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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: DMC1_HUMAN (Q14565)

Summary

This is the summary of UniProt entry DMC1_HUMAN (Q14565).

Description: Meiotic recombination protein DMC1/LIM15 homolog
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 340 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 5 9
Pfam Rad51 83 338
coiled_coil n/a 239 259
disorder n/a 276 281
disorder n/a 314 316
disorder n/a 326 332

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q14565. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKEDQVVAEE PGFQDEEESL FQDIDLLQKH GINVADIKKL KSVGICTIKG
50
51
IQMTTRRALC NVKGLSEAKV DKIKEAANKL IEPGFLTAFE YSEKRKMVFH
100
101
ITTGSQEFDK LLGGGIESMA ITEAFGEFRT GKTQLSHTLC VTAQLPGAGG
150
151
YPGGKIIFID TENTFRPDRL RDIADRFNVD HDAVLDNVLY ARAYTSEHQM
200
201
ELLDYVAAKF HEEAGIFKLL IIDSIMALFR VDFSGRGELA ERQQKLAQML
250
251
SRLQKISEEY NVAVFVTNQM TADPGATMTF QADPKKPIGG HILAHASTTR
300
301
ISLRKGRGEL RIAKIYDSPE MPENEATFAI TAGGIGDAKE           
340
 

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Checksums:
CRC64:040A6E4CF1FEBFA2
MD5:6c1fa76091f2786526841d444bd381a4

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Rad51 83 - 338 1V5W A 83 - 338 Jmol OpenAstexViewer
B 83 - 338 Jmol OpenAstexViewer
2ZJB A 83 - 338 Jmol OpenAstexViewer
B 83 - 338 Jmol OpenAstexViewer
84 - 338 4HYY A 84 - 338 Jmol OpenAstexViewer
B 84 - 338 Jmol OpenAstexViewer
C 84 - 338 Jmol OpenAstexViewer
D 84 - 338 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.