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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: KCNA1_HUMAN (Q09470)

Summary

This is the summary of UniProt entry KCNA1_HUMAN (Q09470).

Description: Potassium voltage-gated channel subfamily A member 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 495 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 5 29
Pfam BTB_2 39 130
Pfam Ion_trans 166 419
low_complexity n/a 167 182
transmembrane n/a 168 189
transmembrane n/a 221 242
transmembrane n/a 249 267
transmembrane n/a 287 305
low_complexity n/a 289 302
low_complexity n/a 325 339
transmembrane n/a 326 347
low_complexity n/a 346 352
transmembrane n/a 387 408
low_complexity n/a 436 451
disorder n/a 441 442
disorder n/a 448 449
disorder n/a 452 453

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q09470. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTVMSGENVD EASAAPGHPQ DGSYPRQADH DDHECCERVV INISGLRFET
50
51
QLKTLAQFPN TLLGNPKKRM RYFDPLRNEY FFDRNRPSFD AILYYYQSGG
100
101
RLRRPVNVPL DMFSEEIKFY ELGEEAMEKF REDEGFIKEE ERPLPEKEYQ
150
151
RQVWLLFEYP ESSGPARVIA IVSVMVILIS IVIFCLETLP ELKDDKDFTG
200
201
TVHRIDNTTV IYNSNIFTDP FFIVETLCII WFSFELVVRF FACPSKTDFF
250
251
KNIMNFIDIV AIIPYFITLG TEIAEQEGNQ KGEQATSLAI LRVIRLVRVF
300
301
RIFKLSRHSK GLQILGQTLK ASMRELGLLI FFLFIGVILF SSAVYFAEAE
350
351
EAESHFSSIP DAFWWAVVSM TTVGYGDMYP VTIGGKIVGS LCAIAGVLTI
400
401
ALPVPVIVSN FNYFYHRETE GEEQAQLLHV SSPNLASDSD LSRRSSSTMS
450
451
KSEYMEIEED MNNSIAHYRQ VNIRTANCTT ANQNCVNKSK LLTDV     
495
 

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Checksums:
CRC64:0A1B1AB87BCDDEBA
MD5:9b6ab03d8d060da88ee72452614cca2b

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.