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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: K1109_HUMAN (Q2LD37)

Summary

This is the summary of UniProt entry K1109_HUMAN (Q2LD37).

Description: Uncharacterized protein KIAA1109
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 5005 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
transmembrane n/a 27 46
transmembrane n/a 67 85
disorder n/a 163 187
disorder n/a 306 317
disorder n/a 622 624
disorder n/a 633 635
disorder n/a 675 676
disorder n/a 678 679
disorder n/a 687 689
disorder n/a 691 692
disorder n/a 694 726
low_complexity n/a 696 715
low_complexity n/a 766 778
disorder n/a 782 798
disorder n/a 1096 1097
low_complexity n/a 1126 1137
low_complexity n/a 1153 1165
disorder n/a 1193 1195
disorder n/a 1201 1208
disorder n/a 1218 1312
low_complexity n/a 1225 1239
disorder n/a 1314 1316
disorder n/a 1339 1370
disorder n/a 1373 1383
low_complexity n/a 1380 1390
low_complexity n/a 1388 1401
disorder n/a 1397 1425
disorder n/a 1427 1456
disorder n/a 1462 1463
disorder n/a 1480 1481
disorder n/a 1486 1495
disorder n/a 1521 1547
low_complexity n/a 1540 1546
disorder n/a 1570 1572
disorder n/a 1574 1609
low_complexity n/a 1590 1606
disorder n/a 1611 1612
disorder n/a 1676 1714
disorder n/a 1741 1747
disorder n/a 1770 1798
disorder n/a 1800 1810
low_complexity n/a 1809 1820
disorder n/a 1872 1881
disorder n/a 1924 1991
low_complexity n/a 1980 1994
disorder n/a 2168 2192
low_complexity n/a 2180 2190
disorder n/a 2196 2197
disorder n/a 2202 2203
disorder n/a 2213 2244
disorder n/a 2247 2252
disorder n/a 2262 2289
disorder n/a 2291 2292
disorder n/a 2305 2339
low_complexity n/a 2335 2348
disorder n/a 2362 2387
disorder n/a 2393 2394
disorder n/a 2397 2428
disorder n/a 2488 2501
disorder n/a 2593 2617
low_complexity n/a 2613 2625
disorder n/a 2619 2697
low_complexity n/a 2621 2636
low_complexity n/a 2632 2655
coiled_coil n/a 2635 2655
disorder n/a 2724 2754
disorder n/a 2756 2764
disorder n/a 2849 2854
disorder n/a 2910 2914
disorder n/a 2923 2968
disorder n/a 3004 3006
disorder n/a 3013 3015
disorder n/a 3044 3046
disorder n/a 3136 3141
low_complexity n/a 3467 3479
disorder n/a 3498 3499
disorder n/a 3501 3529
disorder n/a 3557 3558
disorder n/a 3571 3572
disorder n/a 3592 3593
disorder n/a 3616 3665
disorder n/a 3671 3675
disorder n/a 3677 3681
disorder n/a 3686 3748
low_complexity n/a 3716 3741
disorder n/a 3757 3759
disorder n/a 3771 3785
low_complexity n/a 3815 3836
disorder n/a 3816 3819
disorder n/a 3821 3864
disorder n/a 3886 3954
low_complexity n/a 3921 3929
low_complexity n/a 3940 3947
disorder n/a 4000 4024
low_complexity n/a 4023 4037
disorder n/a 4026 4029
low_complexity n/a 4040 4048
disorder n/a 4087 4140
low_complexity n/a 4117 4148
disorder n/a 4172 4193
disorder n/a 4287 4307
disorder n/a 4314 4317
disorder n/a 4326 4394
low_complexity n/a 4358 4379
Pfam FSA_C 4384 4902
disorder n/a 4424 4431
disorder n/a 4433 4448
disorder n/a 4450 4454
disorder n/a 4479 4482
disorder n/a 4487 4496
disorder n/a 4611 4612
disorder n/a 4735 4749
disorder n/a 4772 4781
disorder n/a 4783 4784
disorder n/a 4787 4790
low_complexity n/a 4789 4800
disorder n/a 4822 4825
disorder n/a 4828 4837
disorder n/a 4896 4902
Pfam FSA_C 4898 4989
disorder n/a 4909 4910
low_complexity n/a 4992 5003
disorder n/a 4994 5005

