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12  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PRDX4_HUMAN (Q13162)

Summary

This is the summary of UniProt entry PRDX4_HUMAN (Q13162).

Description: Peroxiredoxin-4
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 271 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
sig_p n/a 1 37
low_complexity n/a 19 30
low_complexity n/a 38 49
disorder n/a 39 41
Pfam AhpC-TSA 81 214
Pfam 1-cysPrx_C 234 267

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q13162. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEALPLLAAT TPDHGRHRRL LLLPLLLFLL PAGAVQGWET EERPRTREEE
50
51
CHFYAGGQVY PGEASRVSVA DHSLHLSKAK ISKPAPYWEG TAVIDGEFKE
100
101
LKLTDYRGKY LVFFFYPLDF TFVCPTEIIA FGDRLEEFRS INTEVVACSV
150
151
DSQFTHLAWI NTPRRQGGLG PIRIPLLSDL THQISKDYGV YLEDSGHTLR
200
201
GLFIIDDKGI LRQITLNDLP VGRSVDETLR LVQAFQYTDK HGEVCPAGWK
250
251
PGSETIIPDP AGKLKYFDKL N                               
271
 

Show the unformatted sequence.

Checksums:
CRC64:7E56B580049FC60F
MD5:22c516256a06e9363d57f28f9da25fcd

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
1-cysPrx_C 234 - 241 3TKQ C 197 - 204 Jmol OpenAstexViewer
D 197 - 204 Jmol OpenAstexViewer
E 197 - 204 Jmol OpenAstexViewer
234 - 242 3TJB B 234 - 242 Jmol OpenAstexViewer
C 234 - 242 Jmol OpenAstexViewer
E 234 - 242 Jmol OpenAstexViewer
3TJG E 234 - 242 Jmol OpenAstexViewer
3TJJ A 234 - 242 Jmol OpenAstexViewer
B 234 - 242 Jmol OpenAstexViewer
C 234 - 242 Jmol OpenAstexViewer
D 234 - 242 Jmol OpenAstexViewer
E 234 - 242 Jmol OpenAstexViewer
4RQX A 234 - 242 Jmol OpenAstexViewer
B 234 - 242 Jmol OpenAstexViewer
C 234 - 242 Jmol OpenAstexViewer
D 234 - 242 Jmol OpenAstexViewer
E 234 - 242 Jmol OpenAstexViewer
234 - 243 3TJG A 234 - 243 Jmol OpenAstexViewer
234 - 245 3TJB A 234 - 245 Jmol OpenAstexViewer
D 234 - 245 Jmol OpenAstexViewer
3TJG D 234 - 245 Jmol OpenAstexViewer
234 - 246 3TJG B 234 - 246 Jmol OpenAstexViewer
C 234 - 246 Jmol OpenAstexViewer
234 - 250 5HQP B 234 - 250 Jmol OpenAstexViewer
234 - 256 5HQP A 234 - 256 Jmol OpenAstexViewer
234 - 260 3TKQ B 197 - 223 Jmol OpenAstexViewer
234 - 267 2PN8 A 234 - 267 Jmol OpenAstexViewer
B 234 - 267 Jmol OpenAstexViewer
C 234 - 267 Jmol OpenAstexViewer
D 234 - 267 Jmol OpenAstexViewer
E 234 - 267 Jmol OpenAstexViewer
F 234 - 267 Jmol OpenAstexViewer
G 234 - 267 Jmol OpenAstexViewer
H 234 - 267 Jmol OpenAstexViewer
I 234 - 267 Jmol OpenAstexViewer
J 234 - 267 Jmol OpenAstexViewer
3TJF A 234 - 267 Jmol OpenAstexViewer
B 234 - 267 Jmol OpenAstexViewer
C 234 - 267 Jmol OpenAstexViewer
D 234 - 267 Jmol OpenAstexViewer
E 234 - 267 Jmol OpenAstexViewer
3TJK A 234 - 267 Jmol OpenAstexViewer
B 234 - 267 Jmol OpenAstexViewer
C 234 - 267 Jmol OpenAstexViewer
D 234 - 267 Jmol OpenAstexViewer
E 234 - 267 Jmol OpenAstexViewer
3TKP A 197 - 230 Jmol OpenAstexViewer
B 197 - 230 Jmol OpenAstexViewer
