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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: GIT2_HUMAN (Q14161)

Summary

This is the summary of UniProt entry GIT2_HUMAN (Q14161).

Description: ARF GTPase-activating protein GIT2
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 759 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam ArfGap 1 120
disorder n/a 87 102
disorder n/a 133 137
Pfam Ank 166 198
disorder n/a 173 174
disorder n/a 197 208
disorder n/a 245 247
low_complexity n/a 252 273
Pfam GIT_SHD 266 294
disorder n/a 318 322
disorder n/a 324 325
disorder n/a 327 331
Pfam GIT_SHD 330 358
disorder n/a 357 362
disorder n/a 373 425
Pfam GIT_CC 414 478
disorder n/a 431 432
coiled_coil n/a 437 478
disorder n/a 444 446
disorder n/a 448 453
disorder n/a 455 456
disorder n/a 458 557
low_complexity n/a 554 569
disorder n/a 559 666
Pfam GIT1_C 636 752
coiled_coil n/a 644 664
disorder n/a 669 673
disorder n/a 683 684
disorder n/a 687 691
disorder n/a 713 726
disorder n/a 753 759

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q14161. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSKRLRSSEV CADCSGPDPS WASVNRGTFL CDECCSVHRS LGRHISQVRH
50
51
LKHTPWPPTL LQMVETLYNN GANSIWEHSL LDPASIMSGR RKANPQDKVH
100
101
PNKAEFIRAK YQMLAFVHRL PCRDDDSVTA KDLSKQLHSS VRTGNLETCL
150
151
RLLSLGAQAN FFHPEKGNTP LHVASKAGQI LQAELLAVYG ADPGTQDSSG
200
201
KTPVDYARQG GHHELAERLV EIQYELTDRL AFYLCGRKPD HKNGQHFIIP
250
251
QMADSSLDLS ELAKAAKKKL QSLSNHLFEE LAMDVYDEVD RRETDAVWLA
300
301
TQNHSALVTE TTVVPFLPVN PEYSSTRNQG RQKLARFNAH EFATLVIDIL
350
351
SDAKRRQQGS SLSGSKDNVE LILKTINNQH SVESQDNDQP DYDSVASDED
400
401
TDLETTASKT NRQKSLDSDL SDGPVTVQEF MEVKNALVAS EAKIQQLMKV
450
451
NNNLSDELRI MQKKLQTLQS ENSNLRKQAT TNVYQVQTGS EYTDTSNHSS
500
501
LKRRPSARGS RPMSMYETGS GQKPYLPMGE ASRPEESRMR LQPFPAHIGR
550
551
SALVTSSSSL PSFPSTLSWS RDESARRASR LEKQNSTPES DYDNTPNDME
600
601
PDGMGSSRKG RQRSMVWPGD GLVPDTAEPH VAPSPTLPST EDVIRKTEQI
650
651
TKNIQELLRA AQENKHDSYI PCSERIHVAV TEMAALFPKK PKSDMVRTSL
700
701
RLLTSSAYRL QSECKKTLPG DPGSPTDVQL VTQQVIQCAY DIAKAAKQLV
750
751
TITTKENNN                                             
759
 

Show the unformatted sequence.

Checksums:
CRC64:07EFE266DB2F3258
MD5:ee51bfc95eab1b8073d0a4bb7d5a9728

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.