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5  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: BIRC3_HUMAN (Q13489)

Summary

This is the summary of UniProt entry BIRC3_HUMAN (Q13489).

Description: Baculoviral IAP repeat-containing protein 3
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 604 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam BIR 32 97
disorder n/a 110 112
disorder n/a 118 121
low_complexity n/a 136 147
disorder n/a 149 150
Pfam BIR 172 236
Pfam BIR 258 323
disorder n/a 356 364
low_complexity n/a 411 421
coiled_coil n/a 413 440
low_complexity n/a 423 439
disorder n/a 427 436
disorder n/a 438 441
Pfam CARD 444 528
low_complexity n/a 544 554
Pfam zf-C3HC4_3 553 598

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q13489. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MNIVENSIFL SNLMKSANTF ELKYDLSCEL YRMSTYSTFP AGVPVSERSL
50
51
ARAGFYYTGV NDKVKCFCCG LMLDNWKRGD SPTEKHKKLY PSCRFVQSLN
100
101
SVNNLEATSQ PTFPSSVTNS THSLLPGTEN SGYFRGSYSN SPSNPVNSRA
150
151
NQDFSALMRS SYHCAMNNEN ARLLTFQTWP LTFLSPTDLA KAGFYYIGPG
200
201
DRVACFACGG KLSNWEPKDN AMSEHLRHFP KCPFIENQLQ DTSRYTVSNL
250
251
SMQTHAARFK TFFNWPSSVL VNPEQLASAG FYYVGNSDDV KCFCCDGGLR
300
301
CWESGDDPWV QHAKWFPRCE YLIRIKGQEF IRQVQASYPH LLEQLLSTSD
350
351
SPGDENAESS IIHFEPGEDH SEDAIMMNTP VINAAVEMGF SRSLVKQTVQ
400
401
RKILATGENY RLVNDLVLDL LNAEDEIREE ERERATEEKE SNDLLLIRKN
450
451
RMALFQHLTC VIPILDSLLT AGIINEQEHD VIKQKTQTSL QARELIDTIL
500
501
VKGNIAATVF RNSLQEAEAV LYEHLFVQQD IKYIPTEDVS DLPVEEQLRR
550
551
LQEERTCKVC MDKEVSIVFI PCGHLVVCKD CAPSLRKCPI CRSTIKGTVR
600
601
TFLS                                                  
604
 

Show the unformatted sequence.

Checksums:
CRC64:8581A00BA9AAB4A7
MD5:7863b835314a8b12e514f52ef1e4665a

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
BIR 258 - 323 2UVL A 258 - 323 Jmol OpenAstexViewer
B 258 - 323 Jmol OpenAstexViewer
32 - 97 3M0A D 32 - 97 Jmol OpenAstexViewer
3M0D D 32 - 97 Jmol OpenAstexViewer
zf-C3HC4_3 553 - 598 3EB5 A 553 - 598 Jmol OpenAstexViewer
3EB6 A 553 - 598 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.