - 188 Jmol OpenAstexViewer
3ZLO A 90 - 188 Jmol OpenAstexViewer
3ZLR A 90 - 188 Jmol OpenAstexViewer
B 90 - 188 Jmol OpenAstexViewer
4A1U A 90 - 188 Jmol OpenAstexViewer
4A1W A 90 - 188 Jmol OpenAstexViewer
B 90 - 188 Jmol OpenAstexViewer
C 90 - 188 Jmol OpenAstexViewer
D 90 - 188 Jmol OpenAstexViewer
4BPK A 90 - 188 Jmol OpenAstexViewer
B 90 - 188 Jmol OpenAstexViewer
4C52 A 90 - 188 Jmol OpenAstexViewer
B 90 - 188 Jmol OpenAstexViewer
4C5D A 90 - 188 Jmol OpenAstexViewer
B 90 - 188 Jmol OpenAstexViewer
4CIN A 90 - 188 Jmol OpenAstexViewer
B 90 - 188 Jmol OpenAstexViewer
4EHR A 90 - 188 Jmol OpenAstexViewer
4HNJ A 90 - 188 Jmol OpenAstexViewer
B 90 - 188 Jmol OpenAstexViewer
4PPI A 90 - 188 Jmol OpenAstexViewer
4QVE A 90 - 188 Jmol OpenAstexViewer
4QVF A 90 - 188 Jmol OpenAstexViewer
4QVX A 90 - 188 Jmol OpenAstexViewer
B 90 - 188 Jmol OpenAstexViewer
4TUH A 90 - 188 Jmol OpenAstexViewer
B 90 - 188 Jmol OpenAstexViewer
C 90 - 188 Jmol OpenAstexViewer
D 90 - 188 Jmol OpenAstexViewer
E 90 - 188 Jmol OpenAstexViewer
F 90 - 188 Jmol OpenAstexViewer
G 90 - 188 Jmol OpenAstexViewer
H 90 - 188 Jmol OpenAstexViewer
4Z9V A 90 - 188 Jmol OpenAstexViewer
B 90 - 188 Jmol OpenAstexViewer
5B1Z A 34 - 132 Jmol OpenAstexViewer
B 34 - 132 Jmol OpenAstexViewer
5FMJ A 90 - 188 Jmol OpenAstexViewer
5FMK A 90 - 188 Jmol OpenAstexViewer
5VB1 B 90 - 188 Jmol OpenAstexViewer
D 90 - 188 Jmol OpenAstexViewer
5VB4 A 90 - 188 Jmol OpenAstexViewer
C 90 - 188 Jmol OpenAstexViewer
5VX3 A 90 - 188 Jmol OpenAstexViewer
C 90 - 188 Jmol OpenAstexViewer
E 90 - 188 Jmol OpenAstexViewer
G 90 - 188 Jmol OpenAstexViewer
6BF2 A 93 - 191 Jmol OpenAstexViewer
90 - 91 4AQ3 A 56 - 57 Jmol OpenAstexViewer
B 56 - 57 Jmol OpenAstexViewer
C 56 - 57 Jmol OpenAstexViewer
D 56 - 57 Jmol OpenAstexViewer
E 56 - 57 Jmol OpenAstexViewer
F 56 - 57 Jmol OpenAstexViewer
BH4 1 - 24 2B48 A 1 - 24 Jmol OpenAstexViewer
4HNJ A 1 - 24 Jmol OpenAstexViewer
1 - 25 3SPF A 1 - 25 Jmol OpenAstexViewer
1 - 26 1BXL A 1 - 26 Jmol OpenAstexViewer
1G5J A 5 - 30 Jmol OpenAstexViewer
1LXL A 1 - 26 Jmol OpenAstexViewer
1MAZ A 1 - 26 Jmol OpenAstexViewer
1R2D A 1 - 26 Jmol OpenAstexViewer
1R2G A 1 - 26 Jmol OpenAstexViewer
1R2H A 1 - 26 Jmol OpenAstexViewer
1R2I A 1 - 26 Jmol OpenAstexViewer
1YSG A 5 - 30 Jmol OpenAstexViewer
1YSI A 5 - 30 Jmol OpenAstexViewer
1YSN A 5 - 30 Jmol OpenAstexViewer
2LP8 A 1 - 26 Jmol OpenAstexViewer
2LPC A 1 - 26 Jmol OpenAstexViewer
2M03 A 5 - 30 Jmol OpenAstexViewer
2M04 A 1 - 26 Jmol OpenAstexViewer
2ME8 A 4 - 29 Jmol OpenAstexViewer
2ME9 A 4 - 29 Jmol OpenAstexViewer
2MEJ A 4 - 29 Jmol OpenAstexViewer
2O1Y A 5 - 30 Jmol OpenAstexViewer
2PON B 57 - 82 Jmol OpenAstexViewer
2YJ1 A 1 - 26 Jmol OpenAstexViewer
C 1 - 26 Jmol OpenAstexViewer
