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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PP1R8_HUMAN (Q12972)

Summary

This is the summary of UniProt entry PP1R8_HUMAN (Q12972).

Description: Nuclear inhibitor of protein phosphatase 1 Activator of RNA decay EC=3.1.4.-
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 351 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
low_complexity n/a 34 48
Pfam FHA 49 118
disorder n/a 110 113
disorder n/a 128 144
low_complexity n/a 143 163
disorder n/a 146 157
disorder n/a 161 170
disorder n/a 174 175
disorder n/a 180 224
disorder n/a 230 252
low_complexity n/a 238 250
disorder n/a 257 289
disorder n/a 298 299
disorder n/a 303 310
disorder n/a 312 340
disorder n/a 346 348

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q12972. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAAAANSGSS LPLFDCPTWA GKPPPGLHLD VVKGDKLIEK LIIDEKKYYL
50
51
FGRNPDLCDF TIDHQSCSRV HAALVYHKHL KRVFLIDLNS THGTFLGHIR
100
101
LEPHKPQQIP IDSTVSFGAS TRAYTLREKP QTLPSAVKGD EKMGGEDDEL
150
151
KGLLGLPEEE TELDNLTEFN TAHNKRISTL TIEEGNLDIQ RPKRKRKNSR
200
201
VTFSEDDEII NPEDVDPSVG RFRNMVQTAV VPVKKKRVEG PGSLGLEESG
250
251
SRRMQNFAFS GGLYGGLPPT HSEAGSQPHG IHGTALIGGL PMPYPNLAPD
300
301
VDLTPVVPSA VNMNPAPNPA VYNPEAVNEP KKKKYAKEAW PGKKPTPSLL
350
351
I                                                     
351
 

Show the unformatted sequence.

Checksums:
CRC64:0A0E92B033E37641
MD5:f53f4f38a7cb4fc494c21d4c59a35528

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.