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q2LD37. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDQRKNESIV PSITQLEDFL TEHNSNVVWL LVATILSCGW IIYLTYYNSR
50
51
NVGLILTLVL NRLYKHGYIH IGSFSFSVLS GKVMVREIYY ITEDMSIRIQ
100
101
DGFIIFRWWK MYNPKQKQHD PKAETRLYIT VNDFEFHVYN RSDLYGRLQE
150
151
LFGLEPTIIP PKKDDDKTRE IGRTRTQSKI ERVKVKTESQ DPTSSWRSLI
200
201
PVIKVNVSTG RLAFGNHYQP QTLCINFDDA FLTYTTKPPS SHLDQFMHIV
250
251
KGKLENVRVM LVPSPRYVGL QNDEPPRLMG EGFVVMQSND VDIYYYMDEP
300
301
GLVPEETEEN IEGEMSSEDC KLQDLPPCWG LDIVCGKGTD FNYGPWADRQ
350
351
RDCLWKFFFP PDYQVLKVSE IAQPGRPRQI LAFELRMNII ADATIDLLFT
400
401
KNRETNAVHV NVGAGSYLEI NIPMTVEENG YTPAIKGQLL HVDATTSMQY
450
451
RTLLEAEMLA FHINASYPRI WNMPQTWQCE LEVYKATYHF IFAQKNFFTD
500
501
LIQDWSSDSP PDIFSFVPYT WNFKIMFHQF EMIWAANQHN WIDCSTKQQE
550
551
NVYLAACGET LNIDFSLPFT DFVPATCNTK FSLRGEDVDL HLFLPDCHPS
600
601
KYSLFMLVKN CHPNKMIHDT GIPAECQSGQ KTVKPKWRNV TQEKSGWVEC
650
651
WTVPSVMLTI DYTWHPIYPQ KADEQLKQSL SEMEETMLSV LRPSQKTSDR
700
701
VVSSPSTSSR PPIDPSELPP DKLHVEMELS PDSQITLYGP LLNAFLCIKE
750
751
NYFGEDDMYM DFEEVISSPV LSLSTSSSSG WTAVGMENDK KENEGSAKSI
800
801
HPLALRPWDI TVLVNLYKVH GRLPVHGTTD GPECPTAFLE RLCFEMKKGF
850
851
RETMLQLILS PLNVFVSDNY QQRPPVDEVL REGHINLSGL QLRAHAMFSA
900
901
EGLPLGSDSL EYAWLIDVQA GSLTAKVTAP QLACLLEWGQ TFVFHVVCRE
950
951
YELERPKSVI ICQHGIDRRF CESKLSCIPG PCPTSDDLKY TMIRLAVDGA
1000
1001
DIYIVEHGCA TNIKMGAIRV ANCNLHNQSV GEGISAAIQD FQVRQYIEQL
1050
1051
NNCRIGLQPA VLRRAYWLEA GSANLGLITV DIALAADHHS KHEAQRHFLE
1100
1101
THDARTKRLW FLWPDDILKN KRCRNKCGCL GGCRFFGGTV TGLDFFKLEE
1150
1151
LTPSSSSAFS STSAESDMYY GQSLLQPGEW IITKEIPKII DGNVNGMKRK
1200
1201
EWENKSVGIE VERKTQHLSL QVPLRSHSSS SSSEENSSSS AAQPLLAGEK
1250
1251
ESPSSVADDH LVQKEFLHGT KRDDGQASIP TEISGNSPVS PNTQDKSVGQ
1300
1301
SPLRSPLKRQ ASVCSTRLGS TKSLTAAFYG DKQPVTVGVQ FSSDVSRSDE
1350
1351
NVLDSPKQRR SFGSFPYTPS ADSNSFHQYR SMDSSMSMAD SEAYFSAAEE
1400
1401
FEPISSDEGP GTYPGRKKKK KQTQQIDYSR GSIYHSVEGP LTGHGESIQD
1450
1451
SRTLPFKTHP SQASFVSALG GEDDVIEHLY IVEGEKTVES EQITPQQPVM
1500
1501
NCYQTYLTQF QVINWSVKHP TNKRTSKSSL HRPLDLDTPT SEESSSSFEQ
1550
1551
LSVPTFKVIK QGLTANSLLD RGMQLSGSTS NTPYTPLEKK LADNTDDETL
1600
1601
TEEWTLDQPV SQTRTTAIVE VKGTVDIVLT PLVAEALDRY IEAMVHCAST
1650
1651
RHPAAIVDDL HAKVLREAVQ NSKTTFSENL SSKQDIRGTK TEQSTIGTTN
