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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TWST1_HUMAN (Q15672)

Summary

This is the summary of UniProt entry TWST1_HUMAN (Q15672).

Description: Twist-related protein 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 202 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 119
low_complexity n/a 4 18
low_complexity n/a 29 70
low_complexity n/a 72 99
Pfam HLH 109 160

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q15672. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MMQDVSSSPV SPADDSLSNS EEEPDRQQPP SGKRGGRKRR SSRRSAGGGA
50
51
GPGGAAGGGV GGGDEPGSPA QGKRGKKSAG CGGGGGAGGG GGSSSGGGSP
100
101
QSYEELQTQR VMANVRERQR TQSLNEAFAA LRKIIPTLPS DKLSKIQTLK
150
151
LAARYIDFLY QVLQSDELDS KMASCSYVAH ERLSYAFSVW RMEGAWSMSA
200
201
SH                                                    
202
 

Show the unformatted sequence.

Checksums:
CRC64:9394E4351BA1D081
MD5:db94d03ca4721f9337e2338d23a65695

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;