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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CFTR_COLGU (Q07DY5)

Summary

This is the summary of UniProt entry CFTR_COLGU (Q07DY5).

Description: Cystic fibrosis transmembrane conductance regulator EC=3.6.3.49
Source organism: Colobus guereza (Mantled guereza) (Eastern black-and-white colobus monkey) (NCBI taxonomy ID )
Length: 1481 amino acids
Reference Proteome: x

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam ABC_membrane 81 350
Pfam ABC_tran 441 576
Pfam CFTR_R 639 849
Pfam ABC_membrane 862 1147
Pfam ABC_tran 1228 1375

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q07DY5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MQRSPLEKAS VVSKLFFSWT RPILRKGYRQ RLESSDIYQI PSADSADYLS
50
51
EKLEREWDRE LASKKNPKLI NALRRCFFWR FMFYGILLYL GEVTKAVQPL
100
101
LLGRIIASYD PDNKEERSIA IYLGIGLCLL FIVRTLLLHP AIFGLHHIGM
150
151
QMRIAMFSLI YKKTLKLSSR VLDKISIGQL VSFLSNNLNK FDEGLALAHF
200
201
VWIVPLQVAL LMGLIWELLQ ASAFCGLGFL IVLALFQAGL GRMMMKYRDQ
250
251
RAGKINERLV ITSEMIENIQ SVKAYCWEEA MEKMIENLRQ TELKLTRKAA
300
301
YVRYFNSSAF FFSGFFVVFL SVLPYALIKG IVLRKIFTTI SFCIVLRMAV
350
351
TRQFPWAVQT WYDSLGAINK IQDFLQKQEY KTLEYNLTTT EVVMENVTAF
400
401
WEEGFGELFE KAKQNNSNRK TSNGDDSLFF SNFSLLGTPV LKDINFKIER
450
451
GQLLAVAGST GAGKTSLLMM IMGELEPSEG KIKHSGRISF CSQFSWIMPG
500
501
TIKENIIFGV SYDECRYRSV IKACQLEEDI SKFAEKDNIV LGEGGITLSG
550
551
GQRARISLAR AVYKDADLYL LDSPFGYLDV LTEKEIFESC VCKLMANKTR
600
601
ILVTSKMEHL KKADKILILH EGSIYFYGTF SELQNLRPDF SSKLMGYDSF
650
651
DQFSAERRNS ILTETLRRFS LEGDAPISRT ETKKQSFKQT GEFGEKRKNS
700
701
ILNPINSIRK FSIVQKTPLQ MNGIEEDSDE PLERRLSLVP DSEQGEVILP
750
751
RISVISTGPT LQARRRQSVL NLMTQSVNQG QSIHRKTAAS TRKVSLAPQA
800
801
NLTELDIYSR RLSQETGLEI SEEINEEDLK ECFFDDMESI PAVTTWNTYL
850
851
RYITVHKSLI FVLIWCLVIF LAEVAASLVV LWFLGNTPPQ DKGNSTYSRN
900
901
NSYAVIITRT SSYYVFYIYV GVADTLLAMG FFRGLPLVHT LITVSKILHH
950
951
KMLHSVLQAP MSTLNTLKAG GILNRFSKDI AILDDLLPLT IFDFIQLLLI
1000
1001
VIGAIAVVAV LQPYIFVATV PVIVAFIMLR AYFLQTSQQL KQLESEGRSP
1050
1051
IFTHLVTSLK GLWTLRAFGR QPYFETLFHK ALNLHTANWF LYLSTLRWFQ
1100
1101
MRIEMIFVIF FIAVTFISIL TTGEGEGTVG IILTLAMNIM STLQWAVNSS
1150
1151
IDVDSLMRSV SRVFKFIDMP TEEGKPTRST KPYKNGQLLK VMIIENSHVK
1200
1201
KDDIWPSGGQ MTIKDLTAKY TEGGNPILEN ISFSISPGQR VGLLGRTGSG
1250
1251
KSTLLSAFLR LLNTKGEIQI DGVSWDSVTL QQWRKAFGVI PQKVFIFSGT
1300
1301
FRKNLDPYEQ WSDQEIWKVA DEVGLRSVIE QFPGKLDFVL VDGGCVLSHG
1350
1351
HKQLMCLARS VLSKAKILLL DEPSAHLDPV TYQIIRRTLK QAFADCTVIL
1400
1401
CEHRIEAMLE CQQFLVIEEN KVRQYDSIQK LLNERSLFRQ AISPSDRVKL
1450
1451
FPHRNSSKCK SQPQIAALKE ETEEEVQDTR L                    
1481
 

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Checksums:
CRC64:25243A75C10F5DE5
MD5:56c98bb666ecd39806808a57d0844852