1700
1701
QGQAQTNLTM KQDNVTIKGL QTNVSIPKVN LCLLQASVEE SPTTAPSRSV
1750
1751
THVSLVALCF DRIATQVRMN RGVVEETSNN AEPGRTSNFD RYVHATKMQP
1800
1801
QSSGSLRSNA GAEKGKEIAA KLNIHRVHGQ LRGLDTTDIG TCAITAIPFE
1850
1851
KSKVLFTLEE LDEFTFVDET DQQAVPDVTR IGPSQEKWGW IMFECGLENL
1900
1901
TIKGGRQSGA VLYNSFGIMG KASDTERGGV LTSNNSSDSP TGSGYNTDVS
1950
1951
DDNLPCDRTS PSSDLNGNSV SDEQDEGVES DDLKKDLPLM PPPPDSCSMK
2000
2001
LTIKEIWFSF AAPTNVRSHT HAFSRQLNLL STATPAVGAW LVPIDQLKSS
2050
2051
LNKLETEGTL RICAVMGCIM TEALENKSVH FPLRSKYNRL TKVARFLQEN
2100
2101
PSCLLCNILH HYLHQANYSI IDDATMSDGL PALVTLKKGL VALARQWMKF
2150
2151
IVVTPAFKGV SLHRPAQPLK PQIAMDHEHE DGLGLDNGGG LQSDTSADGA
2200
2201
EFEFDAATVS EHTMLLEGTA NRPPPGSSGP VTGAEIMRKL SKTHTHSDSA
2250
2251
LKIKGIHPYH SLSYTSGDTA TDSPVHVGRA GMPVKDSPRK ESLLSYLTGS
2300
2301
FPSLHNLLEG TPQRSSAAVK SSSLTRTGNT VATDMLSEHP LLSEPSSVSF
2350
2351
YNWMSNAVGN RGSVLQESPV TKSGHNSLPT GVAPNLPTIP SASDFNTVLS
2400
2401
SDQNTLDGTH SQHSTSQDDV AGVEEANQGF PAVQLADAQV VFKPLLSHTG
2450
2451
IQSQDTMPFC YRMYFGEHLS FSGTLDCLRA DIVDSDTAKE RKGKRARRQG
2500
2501
HVNLPPLEFK PALMLGTFSI SAVVMEKSVC TPQNSTSALS FHDLSKRYYN
2550
2551
TFHCNFTISC QSISQHVDMA LVRLIHQFST MIDDIKATQT DIKLSRYTAG
2600
2601
SASPTPTFKT RKHRDFRSSD FSRSSRGSLN GGNRVNNAKN KRTNNENNKK
2650
2651
ESRNKNSLGR SERRTSKVSR KGSKDVVDHM TIHMDDSDSI TVSEQSEPSA
2700
2701
ECWQNMYKLL NFYSLISDPT GILEKSSETF GPAGVRSPTE PTCKVVFENE
2750
2751
QDNSSLTKTQ RKRSLVTSEP QHVTLIVFGI GMVNRTHLEA DIGGLTMESE
2800
2801
LKRIHGSFTL KEKMKDVLHQ KMTETCATAH IGGVNIVLLE GITPNIQLED
2850
2851
FPTSPTSTAK QEFLTVVKCS IAKSQALYSA QRGLKTNNAA VFKVGAISIN
2900
2901
IPQHPATLHS MMVRSSHQLS KQISDLIRQP STAPQPVKED IATPLPSEKT
2950
2951
PTSVNQTPVE TNEFPQLPEG LEKKPIVLKF SAMLDGIAIG AALLPSLKAE
3000
3001
YKMGRMRSHG MTGAQTRFTF ELPNHRLRFT SKVSATDMST IPPSASLNLP
3050
3051
PVTMSGKYIM EEHDSYSDQV WSIDELPSKQ GYYLQGNYLR CVAEVGSFEH
3100
3101
NLTTDLLNHL VFVQKVFMKE VNEVIQKVSG GEQPIPLWNE HDGTADGDKP
3150
3151
KILLYSLNLQ FKGIQVTATT PSMRAVRFET GLIELELSNR LQTKASPGSS
3200
3201
SYLKLFGKCQ VDLNLALGQI VKHQVYEEAG SDFHQVAYFK TRIGLRNALR
3250
3251
EEISGSSDRE AVLITLNRPI VYAQPVAFDR AVLFWLNYKA AYDNWNEQRM
3300
3301
ALHKDIHMAT KEVVDMLPGI QQTSAQAFGT LFLQLTVNDL GICLPITNTA
3350
3351
QSNHTGDLDT GSALVLTIES TLITACSSES LVSKGHFKNF CIRFADGFET
3400
3401
SWDDWKPEIH GDLVMNACVV PDGTYEVCSR TTGQAAAESS SAGTWTLNVL
