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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: USF2_HUMAN (Q15853)

Summary

This is the summary of UniProt entry USF2_HUMAN (Q15853).

Description: Upstream stimulatory factor 2
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 346 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 54
low_complexity n/a 11 21
disorder n/a 62 67
disorder n/a 69 70
disorder n/a 79 90
disorder n/a 92 96
low_complexity n/a 95 110
disorder n/a 100 101
disorder n/a 115 150
low_complexity n/a 126 144
disorder n/a 152 158
disorder n/a 161 163
disorder n/a 178 186
disorder n/a 192 194
disorder n/a 201 202
disorder n/a 207 249
Pfam HLH 236 291
disorder n/a 266 274
coiled_coil n/a 287 338
disorder n/a 291 292
disorder n/a 294 309
disorder n/a 312 316
disorder n/a 332 346

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q15853. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDMLDPGLDP AASATAAAAA SHDKGPEAEE GVELQEGGDG PGAEEQTAVA
50
51
ITSVQQAAFG DHNIQYQFRT ETNGGQVTYR VVQVTDGQLD GQGDTAGAVS
100
101
VVSTAAFAGG QQAVTQVGVD GAAQRPGPAA ASVPPGPAAP FPLAVIQNPF
150
151
SNGGSPAAEA VSGEARFAYF PASSVGDTTA VSVQTTDQSL QAGGQFYVMM
200
201
TPQDVLQTGT QRTIAPRTHP YSPKIDGTRT PRDERRRAQH NEVERRRRDK
250
251
INNWIVQLSK IIPDCNADNS KTGASKGGIL SKACDYIREL RQTNQRMQET
300
301
FKEAERLQMD NELLRQQIEE LKNENALLRA QLQQHNLEMV GEGTRQ    
346
 

Show the unformatted sequence.

Checksums:
CRC64:78CEFE97AC4C10CF
MD5:63ab1ce63028a4153fa548080ba9bedd

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;