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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: Q4E4P5_TRYCC (Q4E4P5)

Summary

This is the summary of UniProt entry Q4E4P5_TRYCC (Q4E4P5).

Description: DNA-directed RNA polymerase subunit beta {ECO:0000256|RuleBase:RU363031}
Source organism: Trypanosoma cruzi (strain CL Brener) (NCBI taxonomy ID 353153)
Length: 1591 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 45
low_complexity n/a 6 16
low_complexity n/a 22 34
disorder n/a 103 107
disorder n/a 112 113
disorder n/a 284 286
low_complexity n/a 311 324
Pfam RNA_pol_Rpb2_1 370 766
disorder n/a 673 674
disorder n/a 676 677
Pfam RNA_pol_Rpb2_3 835 900
Pfam RNA_pol_Rpa2_4 951 1021
Pfam RNA_pol_Rpb2_6 1084 1483
disorder n/a 1222 1223
disorder n/a 1328 1329
low_complexity n/a 1459 1470
disorder n/a 1463 1486
low_complexity n/a 1478 1490
Pfam RNA_pol_Rpb2_7 1485 1587

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q4E4P5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSKNPSLRSS RSHNSSVGEN YTSTRSSVSS RHRRQEQKRE VLLPPANMTP
50
51
FERLQLLRNA LTRMQYIGER HLHSAMLDTA GGEKVLCFFE KLRERLPKLE
100
101
YNPRKLGCPE GNGPKQLQYI REQTLILQDA ANVVLKSCEA QKGKCDAVYE
150
151
GLSYHYLQEV LRELEEIQHL LSHAPSEMPS RVNTDLLADL VSFQINEFDA
200
201
FAEQRVEAFV SEAKNEGTLF TAVVNELSQR APSSTGLVSI FVLDVAIGVR
250
251
PGRCARIVIE HAQHNLTKLE NRLHTAGSVL SAMTSEKDLP TETQRRELAI
300
301
LKDRVSGSLA ELIRLKKKWE EEELRTFERA ASGQHVLLSL VEMKRLKEAE
350
351
IIEEAQLIHD RAMHSCLLFS APQYYRRYSE TYAQPCHVQI GFKFLQGEQV
400
401
ESQPKSMTLY ALVPEFFSLM RQHNIPAQEH ERYAALVPSK HHVWVSFSEF
450
451
PEMVRGARCS LRGVDTRNDH FRAFEEQKEV GGYFIMRGGE RILRALLMQR
500
501
CNVPLNIFRE RFSSQGPFFS PKAVVIRCKR PSGLTIQNYF YYATTGEVVF
550
551
SFARKVVWHI PVLLLLFSLN TRHCSSLEMY KLLTIGFTNC SSSHVARVEA
600
601
LLQHHHQKPY GSLVHFLDYM GVLGQMYRKY HETSNTFHFL PQFHSTCQGQ
650
651
HDVWYGLFML RRHVLPHLNV NEPTRDLSPT ATQEECVNWL SPKLLQELNA
700
701
KLDAMIAIVR QLYAFFDGAN EHQGNDVPAY QEIFTVSQVL MGGFEVCLNK
750
751
YMKSFVYRLG SHIPSHLFQS ILQLGELPGN ESSGVINQLR QYTDYCERRS
800
801
INEPLDALHR LLITGNLTLD REEDFYCPQT SGWVVMAEHL NFYRFFEQLR
850
851
CLHRGKTIAE MRSSEVRKYP CEAFGFICMV HSPDGADCGV LNHMSVSTFV
900
901
SESVPTGSRN EEDLLSRITE EFHGLRNGGS LDSLVDRLVG TVPVWVEGKM
950
951
LGYLAPEEAE RVCKALLRKK ALKTGSSMEL SGIVRRHSVN AFSMVEVVYV
1000
1001
PPGNKDPQGL YIFYDNGRMM RPVQQIESTS HGDELPFPLV YIGTWEQTWL
1050
1051
DIASVPSDLL DGLTQLNRKY EFMEQNGSNI LSLTSATIPF FEHNCSPRNL
1100
1101
FQCGLSKQSA GTQLQTLAWR KEAKLFRMYC PQRYISRTLP MDYYGLDDVN
1150
1151
LGVNAVIAIL AYTGYDLDDA VILNSTASQF GMLTAGITVA KVITASGKGE
1200
1201
KDDVFVFQNL LSNGQPFTPE LDAHGLPRKR AVPGTTELLS FDSDHKYPTL
1250
1251
RDSSAVYCCA KRYERIDPLM NKKVYEYTRH HVTKWWQFDK GENAWVHSVV
1300
1301
PLKYDGPDPT SALVVFRIPR PTAIGDKFSS RHGQKGTLPL HIRAYDLPFS
1350
1351
TRDGITPDII INPHAFPSRM TVGMVLEMMG AKLGAIQGRF CDHSAWSVVD
1400
1401
ERPRSAEVIG DALQKAGYNR YGREKLIDGI SGEEMEADVF MGISGYQRLR
1450
1451
HMVNDKWQAR ARTDAHTHRA VTKTGQPVKG RKRHGGVRVG EMERDGLLSH
1500
1501
GSAEVVLDRL LHVSDKAKAF ICVECGSLLS IYERHATEYS TWKTCKFCGA
1550
1551
GSQEATDTIA FVEIPQVLRL WAAELTGIGI RVVLKTRDEA S         
1591
 

Show the unformatted sequence.

Checksums:
CRC64:5AD6874A57F48B1D
MD5:c09a9603f73c65171fa2cc71eea9d857

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;