2YQ6 A 1 - 26 Jmol OpenAstexViewer
2YQ7 A 1 - 26 Jmol OpenAstexViewer
3FDL A 1 - 26 Jmol OpenAstexViewer
3FDM A 1 - 26 Jmol OpenAstexViewer
B 1 - 26 Jmol OpenAstexViewer
3INQ B 1 - 26 Jmol OpenAstexViewer
3IO8 A 1 - 26 Jmol OpenAstexViewer
C 1 - 26 Jmol OpenAstexViewer
3SP7 A 1 - 26 Jmol OpenAstexViewer
3ZLN A 1 - 26 Jmol OpenAstexViewer
3ZLR A 1 - 26 Jmol OpenAstexViewer
4A1U A 1 - 26 Jmol OpenAstexViewer
4A1W A 1 - 26 Jmol OpenAstexViewer
B 1 - 26 Jmol OpenAstexViewer
D 1 - 26 Jmol OpenAstexViewer
4BPK A 1 - 26 Jmol OpenAstexViewer
4C52 A 1 - 26 Jmol OpenAstexViewer
B 1 - 26 Jmol OpenAstexViewer
4C5D A 1 - 26 Jmol OpenAstexViewer
B 1 - 26 Jmol OpenAstexViewer
4CIN B 1 - 26 Jmol OpenAstexViewer
4HNJ B 1 - 26 Jmol OpenAstexViewer
4TUH A 1 - 26 Jmol OpenAstexViewer
B 1 - 26 Jmol OpenAstexViewer
C 1 - 26 Jmol OpenAstexViewer
D 1 - 26 Jmol OpenAstexViewer
E 1 - 26 Jmol OpenAstexViewer
F 1 - 26 Jmol OpenAstexViewer
G 1 - 26 Jmol OpenAstexViewer
H 1 - 26 Jmol OpenAstexViewer
4Z9V A 1 - 26 Jmol OpenAstexViewer
B 1 - 26 Jmol OpenAstexViewer
5B1Z A 1 - 26 Jmol OpenAstexViewer
B 1 - 26 Jmol OpenAstexViewer
5FMJ A 1 - 26 Jmol OpenAstexViewer
5VB1 B 1 - 26 Jmol OpenAstexViewer
D 1 - 26 Jmol OpenAstexViewer
5VB4 A 1 - 26 Jmol OpenAstexViewer
C 1 - 26 Jmol OpenAstexViewer
5VX3 A 1 - 26 Jmol OpenAstexViewer
C 1 - 26 Jmol OpenAstexViewer
E 1 - 26 Jmol OpenAstexViewer
G 1 - 26 Jmol OpenAstexViewer
6BF2 A 4 - 29 Jmol OpenAstexViewer
2 - 22 4QVX A 2 - 22 Jmol OpenAstexViewer
B 2 - 22 Jmol OpenAstexViewer
2 - 23 2O2M A 6 - 27 Jmol OpenAstexViewer
2O2N A 6 - 27 Jmol OpenAstexViewer
2 - 26 1R2E A 2 - 26 Jmol OpenAstexViewer
2P1L A 2 - 26 Jmol OpenAstexViewer
C 2 - 26 Jmol OpenAstexViewer
E 2 - 26 Jmol OpenAstexViewer
G 2 - 26 Jmol OpenAstexViewer
2YXJ B 2 - 26 Jmol OpenAstexViewer
3CVA X 2 - 26 Jmol OpenAstexViewer
3FDM C 2 - 26 Jmol OpenAstexViewer
3QKD B 2 - 26 Jmol OpenAstexViewer
3ZK6 A 2 - 26 Jmol OpenAstexViewer
B 2 - 26 Jmol OpenAstexViewer
3ZLO A 2 - 26 Jmol OpenAstexViewer
4BPK B 2 - 26 Jmol OpenAstexViewer
4CIN A 2 - 26 Jmol OpenAstexViewer
4EHR A 2 - 26 Jmol OpenAstexViewer
4QVF A 2 - 26 Jmol OpenAstexViewer
5FMK A 58 - 82 Jmol OpenAstexViewer
3 - 25 4PPI A 3 - 25 Jmol OpenAstexViewer
3 - 26 3INQ A 3 - 26 Jmol OpenAstexViewer
3PL7 A 3 - 26 Jmol OpenAstexViewer
3R85 C 3 - 26 Jmol OpenAstexViewer
D 3 - 26 Jmol OpenAstexViewer
3WIZ A 3 - 26 Jmol OpenAstexViewer
B 3 - 26 Jmol OpenAstexViewer
4A1W C 3 - 26 Jmol OpenAstexViewer
4 - 25 2YXJ A 4 - 25 Jmol OpenAstexViewer
4QVE A 4 - 25 Jmol OpenAstexViewer
4 - 26 3PL7 B 4 - 26 Jmol OpenAstexViewer
3QKD A 4 - 26 Jmol OpenAstexViewer
3R85 A 4 - 26 Jmol OpenAstexViewer
B 4 - 26 Jmol OpenAstexViewer
3ZLR B 4 - 26 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.