C 197 - 230 Jmol OpenAstexViewer
D 197 - 230 Jmol OpenAstexViewer
E 197 - 230 Jmol OpenAstexViewer
3TKQ A 197 - 230 Jmol OpenAstexViewer
3TKR A 197 - 230 Jmol OpenAstexViewer
B 197 - 230 Jmol OpenAstexViewer
C 197 - 230 Jmol OpenAstexViewer
D 197 - 230 Jmol OpenAstexViewer
E 197 - 230 Jmol OpenAstexViewer
F 197 - 230 Jmol OpenAstexViewer
G 197 - 230 Jmol OpenAstexViewer
H 197 - 230 Jmol OpenAstexViewer
I 197 - 230 Jmol OpenAstexViewer
J 197 - 230 Jmol OpenAstexViewer
3TKS A 197 - 230 Jmol OpenAstexViewer
B 197 - 230 Jmol OpenAstexViewer
C 197 - 230 Jmol OpenAstexViewer
D 197 - 230 Jmol OpenAstexViewer
E 197 - 230 Jmol OpenAstexViewer
AhpC-TSA 81 - 214 3TJB A 81 - 214 Jmol OpenAstexViewer
B 81 - 214 Jmol OpenAstexViewer
C 81 - 214 Jmol OpenAstexViewer
D 81 - 214 Jmol OpenAstexViewer
E 81 - 214 Jmol OpenAstexViewer
3TJF A 81 - 214 Jmol OpenAstexViewer
B 81 - 214 Jmol OpenAstexViewer
C 81 - 214 Jmol OpenAstexViewer
D 81 - 214 Jmol OpenAstexViewer
E 81 - 214 Jmol OpenAstexViewer
3TJG A 81 - 214 Jmol OpenAstexViewer
B 81 - 214 Jmol OpenAstexViewer
C 81 - 214 Jmol OpenAstexViewer
D 81 - 214 Jmol OpenAstexViewer
E 81 - 214 Jmol OpenAstexViewer
3TJJ A 81 - 214 Jmol OpenAstexViewer
B 81 - 214 Jmol OpenAstexViewer
C 81 - 214 Jmol OpenAstexViewer
D 81 - 214 Jmol OpenAstexViewer
E 81 - 214 Jmol OpenAstexViewer
3TJK A 81 - 214 Jmol OpenAstexViewer
B 81 - 214 Jmol OpenAstexViewer
C 81 - 214 Jmol OpenAstexViewer
D 81 - 214 Jmol OpenAstexViewer
E 81 - 214 Jmol OpenAstexViewer
3TKP A 44 - 177 Jmol OpenAstexViewer
B 44 - 177 Jmol OpenAstexViewer
C 44 - 177 Jmol OpenAstexViewer
D 44 - 177 Jmol OpenAstexViewer
E 44 - 177 Jmol OpenAstexViewer
3TKQ A 44 - 177 Jmol OpenAstexViewer
B 44 - 177 Jmol OpenAstexViewer
C 44 - 177 Jmol OpenAstexViewer
D 44 - 177 Jmol OpenAstexViewer
E 44 - 177 Jmol OpenAstexViewer
3TKR A 44 - 177 Jmol OpenAstexViewer
B 44 - 177 Jmol OpenAstexViewer
C 44 - 177 Jmol OpenAstexViewer
D 44 - 177 Jmol OpenAstexViewer
E 44 - 177 Jmol OpenAstexViewer
F 44 - 177 Jmol OpenAstexViewer
G 44 - 177 Jmol OpenAstexViewer
H 44 - 177 Jmol OpenAstexViewer
I 44 - 177 Jmol OpenAstexViewer
J 44 - 177 Jmol OpenAstexViewer
3TKS A 44 - 177 Jmol OpenAstexViewer
B 44 - 177 Jmol OpenAstexViewer
C 44 - 177 Jmol OpenAstexViewer
D 44 - 177 Jmol OpenAstexViewer
E 44 - 177 Jmol OpenAstexViewer
4RQX A 81 - 214 Jmol OpenAstexViewer
B 81 - 214 Jmol OpenAstexViewer
C 81 - 214 Jmol OpenAstexViewer
D 81 - 214 Jmol OpenAstexViewer
E 81 - 214 Jmol OpenAstexViewer
5HQP A 81 - 214 Jmol OpenAstexViewer
B 81 - 214 Jmol OpenAstexViewer
84 - 214 2PN8 A 84 - 214 Jmol OpenAstexViewer
B 84 - 214 Jmol OpenAstexViewer
C 84 - 214 Jmol OpenAstexViewer
D 84 - 214 Jmol OpenAstexViewer
E 84 - 214 Jmol OpenAstexViewer
F 84 - 214 Jmol OpenAstexViewer
G 84 - 214 Jmol OpenAstexViewer
H 84 - 214 Jmol OpenAstexViewer
I 84 - 214 Jmol OpenAstexViewer
J 84 - 214 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.