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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: Q4D1I2_TRYCC (Q4D1I2)

Summary

This is the summary of UniProt entry Q4D1I2_TRYCC (Q4D1I2).

Description: Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114}
Source organism: Trypanosoma cruzi (strain CL Brener) (NCBI taxonomy ID 353153)
Length: 592 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 44
low_complexity n/a 3 32
low_complexity n/a 28 54
low_complexity n/a 71 83
disorder n/a 76 90
disorder n/a 92 93
disorder n/a 96 99
Pfam WGR 132 211
disorder n/a 230 240
disorder n/a 242 244
Pfam PARP_reg 250 378
coiled_coil n/a 300 320
Pfam PARP 392 589
disorder n/a 399 400
disorder n/a 520 522

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q4D1I2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSPKKLSGAG KAPAAKKASA AKKASAVRKA PAGNKASAAK KAPAAKKASA
50
51
ARKALFPAVN NTVKIIPAKG AAPAAATAPP AATNVGGNSL TPATDVTGAK
100
101
VQQMLRKGRG VVDSFSGKVD TCHVYEKGSD VYQCTLNQTH VAANNNKYFI
150
151
IQLLEDDAES IYHVFTRWGR VGYGGQNKTV TFSSLGQALY LFEKTFCQKT
200
201
ANHWRSRAQF NAVKGRYELM DIDYGAAEDE AEKSGESSAA RGPAEKPVIS
250
251
ALPGEVQGLL KLIGCKETMK RLMAEYAINT EKLPLGKISQ GQITRANSVL
300
301
KSLEAEMKKA NPRLEELSDQ FYTLIPHAFG RSRPPLISSE SILRQKMEML
350
351
EALGKLEVAV SILNAEAPEE IHPLDKLYRR LNCEITPLSR DEPDFRRIVE
400
401
YANNTRGPTH KFHVEVKQVF TVRRKDEDDL YGSFKRLGNR QMLWHGSRIT
450
451
NFIGILSQGL RIAPPEAPCT GYMFGKGIYL ADVCTKSANY CYPSRDTKTG
500
501
LMLLCEAALG KQMELTDSKY MENPMPGTNA TKGVGSYFPD PAGAEVVDGV
550
551
LWPKGRVRES RISSSLLYPE HIIYNVGQCR MRWLVHVGFK YH        
592
 

Show the unformatted sequence.

Checksums:
CRC64:7114454E6EB442A5
MD5:51164f2647792f94e3066803ea939f8a

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;