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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RBF_DROME (Q24472)

Summary

This is the summary of UniProt entry RBF_DROME (Q24472).

Description: Retinoblastoma family protein
Source organism: Drosophila melanogaster (Fruit fly) (NCBI taxonomy ID 7227)
Length: 845 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 6
disorder n/a 11 13
Pfam DUF3452 90 228
disorder n/a 349 363
disorder n/a 369 373
disorder n/a 375 376
Pfam RB_A 376 560
Pfam RB_B 581 705
disorder n/a 722 745
disorder n/a 747 754
disorder n/a 763 764
disorder n/a 777 845
low_complexity n/a 828 845

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q24472. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSEPDPQELG AEVVSGLVAT SDDRLEMINA EYTNLCRDLN MDRQTELQGY
50
51
ETYLEVSQRC SMEGTASHWM CCAIYTACRR TSTPTVTGQN AVVKGNCVSL
100
101
NNLLRCCKMS IYEFKTKIKQ WCDMANLPQE FVNEIEDLDR KFSITFMLHK
150
151
RFRIIMDMIF SCPPNEKKHS KYISLHGNHA HGKCSYIKLD DICWRLFLCA
200
201
KNQKPSNTVD LVTSYNLMIC CIDLIYNNVL AEKRTDLINP KFEGLPSNWT
250
251
ELDFRHNPHC ILSNFCDMTE EAKAMKATTF RQIMSSFFQA STIYGNKDTM
300
301
LGLLANENFE RNLKSLNISY EQYVLSVGEF DERILSAYDA GEHTALNDQS
350
351
LRPPVTPLTR KQDLPAQPAM AGDKFEPVRN ATNNVKQLSA FGRITEPTDF
400
401
VKQAGEEVIA KLLSIIEEIE QKFLAKYPST EAKSRFQLAK SFFFYLLDQI
450
451
LQAEIRNKPD IDLKRLLVQK VSLVIFNITL MACCVELVLE AYKTELKFPW
500
501
VLDCFSISAF EFQKIIEIVV RHGSHEGCLN RSLIKHLNSI EETCLERLAW
550
551
ARNSTVWEMI ASAQLPLPTW LMVNLDRAAG PLQIFLRKVY LLGWLRIQKL
600
601
CSELSLCEKT PESIWHIFEH SITHETELMK DRHLDQNIMC AIYIYIRVKR
650
651
MEDPKFSDIM RAYRNQPQAV NSVYREVFID INEDGEPKVK DIIHFYNHTY
700
701
VPLMRQFVID YLNVTPDVSG RASDLQLSPH PKERAAQPKK VTQSHSLFVS
750
751
QMSKNEIQQS PNQMVYSFCR SPAKDLQAMN EKVRGGKRML SFGDEPGLGT
800
801
MAETKRSKIS QVKAVMDDPE LQSAEQQTAV TTEGCVGGEG GEHET     
845
 

Show the unformatted sequence.

Checksums:
CRC64:C7AF38592C14FAD2
MD5:a7decdc1453827dd633d629f251420ce

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;