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28  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PSMD6_HUMAN (Q15008)

Summary

This is the summary of UniProt entry PSMD6_HUMAN (Q15008).

Description: 26S proteasome non-ATPase regulatory subunit 6
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 389 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 12
Pfam RPN7 66 239
coiled_coil n/a 67 101
low_complexity n/a 77 91
disorder n/a 81 83
disorder n/a 86 88
Pfam PCI 254 358

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q15008. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPLENLEEEG LPKNPDLRIA QLRFLLSLPE HRGDAAVRDE LMAAVRDNNM
50
51
APYYEALCKS LDWQIDVDLL NKMKKANEDE LKRLDEELED AEKNLGESEI
100
101
RDAMMAKAEY LCRIGDKEGA LTAFRKTYDK TVALGHRLDI VFYLLRIGLF
150
151
YMDNDLITRN TEKAKSLIEE GGDWDRRNRL KVYQGLYCVA IRDFKQAAEL
200
201
FLDTVSTFTS YELMDYKTFV TYTVYVSMIA LERPDLREKV IKGAEILEVL
250
251
HSLPAVRQYL FSLYECRYSV FFQSLAVVEQ EMKKDWLFAP HYRYYVREMR
300
301
IHAYSQLLES YRSLTLGYMA EAFGVGVEFI DQELSRFIAA GRLHCKIDKV
350
351
NEIVETNRPD SKNWQYQETI KKGDLLLNRV QKLSRVINM            
389
 

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Checksums:
CRC64:8843E6684AE91ACD
MD5:8d2e46823d0558af5219c51b87e1bc14

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
PCI 254 - 358 5GJQ R 254 - 358 Jmol OpenAstexViewer
5GJR 5 254 - 358 Jmol OpenAstexViewer
R 254 - 358 Jmol OpenAstexViewer
5L4K R 254 - 358 Jmol OpenAstexViewer
5LN3 R 254 - 358 Jmol OpenAstexViewer
5M32 m 254 - 358 Jmol OpenAstexViewer
5T0C AY 254 - 358 Jmol OpenAstexViewer
BY 254 - 358 Jmol OpenAstexViewer
5T0G Y 254 - 358 Jmol OpenAstexViewer
5T0H Y 254 - 358 Jmol OpenAstexViewer
5T0I Y 254 - 358 Jmol OpenAstexViewer
5T0J Y 254 - 358 Jmol OpenAstexViewer
5VFP Y 254 - 358 Jmol OpenAstexViewer
5VFQ Y 254 - 358 Jmol OpenAstexViewer
5VFR Y 254 - 358 Jmol OpenAstexViewer
5VFS Y 254 - 358 Jmol OpenAstexViewer
5VFT Y 254 - 358 Jmol OpenAstexViewer
5VFU Y 254 - 358 Jmol OpenAstexViewer
5VGZ Y 254 - 358 Jmol OpenAstexViewer
5VHF Y 254 - 358 Jmol OpenAstexViewer
5VHH Y 254 - 358 Jmol OpenAstexViewer
5VHI Y 254 - 358 Jmol OpenAstexViewer
5VHS Y 254 - 358 Jmol OpenAstexViewer
6MSB Y 254 - 358 Jmol OpenAstexViewer
6MSD Y 254 - 358 Jmol OpenAstexViewer
6MSE Y 254 - 358 Jmol OpenAstexViewer
6MSG Y 254 - 358 Jmol OpenAstexViewer
6MSH Y 254 - 358 Jmol OpenAstexViewer
6MSJ Y 254 - 358 Jmol OpenAstexViewer
6MSK Y 254 - 358 Jmol OpenAstexViewer
RPN7 66 - 239 5GJQ R 66 - 239 Jmol OpenAstexViewer
5GJR 5 66 - 239 Jmol OpenAstexViewer
R 66 - 239 Jmol OpenAstexViewer
5L4K R 66 - 239 Jmol OpenAstexViewer
5LN3 R 66 - 239 Jmol OpenAstexViewer
5M32 m 66 - 239 Jmol OpenAstexViewer
5T0C AY 66 - 239 Jmol OpenAstexViewer
BY 66 - 239 Jmol OpenAstexViewer
5T0G Y 66 - 239 Jmol OpenAstexViewer
5T0H Y 66 - 239 Jmol OpenAstexViewer
5T0I Y 66 - 239 Jmol OpenAstexViewer
5T0J Y 66 - 239 Jmol OpenAstexViewer
5VFP Y 66 - 239 Jmol OpenAstexViewer
5VFQ Y 66 - 239 Jmol OpenAstexViewer
5VFR Y 66 - 239 Jmol OpenAstexViewer
5VFS Y 66 - 239 Jmol OpenAstexViewer
5VFT Y 66 - 239 Jmol OpenAstexViewer
5VFU Y 66 - 239 Jmol OpenAstexViewer
5VGZ Y 66 - 239 Jmol OpenAstexViewer
5VHF Y 66 - 239 Jmol OpenAstexViewer
5VHH Y 66 - 239 Jmol OpenAstexViewer
5VHI Y 66 - 239 Jmol OpenAstexViewer
5VHS Y 66 - 239 Jmol OpenAstexViewer
6MSB Y 66 - 239 Jmol OpenAstexViewer
6MSD Y 66 - 239 Jmol OpenAstexViewer
6MSE Y 66 - 239 Jmol OpenAstexViewer
6MSG Y 66 - 239 Jmol OpenAstexViewer
6MSH Y 66 - 239 Jmol OpenAstexViewer
6MSJ Y 66 - 239 Jmol OpenAstexViewer
6MSK Y 66 - 239 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.