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12  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: UB2V2_HUMAN (Q15819)

Summary

This is the summary of UniProt entry UB2V2_HUMAN (Q15819).

Description: Ubiquitin-conjugating enzyme E2 variant 2
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 145 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam UQ_con 14 144
disorder n/a 27 31
disorder n/a 84 85
disorder n/a 128 145

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q15819. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAVSTGVKVP RNFRLLEELE EGQKGVGDGT VSWGLEDDED MTLTRWTGMI
50
51
IGPPRTNYEN RIYSLKVECG PKYPEAPPSV RFVTKINMNG INNSSGMVDA
100
101
RSIPVLAKWQ NSYSIKVVLQ ELRRLMMSKE NMKLPQPPEG QTYNN     
145
 

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Checksums:
CRC64:98D632A1AEC0AADE
MD5:ac7b33be75fc29afcbd91c9c007a639b

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
UQ_con 14 - 143 3VON a 14 - 143 NGL View in InterPro
B 14 - 143 NGL View in InterPro
d 14 - 143 NGL View in InterPro
D 14 - 143 NGL View in InterPro
F 14 - 143 NGL View in InterPro
f 14 - 143 NGL View in InterPro
h 14 - 143 NGL View in InterPro
I 14 - 143 NGL View in InterPro
K 14 - 143 NGL View in InterPro
k 14 - 143 NGL View in InterPro
M 14 - 143 NGL View in InterPro
m 14 - 143 NGL View in InterPro
o 14 - 143 NGL View in InterPro
P 14 - 143 NGL View in InterPro
R 14 - 143 NGL View in InterPro
T 14 - 143 NGL View in InterPro
W 14 - 143 NGL View in InterPro
Y 14 - 143 NGL View in InterPro
5AIT G 14 - 143 NGL View in InterPro
14 - 144 1J74 A 14 - 144 NGL View in InterPro
1J7D A 14 - 144 NGL View in InterPro
1ZGU A 19 - 149 NGL View in InterPro
4NR3 A 14 - 144 NGL View in InterPro
4NRG A 14 - 144 NGL View in InterPro
4NRI A 14 - 144 NGL View in InterPro
4ONL A 14 - 144 NGL View in InterPro
4ONM A 14 - 144 NGL View in InterPro
4ONN A 14 - 144 NGL View in InterPro
4ORH A 14 - 144 NGL View in InterPro
E 14 - 144 NGL View in InterPro
I 14 - 144 NGL View in InterPro
5AIT D 14 - 144 NGL View in InterPro
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TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.