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14  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ZBT17_HUMAN (Q13105)

Summary

This is the summary of UniProt entry ZBT17_HUMAN (Q13105).

Description: Zinc finger and BTB domain-containing protein 17
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 803 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam BTB 14 113
disorder n/a 115 116
disorder n/a 119 296
low_complexity n/a 170 180
low_complexity n/a 206 223
low_complexity n/a 229 244
low_complexity n/a 258 270
Pfam zf-C2H2 306 328
disorder n/a 322 324
Pfam zf-C2H2 390 412
Pfam zf-C2H2 418 440
disorder n/a 434 436
disorder n/a 438 439
Pfam zf-C2H2 446 468
Pfam zf-C2H2 474 496
Pfam zf-C2H2 530 552
Pfam zf-C2H2 558 580
disorder n/a 575 576
Pfam zf-C2H2 586 608
Pfam zf-C2H2 614 637
low_complexity n/a 663 683
coiled_coil n/a 689 709
disorder n/a 700 703
disorder n/a 774 776
disorder n/a 779 803

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q13105. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDFPQHSQHV LEQLNQQRQL GLLCDCTFVV DGVHFKAHKA VLAACSEYFK
50
51
MLFVDQKDVV HLDISNAAGL GQVLEFMYTA KLSLSPENVD DVLAVATFLQ
100
101
MQDIITACHA LKSLAEPATS PGGNAEALAT EGGDKRAKEE KVATSTLSRL
150
151
EQAGRSTPIG PSRDLKEERG GQAQSAASGA EQTEKADAPR EPPPVELKPD
200
201
PTSGMAAAEA EAALSESSEQ EMEVEPARKG EEEQKEQEEQ EEEGAGPAEV
250
251
KEEGSQLENG EAPEENENEE SAGTDSGQEL GSEARGLRSG TYGDRTESKA
300
301
YGSVIHKCED CGKEFTHTGN FKRHIRIHTG EKPFSCRECS KAFSDPAACK
350
351
AHEKTHSPLK PYGCEECGKS YRLISLLNLH KKRHSGEARY RCEDCGKLFT
400
401
TSGNLKRHQL VHSGEKPYQC DYCGRSFSDP TSKMRHLETH DTDKEHKCPH
450
451
CDKKFNQVGN LKAHLKIHIA DGPLKCRECG KQFTTSGNLK RHLRIHSGEK
500
501
PYVCIHCQRQ FADPGALQRH VRIHTGEKPC QCVMCGKAFT QASSLIAHVR
550
551
QHTGEKPYVC ERCGKRFVQS SQLANHIRHH DNIRPHKCSV CSKAFVNVGD
600
601
LSKHIIIHTG EKPYLCDKCG RGFNRVDNLR SHVKTVHQGK AGIKILEPEE
650
651
GSEVSVVTVD DMVTLATEAL AATAVTQLTV VPVGAAVTAD ETEVLKAEIS
700
701
KAVKQVQEED PNTHILYACD SCGDKFLDAN SLAQHVRIHT AQALVMFQTD
750
751
ADFYQQYGPG GTWPAGQVLQ AGELVFRPRD GAEGQPALAE TSPTAPECPP
800
801
PAE                                                   
803
 

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Checksums:
CRC64:C159D177C8A2D4A3
MD5:b89bceea6b21bcfac3d0f343d550d4d2

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
BTB 14 - 111 7AZX B 14 - 111 Show 3D Structure View in InterPro
14 - 113 2Q81 A 14 - 113 Show 3D Structure View in InterPro
B 14 - 113 Show 3D Structure View in InterPro
C 14 - 113 Show 3D Structure View in InterPro
D 14 - 113 Show 3D Structure View in InterPro
3M52 A 14 - 113 Show 3D Structure View in InterPro
B 14 - 113 Show 3D Structure View in InterPro
4U2M A 14 - 113 Show 3D Structure View in InterPro
B 14 - 113 Show 3D Structure View in InterPro
C 14 - 113 Show 3D Structure View in InterPro
D 14 - 113 Show 3D Structure View in InterPro
4U2N A 14 - 113 Show 3D Structure View in InterPro
B 14 - 113 Show 3D Structure View in InterPro
7AZX A 14 - 113 Show 3D Structure View in InterPro
zf-C2H2 390 - 412 2N26 A 88 - 110 Show 3D Structure View in InterPro
418 - 440 2M0D A 4 - 26 Show 3D Structure View in InterPro
446 - 468 2M0E A 32 - 54 Show 3D Structure View in InterPro
474 - 496 2M0F A 60 - 82 Show 3D Structure View in InterPro
530 - 552 2LVT A 32 - 54 Show 3D Structure View in InterPro
558 - 580 2LVU A 60 - 82 Show 3D Structure View in InterPro
7MC1 A 4 - 26 Show 3D Structure View in InterPro
586 - 608 7MC2 A 32 - 54 Show 3D Structure View in InterPro
614 - 637 7MC3 A 60 - 83 Show 3D Structure View in InterPro
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The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;