Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MGAT2_HUMAN (Q10469)

Summary

This is the summary of UniProt entry MGAT2_HUMAN (Q10469).

Description: Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase EC=2.4.1.143
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 447 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
sig_p n/a 1 29
low_complexity n/a 34 46
disorder n/a 36 41
low_complexity n/a 46 54
disorder n/a 47 50
Pfam MGAT2 92 440

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q10469. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MRFRIYKRKV LILTLVVAAC GFVLWSSNGR QRKNEALAPP LLDAEPARGA
50
51
GGRGGDHPSV AVGIRRVSNV SAASLVPAVP QPEADNLTLR YRSLVYQLNF
100
101
DQTLRNVDKA GTWAPRELVL VVQVHNRPEY LRLLLDSLRK AQGIDNVLVI
150
151
FSHDFWSTEI NQLIAGVNFC PVLQVFFPFS IQLYPNEFPG SDPRDCPRDL
200
201
PKNAALKLGC INAEYPDSFG HYREAKFSQT KHHWWWKLHF VWERVKILRD
250
251
YAGLILFLEE DHYLAPDFYH VFKKMWKLKQ QECPECDVLS LGTYSASRSF
300
301
YGMADKVDVK TWKSTEHNMG LALTRNAYQK LIECTDTFCT YDDYNWDWTL
350
351
QYLTVSCLPK FWKVLVPQIP RIFHAGDCGM HHKKTCRPST QSAQIESLLN
400
401
NNKQYMFPET LTISEKFTVV AISPPRKNGG WGDIRDHELC KSYRRLQ   
447
 

Show the unformatted sequence.

Checksums:
CRC64:533B76D08BD8A572
MD5:21fd6022e62470b9dd6d11132a5e5895

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
MGAT2 92 - 440 5VCM A 92 - 440 Jmol OpenAstexViewer
B 92 - 440 Jmol OpenAstexViewer
5VCR A 92 - 440 Jmol OpenAstexViewer
B 92 - 440 Jmol OpenAstexViewer
5VCS A 92 - 440 Jmol OpenAstexViewer
B 92 - 440 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.