Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: NTCP2_HUMAN (Q12908)

Summary

This is the summary of UniProt entry NTCP2_HUMAN (Q12908).

Description: Ileal sodium/bile acid cotransporter
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 348 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
low_complexity n/a 28 44
transmembrane n/a 29 53
Pfam SBF 39 220
transmembrane n/a 65 89
transmembrane n/a 95 119
transmembrane n/a 131 153
low_complexity n/a 134 145
transmembrane n/a 165 184
transmembrane n/a 196 220
low_complexity n/a 198 214
transmembrane n/a 226 245
transmembrane n/a 257 278
transmembrane n/a 290 311
disorder n/a 321 327
disorder n/a 336 337

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q12908. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MNDPNSCVDN ATVCSGASCV VPESNFNNIL SVVLSTVLTI LLALVMFSMG
50
51
CNVEIKKFLG HIKRPWGICV GFLCQFGIMP LTGFILSVAF DILPLQAVVV
100
101
LIIGCCPGGT ASNILAYWVD GDMDLSVSMT TCSTLLALGM MPLCLLIYTK
150
151
MWVDSGSIVI PYDNIGTSLV SLVVPVSIGM FVNHKWPQKA KIILKIGSIA
200
201
GAILIVLIAV VGGILYQSAW IIAPKLWIIG TIFPVAGYSL GFLLARIAGL
250
251
PWYRCRTVAF ETGMQNTQLC STIVQLSFTP EELNVVFTFP LIYSIFQLAF
300
301
AAIFLGFYVA YKKCHGKNKA EIPESKENGT EPESSFYKAN GGFQPDEK  
348
 

Show the unformatted sequence.

Checksums:
CRC64:9794EAA77C3EC4F9
MD5:7dfb0baf8b2c3fe999535b3817b04e6b

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.