3450
3451
WKMCGIDVHM DPNIGKRLNA LGNTLTTLTG EEDIDDIADL NSVNIADLSD
3500
3501
EDEVDTMSPT IHTEATDYRR QAASASQPGE LRGRKIMKRI VDIRELNEQA
3550
3551
KVIDDLKKLG ASEGTINQEI QRYQQLESVA VNDIRRDVRK KLRRSSMRAA
3600
3601
SLKDKWGLSY KPSYSRSKSI SASGRPPLKR MERASSRVGE TEELPEIRVD
3650
3651
AASPGPRVTF NIQDTFPEET ELDLLSVTIE GPSHYSSNSE GSCSVFSSPK
3700
3701
TPGGFSPGIP FQTEEGRRDD SLSSTSEDSE KDEKDEDHER ERFYIYRKPS
3750
3751
HTSRKKATGF AAVHQLFTER WPTTPVNRSL SGTATERNID FELDIRVEID
3800
3801
SGKCVLHPTT LLQEHDDISL RRSYDRSSRS LDQDSPSKKK KFQTNYASTT
3850
3851
HLMTGKKVPS SLQTKPSDLE TTVFYIPGVD VKLHYNSKTL KTESPNASRG
3900
3901
SSLPRTLSKE SKLYGMKDSA TSPPSPPLPS TVQSKTNTLL PPQPPPIPAA
3950
3951
KGKGSGGVKT AKLYAWVALQ SLPEEMVISP CLLDFLEKAL ETIPITPVER
4000
4001
NYTAVSSQDE DMGHFEIPDP MEESTTSLVS SSTSAYSSFP VDVVVYVRVQ
4050
4051
PSQIKFSCLP VSRVECMLKL PSLDLVFSSN RGELETLGTT YPAETLSPGG
4100
4101
NATQSGTKTS ASKTGIPGSS GLGSPLGRSR HSSSQSDLTS SSSSSSGLSF
4150
4151
TACMSDFSLY VFHPYGAGKQ KTAVSGLTPG SGGLGNVDEE PTSVTGRKDS
4200
4201
LSINLEFVKV SLSRIRRSGG ASFFESQSVS KSASKMDTTL INISAVCDIG
4250
4251
SASFKYDMRR LSEILAFPRA WYRRSIARRL FLGDQTINLP TSGPGTPDSI
4300
4301
EGVSQHLSPE SSRKAYCKTW EQPSQSASFT HMPQSPNVFN EHMTNSTMSP
4350
4351
GTVGQSLKSP ASIRSRSVSD SSVPRRDSLS KTSTPFNKSN KAASQQGTPW
4400
4401
ETLVVFAINL KQLNVQMNMS NVMGNTTWTT SGLKSQGRLS VGSNRDREIS
4450
4451
MSVGLGRSQL DSKGGVVGGT IDVNALEMVA HISEHPNQQP SHKIQITMGS
4500
4501
TEARVDYMGS SILMGIFSNA DLKLQDEWKV NLYNTLDSSI TDKSEIFVHG
4550
4551
DLKWDIFQVM ISRSTTPDLI KIGMKLQEFF TQQFDTSKRA LSTWGPVPYL
4600
4601
PPKTMTSNLE KSSQEQLLDA AHHRHWPGVL KVVSGCHISL FQIPLPEDGM
4650
4651
QFGGSMSLHG NHMTLACFHG PNFRSKSWAL FHLEEPNIAF WTEAQKIWED
4700
4701
GSSDHSTYIV QTLDFHLGHN TMVTKPCGAL ESPMATITKI TRRRHENPPH
4750
4751
GVASVKEWFN YVTATRNEEL NLLRNVDANN TENSTTVKNS SLLSGFRGGS
4800
4801
SYNHETETIF ALPRMQLDFK SIHVQEPQEP SLQDASLKPK VECSVVTEFT
4850
4851
DHICVTMDAE LIMFLHDLVS AYLKEKEKAI FPPRILSTRP GQKSPIIIHD
4900
4901
DNSSDKDRED SITYTTVDWR DFMCNTWHLE PTLRLISWTG RKIDPVGVDY
4950
4951
ILQKLGFHHA RTTIPKWLQR GVMDPLDKVL SVLIKKLGTA LQDEKEKKGK
5000
5001
DKEEH                                                 
5005
 

Show the unformatted sequence.

Checksums:
CRC64:8EF3E5E73AF2A37D
MD5:c611fbcbfb4885a88bc9fb976b413ae3

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.