Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: FOXF1_HUMAN (Q12946)

Summary

This is the summary of UniProt entry FOXF1_HUMAN (Q12946).

Description: Forkhead box protein F1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 379 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
disorder n/a 1 44
low_complexity n/a 12 22
Pfam Forkhead 47 133
low_complexity n/a 107 118
low_complexity n/a 136 145
disorder n/a 203 216
disorder n/a 219 220
disorder n/a 235 237
disorder n/a 239 251
low_complexity n/a 263 276
disorder n/a 295 302
disorder n/a 304 332
low_complexity n/a 349 365

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q12946. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSSAPEKQQP PHGGGGGGGG GGGAAMDPAS SGPSKAKKTN AGIRRPEKPP
50
51
YSYIALIVMA IQSSPTKRLT LSEIYQFLQS RFPFFRGSYQ GWKNSVRHNL
100
101
SLNECFIKLP KGLGRPGKGH YWTIDPASEF MFEEGSFRRR PRGFRRKCQA
150
151
LKPMYSMMNG LGFNHLPDTY GFQGSAGGLS CPPNSLALEG GLGMMNGHLP
200
201
GNVDGMALPS HSVPHLPSNG GHSYMGGCGG AAAGEYPHHD SSVPASPLLP
250
251
TGAGGVMEPH AVYSGSAAAW PPSASAALNS GASYIKQQPL SPCNPAANPL
300
301
SGSLSTHSLE QPYLHQNSHN APAELQGIPR YHSQSPSMCD RKEFVFSFNA
350
351
MASSSMHSAG GGSYYHQQVT YQDIKPCVM                       
379
 

Show the unformatted sequence.

Checksums:
CRC64:CA3DE3CEFB94FC3E
MD5:e7927d7e0a3823aec2c171239c8a879d

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.