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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MELT_HUMAN (Q14D04)

Summary

This is the summary of UniProt entry MELT_HUMAN (Q14D04).

Description: Ventricular zone-expressed PH domain-containing protein homolog 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 833 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
low_complexity n/a 58 75
disorder n/a 373 382
coiled_coil n/a 395 415
disorder n/a 423 432
disorder n/a 455 482
disorder n/a 486 501
disorder n/a 520 538
disorder n/a 713 714
Pfam PH 717 819
low_complexity n/a 766 777

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q14D04. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MHQLFRLVLG QKDLSRAGDL FSLDDSEIED SLTEALEQIK IISSSSDYQT
50
51
NNNDQAVVEI CITRITTAIR ETESIEKHAK ALVGLWDSCL EHNLRPFGKD
100
101
EDTPHAKIAS DIMSCILQNY NRPPVMALAI PIAVKFLHRG NKELCRNMSN
150
151
YLSLAAITKA DLLADHTEVI VKSILQGNTM LLRVLPAVYE KQPQPINRHL
200
201
TELLALMSQL EQPEQYHLLR LLHVAAKKKQ LEVVQKCIPF LIGHLKDSTH
250
251
NDIILNILIE IAVYEPVALN SFLPMLKEIG ERFPYLTGQM ARIYGAVGHV
300
301
DEERARSCLT YLVSQLANME HSFHHILLLE IKSITDTFSS ILGPQSRDIF
350
351
RMSNSFTAIA KLLTRQLENT KAGSGRRKIS TEIEFPEKLE ETKLIVTENE
400
401
DHEKLQVKIQ AFEDKINAGS NTPGSIRRYS LGQVSKEERK NIRFNRSKSL
450
451
AFHTMLTKGV GSDDGEDENR GDIPASISLS EIDPLGQGND KLPFKTDTER
500
501
SQLGESSVSY PNIIHIDSEN LSETVKENSQ EETPETTASP IEYQDKLYLH
550
551
LKKNLSKVKA YAMEIGKKIP VPDQCTIEDT VRSCVAKLFF TCSLKGHYCL
600
601
YSKSSFILIS QEPQPWIQIM FLFQQSLFPE PLSIQSHSVQ FLRALWEKTQ
650
651
AGGAHSFETA MMESTFPQQK DLDQVQLHLE EVRFFDVFGF SETAGAWQCF
700
701
MCNNPEKATV VNQDGQPLIE GKLKEKQVRW KFIKRWKTRY FTLAGNQLLF
750
751
QKGKSKDDPD DCPIELSKVQ SVKAVAKKRR DRSLPRAFEI FTDNKTYVFK
800
801
AKDEKNAEEW LQCINVAVAQ AKERESREVT TYL                  
833
 

Show the unformatted sequence.

Checksums:
CRC64:34995B4AB43474A4
MD5:955814e4ab977239b0315be021a41e88

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.