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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: Q387I8_TRYB2 (Q387I8)

Summary

This is the summary of UniProt entry Q387I8_TRYB2 (Q387I8).

Description: DNA-directed RNA polymerase subunit beta {ECO:0000256|RuleBase:RU363031}
Source organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1) (NCBI taxonomy ID 185431)
Length: 1596 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
disorder n/a 1 49
low_complexity n/a 6 20
low_complexity n/a 24 41
disorder n/a 74 81
disorder n/a 283 290
disorder n/a 296 297
coiled_coil n/a 302 322
Pfam RNA_pol_Rpb2_1 365 807
disorder n/a 676 682
Pfam RNA_pol_Rpb2_3 840 905
Pfam RNA_pol_Rpa2_4 956 1026
low_complexity n/a 978 991
Pfam RNA_pol_Rpb2_6 1089 1488
disorder n/a 1227 1230
disorder n/a 1333 1334
disorder n/a 1468 1491
low_complexity n/a 1483 1495
Pfam RNA_pol_Rpb2_7 1490 1592

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q387I8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSTKNSVVGS ASGSHASTAG ETVTSTRSGT SSRHSRQRRQ QYDYVKNPSE
50
51
PMTAMERLKL VRCSIARLRY LGERHRHTSK LDTTGGDRLL SFFEGLRKRV
100
101
LKLEYNPRVV AKSKVGAPKH LDYIRGHANA LLGEASTIIS ECEQAMDRSE
150
151
AVYEGLAYHQ LQDTHRELEN LVGLLSGAPS DMESAGSLKL LADLVSPHVA
200
201
EFDAFAEQRV PEFLQELKNE GFLFSSVIND SQQPANAIGL LSVFIVDVAI
250
251
GVRPGRSARL VIQHALHNLA RLKSRVDKAD LTLGAEEDSS NNEHHRMQSL
300
301
EFEVIRGRLR EAKEELERIR DKWDHDEGDI FSRAGTGVQG LQSIIDAKRV
350
351
KESTVIEEAQ AIHDRTVYAC LPFASPQYCR IRSETYSQPC HVRVGFKFVA
400
401
KGDGSVSRTK TQLIYNLMPE FLILMRQQGI APSDQERFAT LAPSKYELWL
450
451
SLGELPEMVL GARCALRGVN QRLDHFRALE EQKEVGGYFV LRGGERILRN
500
501
LILQRCNVPL NIERERFATV DSFFSPRAVI IRCKRPSGLT VQNYFYYATK
550
551
GEVIFTFARR VVWNIPALLV LSALNTRHRT SLDIYKLLTI GLTNGRSPHA
600
601
ARVEALLQHH SQMPYSTLDN FLDYLAVVGL MYRRYHESSF IFRFLPQYHT
650
651
SFATQHDAWY GLFMLRRHML PHLNTAEATP DLPPTATSRE IREWLSTGLQ
700
701
EELAAKFDAL IGILRQLLVF NDGATGNQGN DVLAYQEVFT VSQVLIGAFE
750
751
VSLMKTMGAV TFRMAGQLSP EIFQATMCLA ETPIREAANT LEKLNQLLEY
800
801
SCRNNGPDPL ITLNRLLLTG NFALDREEDF YSPQTAGWAV MTEHLNFYRS
850
851
FEQLMCVHRG KSIAEMRSSD VRRYPCEAYG FICMVHSPDG EDCGVLNHLS
900
901
ISTVLSASPR VGSSQYKILL AFIEEELKNV RNTTSLISCV DQLVGTVPVW
950
951
LEGRLLGYLS PNEALSASKA LTQKKALRSR GVVGVTGIVR RDSISSLNTM
1000
1001
EVVYIPPGSK DPMGLYIFYQ YGRLMRPVLQ IESPSRGGDL PFPVVYLGTW
1050
1051
EQSWRDIAAV PSDLFDGFDQ LRRKYEFMEQ NGFNILSFTS STIPFFEHNC
1100
1101
SPRNLFQCGL SKQTAGTQLQ TQAWRRDAKL FRMYYPQRYI SRTLPMDYFG
1150
1151
LDDVSLGVNA VVAILAYTGY DLDDAMILNS TAKQFGMLNA GVTVAKIVKA
1200
1201
SGKGDSNDVF VFHNCLPDGQ PFTPELDRHG LPKKRAVPNA TAYFSFDTDH
1250
1251
KYPSLRDSSA VYCCAKRFEY IDPLTNEKTY EYTRHQITKW RHFDKGEDAW
1300
1301
VHSVIPLTYD GPDPTSVLVL FRIPRPPVIG DKFSSRHGQK GTLPLDIRSH
1350
1351
DLPFSTRDGI TPDIIINPHA FPSRMTVGMV LEMMGAKLGC IQGRLCDHSA
1400
1401
WSVIDEQPRS AKTIGDALEA LGYNRYGREK LIDGITGEEI EAEVLVGISG
1450
1451
YQRLRHMVSD KWQARARTDS HTHRAVTKTG QPVKGRKRHG GVRVGEMERD
1500
1501
ALLSHGVAEV VIDRLLHVSD KTKAFICVEC GSMLSIYERH ATEYSTWKTC
1550
1551
KFCSAGLHET DDTIAFVEIP QVLRLWATEL TSVGIRVVLK TSETSL    
1596
 

Show the unformatted sequence.

Checksums:
CRC64:752E09C31486729B
MD5:379baf03998a9d4ee9322048c244abf6

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;