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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RPAP1_RAT (Q3T1I9)

Summary

This is the summary of UniProt entry RPAP1_RAT (Q3T1I9).

Description: RNA polymerase II-associated protein 1
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 1400 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 19
disorder n/a 29 109
low_complexity n/a 59 74
disorder n/a 113 117
disorder n/a 119 150
disorder n/a 152 250
Pfam RPAP1_N 225 270
disorder n/a 255 333
disorder n/a 346 362
Pfam RPAP1_C 364 430
disorder n/a 365 368
disorder n/a 380 387
low_complexity n/a 383 392
low_complexity n/a 443 457
low_complexity n/a 451 465
low_complexity n/a 468 480
disorder n/a 504 536
low_complexity n/a 507 517
low_complexity n/a 731 747
disorder n/a 1030 1034
low_complexity n/a 1088 1099
low_complexity n/a 1094 1105
low_complexity n/a 1373 1390

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q3T1I9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MMLSRPKPGE SEVDLLRFQS QFLEAGAAPA VQLVKGSRRR GDAHPDQLPP
50
51
QDHRDVVMLD SLPDLPPALL PAPSKRARPS PGRPLPHDED PEERLNRHDE
100
101
HITAVLSKIV ERDTSSVTVT LPVPSGVAFP PVFHRSQERQ VKPAASSKRS
150
151
IFAQEIAARR VSDNRAPSAE QVVPSPDAPE GAVPCETPSS KDRGSQLPGR
200
201
SHSFHRPNLI TGKGLRSQAA VQEVQTIHEE NVARLQAMDP EEILKEQQQL
250
251
LAQLDPSLVA FLRAHNHTRE QTETKATKEQ NPERPSVPVS KEEPIMSTCT
300
301
GESGTRDKLE DKLEDKLQPR TPALKLPMTP NKEWLHMDTV ELEKLHWTQD
350
351
LPPLRRQQTQ ERMQARFSLQ GELLEPDVDL PTHLGLHHHG EEAERAGYSL
400
401
QELFHLTRSQ VSQQRALALH VLSHIVGRAQ AGEFGDRLVG SVLRLLLDAG
450
451
FLFLLRFSLD DRIDSVIAAA VRALRALLVA PGDEELLDST FSWYHGASVF
500
501
PMMPSHDDKE DEDEDEELTK EKVNRKTPEE GSRPPPDLAR HDVIKGLLAT
550
551
NLLPRFRYVL EVTCPGPSVV LDILAVLIRL ARHSLESAMR VLECPRLMET
600
601
IVREFLPTSW SPIGVGPAPS LYKVPCAAAM KLLRVLASAG RNIAARLLSS
650
651
FDVRSRLCRF IAEAPRDLAL PFEEAEILTT EAFRLWAVAA SYGQGGDLYR
700
701
ELYPVLMRAL QTLPPELSTH PLQPLSMQRM ASLLTLLTQL TLAASTQPEA
750
751
TSGSVESCVV AIPSSITWTH VSGLKPLVEP CLKQTLKFLR RPDVWNALGP
800
801
VPSACLLFLG AYYQTWSQQS GLCPEDWLQD MERFLDEFLL PLLSQPPLGR
850
851
MWDSLRDCSP LCNPLSCAST PEALPSLVSL GCAGGCPPLS VAGSASPFPF
900
901
LTALLSLINT LGQIHKGLCR QLAVVLTAPG LQNYFLQCVA PAPAPQLTPF
950
951
SAWALRHEYH LQYLVLSLAQ KAATSQPEPA ASTALHHVMA LVLLSRLLPG
1000
1001
SEFLAHELLL SCVFRLGFLP ENASGGPEAA DFSDGLSLGN SGDPHCRRGA
1050
1051
LLVQACQDLP SIRSCYLAHC SPARASLLTS QALYRGELPR VSSLLLPVPK
1100
1101
EPLLPTDWPF QPLIHLYHRA SDTPSGLPAA DTVGITMRVL QWVLVLESWR
1150
1151
PEALWAVPPA ARLARLMCVY LVDSELFRET PIQRLVAALL ARLCQPQVLP
1200
1201
NLKLDCPLPG LTSFPDLYAS FLDHFEAVSF GDHLFGALVL LPLQRRFSVT
1250
1251
LRLALFGEHV GVLRALGLPL AQLPVPLECY TEPAEDSLAL LQLYFRALVT
1300
1301
GALHARWCPV LYTVAVAHVN SFVFCQDPKS SDEVKAARRS MLQKVWLLAD
1350
1351
KDLRQHLLHY KLPNSSLPEG FELYPQLPRL RQQYLQTLPT EVLQNGGFKT
1400
1401
                                                      
1400
 

Show the unformatted sequence.

Checksums:
CRC64:7E9A525448EBC6B3
MD5:c4272a9dffa7dfe81ae55459316c656e

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;