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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RASA3_HUMAN (Q14644)

Summary

This is the summary of UniProt entry RASA3_HUMAN (Q14644).

Description: Ras GTPase-activating protein 3
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 834 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam C2 12 114
Pfam C2 145 265
disorder n/a 181 182
disorder n/a 184 185
Pfam RasGAP 351 423
Pfam RasGAP 418 524
Pfam PH 577 677
Pfam BTK 685 714
disorder n/a 764 765
disorder n/a 800 810
disorder n/a 814 823
disorder n/a 825 826
disorder n/a 830 834

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q14644. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAVEDEGLRV FQSVKIKIGE AKNLPSYPGP SKMRDCYCTV NLDQEEVFRT
50
51
KIVEKSLCPF YGEDFYCEIP RSFRHLSFYI FDRDVFRRDS IIGKVAIQKE
100
101
DLQKYHNRDT WFQLQHVDAD SEVQGKVHLE LRLSEVITDT GVVCHKLATR
150
151
IVECQGLPIV NGQCDPYATV TLAGPFRSEA KKTKVKRKTN NPQFDEVFYF
200
201
EVTRPCSYSK KSHFDFEEED VDKLEIRVDL WNASNLKFGD EFLGELRIPL
250
251
KVLRQSSSYE AWYFLQPRDN GSKSLKPDDL GSLRLNVVYT EDHVFSSDYY
300
301
SPLRDLLLKS ADVEPVSASA AHILGEVCRE KQEAAVPLVR LFLHYGRVVP
350
351
FISAIASAEV KRTQDPNTIF RGNSLASKCI DETMKLAGMH YLHVTLKPAI
400
401
EEICQSHKPC EIDPVKLKDG ENLENNMENL RQYVDRVFHA ITESGVSCPT
450
451
VMCDIFFSLR EAAAKRFQDD PDVRYTAVSS FIFLRFFAPA ILSPNLFQLT
500
501
PHHTDPQTSR TLTLISKTVQ TLGSLSKSKS ASFKESYMAT FYEFFNEQKY
550
551
ADAVKNFLDL ISSSGRRDPK SVEQPIVLKE GFMIKRAQGR KRFGMKNFKK
600
601
RWFRLTNHEF TYHKSKGDQP LYSIPIENIL AVEKLEEESF KMKNMFQVIQ
650
651
PERALYIQAN NCVEAKDWID ILTKVSQCNQ KRLTVYHPSA YLSGHWLCCR
700
701
APSDSAPGCS PCTGGLPANI QLDIDGDRET ERIYSLFNLY MSKLEKMQEA
750
751
CGSKSVYDGP EQEEYSTFVI DDPQETYKTL KQVIAGVGAL EQEHAQYKRD
800
801
KFKKTKYGSQ EHPIGDKSFQ NYIRQQSETS THSI                 
834
 

Show the unformatted sequence.

Checksums:
CRC64:97C3467C957DA8A1
MD5:7fb692da65c835673f9cdc0fda9fa3e4

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.