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9  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ULA1_HUMAN (Q13564)

Summary

This is the summary of UniProt entry ULA1_HUMAN (Q13564).

Description: NEDD8-activating enzyme E1 regulatory subunit
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 534 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam ThiF 13 533
disorder n/a 255 269
disorder n/a 271 272
disorder n/a 326 327

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q13564. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAQLGKLLKE QKYDRQLRLW GDHGQEALES AHVCLINATA TGTEILKNLV
50
51
LPGIGSFTII DGNQVSGEDA GNNFFLQRSS IGKNRAEAAM EFLQELNSDV
100
101
SGSFVEESPE NLLDNDPSFF CRFTVVVATQ LPESTSLRLA DVLWNSQIPL
150
151
LICRTYGLVG YMRIIIKEHP VIESHPDNAL EDLRLDKPFP ELREHFQSYD
200
201
LDHMEKKDHS HTPWIVIIAK YLAQWYSETN GRIPKTYKEK EDFRDLIRQG
250
251
ILKNENGAPE DEENFEEAIK NVNTALNTTQ IPSSIEDIFN DDRCINITKQ
300
301
TPSFWILARA LKEFVAKEGQ GNLPVRGTIP DMIADSGKYI KLQNVYREKA
350
351
KKDAAAVGNH VAKLLQSIGQ APESISEKEL KLLCSNSAFL RVVRCRSLAE
400
401
EYGLDTINKD EIISSMDNPD NEIVLYLMLR AVDRFHKQQG RYPGVSNYQV
450
451
EEDIGKLKSC LTGFLQEYGL SVMVKDDYVH EFCRYGAAEP HTIAAFLGGA
500
501
AAQEVIKIIT KQFVIFNNTY IYSGMSQTSA TFQL                 
534
 

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Checksums:
CRC64:5EC8D3ACE6374F21
MD5:bcdbf5272256bd08237ecd4a83de9657

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
ThiF 13 - 533 1R4M A 13 - 533 Jmol OpenAstexViewer
C 13 - 533 Jmol OpenAstexViewer
E 13 - 533 Jmol OpenAstexViewer
G 13 - 533 Jmol OpenAstexViewer
1R4N A 13 - 533 Jmol OpenAstexViewer
C 13 - 533 Jmol OpenAstexViewer
E 13 - 533 Jmol OpenAstexViewer
G 13 - 533 Jmol OpenAstexViewer
1TT5 A 13 - 533 Jmol OpenAstexViewer
C 13 - 533 Jmol OpenAstexViewer
1YOV A 13 - 533 Jmol OpenAstexViewer
C 13 - 533 Jmol OpenAstexViewer
2NVU A 13 - 533 Jmol OpenAstexViewer
3DBH A 13 - 533 Jmol OpenAstexViewer
C 13 - 533 Jmol OpenAstexViewer
E 13 - 533 Jmol OpenAstexViewer
G 13 - 533 Jmol OpenAstexViewer
3DBL A 13 - 533 Jmol OpenAstexViewer
C 13 - 533 Jmol OpenAstexViewer
E 13 - 533 Jmol OpenAstexViewer
G 13 - 533 Jmol OpenAstexViewer
3DBR A 13 - 533 Jmol OpenAstexViewer
C 13 - 533 Jmol OpenAstexViewer
E 13 - 533 Jmol OpenAstexViewer
G 13 - 533 Jmol OpenAstexViewer
3GZN A 20 - 540 Jmol OpenAstexViewer
C 20 - 540 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.