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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: KDM5_CAEEL (Q23541)

Summary

This is the summary of UniProt entry KDM5_CAEEL (Q23541).

Description: Lysine-specific demethylase rbr-2
Source organism: Caenorhabditis elegans (NCBI taxonomy ID 6239)
Length: 1477 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 35
low_complexity n/a 9 22
Pfam JmjN 57 90
Pfam ARID 123 214
disorder n/a 213 313
coiled_coil n/a 218 238
low_complexity n/a 273 286
low_complexity n/a 309 318
Pfam PHD 321 371
Pfam JmjC 501 617
Pfam zf-C5HC2 709 761
Pfam PLU-1 774 1132
disorder n/a 778 779
disorder n/a 781 786
disorder n/a 844 849
disorder n/a 851 859
low_complexity n/a 899 919
disorder n/a 1296 1301
disorder n/a 1380 1402
low_complexity n/a 1389 1398
disorder n/a 1474 1477

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q23541. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MRARRQENSI STPSAPSTST SPRKKASIGN SRSKNHGSKM EMYDQFYKKF
50
51
VRPPMAPIYY PTEEEFSDPI EYVAKIRHEA EKFGVVKIVP PANFKPPFAI
100
101
DKEAFTFRPR TQKLNEVEAI VKEKHTFIDR LINFNRYSGL TFEFPVDRDG
150
151
NIVDLYRLHR IVQNFGGCEE VNEDEKWRDV AREYLPKEQM ARGVPSAFIN
200
201
LIRSHYNLHI EPFNRNLKEK AMKNDDESDD EMEELKHKYQ HHHGTMRTEI
250
251
EVPNDKTTEG GEDECPVSMQ SGRRRSKNKK ASSSRKTLGT SSKKNSTRGR
300
301
KNKKKAEGDD DDDEDPMDQV FCVACNEGKD EDLLLLCDID GCNNGRHTYC
350
351
CDPVLDEVPE GEWRCPKCIE SEDAKIGLDW GFYDADTEYN LNSFTEFANK
400
401
WKCDYFGVKD VSQVSCDAVE RSFWKNVISH ENPVSVKYGA DLITSRVGSG
450
451
FPRKEDKHTG PDLKLKQQYA SHAWNLNNMP VLRESVLSHF NTGISGMMVP
500
501
WVYVGMCFST FCWHTEDHWT YSVNYNHFGE RKIWYGVGGE DAEKFEDALK
550
551
KIAPGLTGRQ RDLFHHMTTA ANPHLLRSLG VPIHSVHQNA GEFVITFPRA
600
601
YHAGFNEGLN FAEAVNFAPI DWLSKGRECV ESYSNVRRYL VFSHDELLFK
650
651
MVEAMDKLGI SMSLATHEEL IRIYEKQKML RELLARLGVS NRQMQQVMFE
700
701
KIPDEQRSCR FCKTTLFMCA LVCNKHKKMT CVEHHDHLCN SCTTKDYRYQ
750
751
YRFELDQLNN MCDELGKRTV NYNGWKEESD EMLEEEGKPK LERIEEFIDS
800
801
AKQNKYPQTD QVHKLITIRH TAKSAIEKAN QLLFKKVRTR TKTRCQRADT
850
851
RTDTEGVRSL IEQMQAMDCN LTVIIDKLEK WMEQVEMWRN RAKDAIYREQ
900
901
EYSKEEIEKI IEEGDEYDIK LEEIDELRKV IQMKDWSDRA RKVTTWKATP
950
951
DMEKDIDFEY KLRYASSDIL SLIRDSPRNP TDGTSKLVFE LQQMLRDANT
1000
1001
LEVIANNFCE NPALDQLQSI WQSLRETDWF YEKYINMVRY EIIHVAKIKS
1050
1051
MIDAAIPVLS EFDLKTQLQK IVNVEITLSK AAEISKAFET SKCLNGSEEH
1100
1101
LGILDMISTM NAFTQRIAIL FKPNNAYHNL FEILSERDDL TPLAEGQTIP
1150
1151
LYFQGGAVHP SDEWHQMKEF ESLDQIVHHQ SSLREMQMRI FEKVKQANSA
1200
1201
RGLEACSCLG FNKSDDSEST LTCIMCDSEF HVRCCEWSPF LEKLPEGCFL
1250
1251
CVRCLRGQRP VIDDVTTALN GTPSGCLETH LVRNLIQKTR GITQNLMEAA
1300
1301
NKRKSGESSD DICKIALFDW LSCEILNPNG LPKARELISE FYMEYLQKQS
1350
1351
SAALELKNRP VRSKPSVSLF DPKITAKRKR PSVSHKETSK KSRKRQSQAS
1400
1401
PSEYYEDESE FKSCQARACL KPYGDSVNWV MCEAGCKNWF HVICLGFTLR
1450
1451
EINDMHEYRC SSCLDHADSP TSSVSTD                         
1477
 

Show the unformatted sequence.

Checksums:
CRC64:E2539E727C6E72D7
MD5:98bccddf699e2a448ed350efaa946322

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;