Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: GFOD2_HUMAN (Q3B7J2)

Summary

This is the summary of UniProt entry GFOD2_HUMAN (Q3B7J2).

Description: Glucose-fructose oxidoreductase domain-containing protein 2 EC=1.-.-.-
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 385 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
sig_p n/a 1 16
Pfam GFO_IDH_MocA 6 119
Pfam GFO_IDH_MocA_C 134 281
low_complexity n/a 169 180
disorder n/a 325 326
disorder n/a 329 330
disorder n/a 361 368
disorder n/a 371 380

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q3B7J2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKMLPGVGVF GTGSSARVLV PLLRAEGFTV EALWGKTEEE AKQLAEEMNI
50
51
AFYTSRTDDI LLHQDVDLVC ISIPPPLTRQ ISVKALGIGK NVVCEKAATS
100
101
VDAFRMVTAS RYYPQLMSLV GNVLRFLPAF VRMKQLISEH YVGAVMICDA
150
151
RIYSGSLLSP SYGWICDELM GGGGLHTMGT YIVDLLTHLT GRRAEKVHGL
200
201
LKTFVRQNAA IRGIRHVTSD DFCFFQMLMG GGVCSTVTLN FNMPGAFVHE
250
251
VMVVGSAGRL VARGADLYGQ KNSATQEELL LRDSLAVGAG LPEQGPQDVP
300
301
LLYLKGMVYM VQALRQSFQG QGDRRTWDRT PVSMAASFED GLYMQSVVDA
350
351
IKRSSRSGEW EAVEVLTEEP DTNQNLCEAL QRNNL                
385
 

Show the unformatted sequence.

Checksums:
CRC64:D516EE4CC5CF5667
MD5:6066bffeec44cc8650594bcc4c5e9563

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;