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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ARI5B_HUMAN (Q14865)

Summary

This is the summary of UniProt entry ARI5B_HUMAN (Q14865).

Description: AT-rich interactive domain-containing protein 5B
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 1188 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 81 83
disorder n/a 88 91
low_complexity n/a 248 261
disorder n/a 251 272
disorder n/a 296 305
disorder n/a 311 312
Pfam ARID 320 406
disorder n/a 376 393
disorder n/a 413 570
low_complexity n/a 537 548
disorder n/a 575 618
disorder n/a 635 639
disorder n/a 641 642
disorder n/a 660 675
disorder n/a 677 678
disorder n/a 690 692
low_complexity n/a 694 706
low_complexity n/a 699 717
disorder n/a 728 761
disorder n/a 763 776
disorder n/a 783 789
disorder n/a 799 801
disorder n/a 809 819
disorder n/a 839 945
disorder n/a 948 1011
disorder n/a 1027 1028
disorder n/a 1032 1070
low_complexity n/a 1050 1069

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q14865. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEPNSLQWVG SPCGLHGPYI FYKAFQFHLE GKPRILSLGD FFFVRCTPKD
50
51
PICIAELQLL WEERTSRQLL SSSKLYFLPE DTPQGRNSDH GEDEVIAVSE
100
101
KVIVKLEDLV KWVHSDFSKW RCGFHAGPVK TEALGRNGQK EALLKYRQST
150
151
LNSGLNFKDV LKEKADLGED EEETNVIVLS YPQYCRYRSM LKRIQDKPSS
200
201
ILTDQFALAL GGIAVVSRNP QILYCRDTFD HPTLIENESI CDEFAPNLKG
250
251
RPRKKKPCPQ RRDSFSGVKD SNNNSDGKAV AKVKCEARSA LTKPKNNHNC
300
301
KKVSNEEKPK VAIGEECRAD EQAFLVALYK YMKERKTPIE RIPYLGFKQI
350
351
NLWTMFQAAQ KLGGYETITA RRQWKHIYDE LGGNPGSTSA ATCTRRHYER
400
401
LILPYERFIK GEEDKPLPPI KPRKQENSSQ ENENKTKVSG TKRIKHEIPK
450
451
SKKEKENAPK PQDAAEVSSE QEKEQETLIS QKSIPEPLPA ADMKKKIEGY
500
501
QEFSAKPLAS RVDPEKDNET DQGSNSEKVA EEAGEKGPTP PLPSAPLAPE
550
551
KDSALVPGAS KQPLTSPSAL VDSKQESKLC CFTESPESEP QEASFPSFPT
600
601
TQPPLANQNE TEDDKLPAMA DYIANCTVKV DQLGSDDIHN ALKQTPKVLV
650
651
VQSFDMFKDK DLTGPMNENH GLNYTPLLYS RGNPGIMSPL AKKKLLSQVS
700
701
GASLSSSYPY GSPPPLISKK KLIARDDLCS SLSQTHHGQS TDHMAVSRPS
750
751
VIQHVQSFRS KPSEERKTIN DIFKHEKLSR SDPHRCSFSK HHLNPLADSY
800
801
VLKQEIQEGK DKLLEKRALP HSHMPSFLAD FYSSPHLHSL YRHTEHHLHN
850
851
EQTSKYPSRD MYRESENSSF PSHRHQEKLH VNYLTSLHLQ DKKSAAAEAP
900
901
TDDQPTDLSL PKNPHKPTGK VLGLAHSTTG PQESKGISQF QVLGSQSRDC
950
951
HPKACRVSPM TMSGPKKYPE SLSRSGKPHH VRLENFRKME GMVHPILHRK
1000
1001
MSPQNIGAAR PIKRSLEDLD LVIAGKKARA VSPLDPSKEV SGKEKASEQE
1050
1051
SEGSKAAHGG HSGGGSEGHK LPLSSPIFPG LYSGSLCNSG LNSRLPAGYS
1100
1101
HSLQYLKNQT VLSPLMQPLA FHSLVMQRGI FTSPTNSQQL YRHLAAATPV
1150
1151
GSSYGDLLHN SIYPLAAINP QAAFPSSQLS SVHPSTKL             
1188
 

Show the unformatted sequence.

Checksums:
CRC64:23B7C525B0055330
MD5:b07a96907ddb2fef4978631012087ee1

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
ARID 320 - 406 1IG6 A 3 - 89 Jmol OpenAstexViewer
2OEH A 3 - 89 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.