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5  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TEAD2_HUMAN (Q15562)

Summary

This is the summary of UniProt entry TEAD2_HUMAN (Q15562).

Description: Transcriptional enhancer factor TEF-4
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 447 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 48
low_complexity n/a 10 42
Pfam TEA 41 110
disorder n/a 98 107
disorder n/a 115 128
disorder n/a 143 149
disorder n/a 159 162
disorder n/a 173 177
low_complexity n/a 180 196
disorder n/a 183 221
low_complexity n/a 200 216
Pfam YBD 226 444
disorder n/a 265 266
low_complexity n/a 308 330

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q15562. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGEPRAGAAL DDGSGWTGSE EGSEEGTGGS EGAGGDGGPD AEGVWSPDIE
50
51
QSFQEALAIY PPCGRRKIIL SDEGKMYGRN ELIARYIKLR TGKTRTRKQV
100
101
SSHIQVLARR KSREIQSKLK DQVSKDKAFQ TMATMSSAQL ISAPSLQAKL
150
151
GPTGPQASEL FQFWSGGSGP PWNVPDVKPF SQTPFTLSLT PPSTDLPGYE
200
201
PPQALSPLPP PTPSPPAWQA RGLGTARLQL VEFSAFVEPP DAVDSYQRHL
250
251
FVHISQHCPS PGAPPLESVD VRQIYDKFPE KKGGLRELYD RGPPHAFFLV
300
301
KFWADLNWGP SGEEAGAGGS ISSGGFYGVS SQYESLEHMT LTCSSKVCSF
350
351
GKQVVEKVET ERAQLEDGRF VYRLLRSPMC EYLVNFLHKL RQLPERYMMN
400
401
SVLENFTILQ VVTNRDTQEL LLCTAYVFEV STSERGAQHH IYRLVRD   
447
 

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Checksums:
CRC64:A9077F55638A3AC7
MD5:69c49eda9b44795e6ed5aaaa44720680

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
YBD 226 - 444 3L15 A 226 - 444 Jmol OpenAstexViewer
B 226 - 444 Jmol OpenAstexViewer
5DQ8 A 226 - 444 Jmol OpenAstexViewer
B 226 - 444 Jmol OpenAstexViewer
5DQE A 226 - 444 Jmol OpenAstexViewer
B 226 - 444 Jmol OpenAstexViewer
5EMV A 226 - 444 Jmol OpenAstexViewer
B 226 - 444 Jmol OpenAstexViewer
5HGU A 226 - 444 Jmol OpenAstexViewer
B 226 - 444 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.