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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: UPP1_HUMAN (Q16831)

Summary

This is the summary of UniProt entry UPP1_HUMAN (Q16831).

Description: Uridine phosphorylase 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 310 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 4 5
Pfam PNP_UDP_1 54 304
low_complexity n/a 134 145

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q16831. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAATGANAEK AESHNDCPVR LLNPNIAKMK EDILYHFNLT TSRHNFPALF
50
51
GDVKFVCVGG SPSRMKAFIR CVGAELGLDC PGRDYPNICA GTDRYAMYKV
100
101
GPVLSVSHGM GIPSISIMLH ELIKLLYYAR CSNVTIIRIG TSGGIGLEPG
150
151
TVVITEQAVD TCFKAEFEQI VLGKRVIRKT DLNKKLVQEL LLCSAELSEF
200
201
TTVVGNTMCT LDFYEGQGRL DGALCSYTEK DKQAYLEAAY AAGVRNIEME
250
251
SSVFAAMCSA CGLQAAVVCV TLLNRLEGDQ ISSPRNVLSE YQQRPQRLVS
300
301
YFIKKKLSKA                                            
310
 

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Checksums:
CRC64:110CF678561E53F3
MD5:9b026298a44fba0e6eb434cadb5e2644

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
PNP_UDP_1 54 - 304 3EUE A 54 - 304 Jmol OpenAstexViewer
3EUF A 54 - 304 Jmol OpenAstexViewer
B 54 - 304 Jmol OpenAstexViewer
C 54 - 304 Jmol OpenAstexViewer
D 54 - 304 Jmol OpenAstexViewer
3NBQ A 54 - 304 Jmol OpenAstexViewer
B 54 - 304 Jmol OpenAstexViewer
C 54 - 304 Jmol OpenAstexViewer
D 54 - 304 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.